欧来良



招生专业： 生物化学与分子生物学
电话： **

邮箱： ouyll@nankai.edu.cn
办公地点： 分子所102







个人资料
性别： 男
部门： 生物材料与组织工程系
联系电话： **
通讯地址：
职称： 教授
电子邮箱： ouyll@nankai.edu.cn
办公地址： 分子所102


教育经历


工作经历
2003.07-2005.12 南开大学生命科学学院 讲师2006.01-2008.09 南开大学生命科学学院 副教授2008.10-2010.10 德国罗斯托克大学 博士后研究员2010.11-2010.12 南开大学生命科学院 副教授2011.01-今 南开大学生命科学学院 教授


个人简介
欧来良, 男,教授，博导，国家十三五重点研发计划首席科学家，致力于生物活性材料中血液净化材料的学、研、产、用”的系统研究与开发。2008年-2010年赴德国罗斯托克大学做博士后研究员，主要从事生物医学工程研究。迄今已在国内外重要期刊发表论文50余篇,申请发明专利20余项，获得天津市产学研突出贡献奖1项，天津自然科学二等奖1项。主持十三五国家重点研发计划、国家自然科学基金、天津市重点基金、科技部科研项目10余项，参加了3期“973”研究计划。参与起草并制定了2项国家标准天津市工艺协会理事，国际杂志JCMM特约审稿人；滨海新区心血管转化医学联盟副理事长，天津市抗癌新药创制联盟理事，中关村血液净化诊疗创新联盟 理事，天津市滨海新区侨联、留联理事会理事,中国新材料学会常务理事。


研究方向
1、血液净化材料与工程
2、生物分离与检测技术
3、吸附分离材料与工程



科研成果
代表性论文
Chen J, Sun J, Han W, Chen J, Wang W, Cheng G, Lin J, Ma N, Chen H, Ou L*, Li W. Computer-aided design of short peptide ligands targeting tumor necrosis factor-alpha for adsorbent applications. Journal of Materials Chemistry B, 2018; 6, 4368-4379.
Chen J, Cheng G, Chai Y, Han W, Zong W, Chen J, Li C, Wang W,Ou L*, Yu Y.Preparation of nano-CaCO3/polystyrene nanocomposite beads for efficient bilirubin removal.Colloids Surf B Biointerfaces. 2018 Jan 1;161:480-487.
Cheng G, Chai Y, Chen J, Chen J, Zhang Q, Ji S, Ou L*, Yu Y.Polystyrene-divinylbenzene based nano-CaCO3?composites for the efficient removal of human tumor necrosis factor-α.Chem Commun (Camb). 2017 Jul 6;53(55):7744-7747
Zong W, Chen J, Han W, Cheng G, Chen J, Wang Y, Wang W, Ou L*, Yu Y, Shen J.Preparation of PVA/amino multi-walled carbon nanotubes nanocomposite microspheres for endotoxin adsorption.Artif Cells Nanomed Biotechnol. 2018 Feb;46(1):185-191.
Zong W, Chen J, Han W, Chen J, Wang Y, Wang W, Cheng G, Ou L*, Yu Y.Preparation of chitosan/amino multiwalled carbon nanotubes nanocomposite beads for bilirubin adsorption in hemoperfusion.J Biomed Mater Res B Appl Biomater. 2018 Jan;106(1):96-103.
Chen J, Han W, Su R, Chen J, Zong W, Wang Y, Wang W, Cheng G,Ou L*, Yu Y.Non-ionic macroporous polystyrene adsorbents for removal of serum toxins in liver failure by hemoperfusion.Artif Cells Nanomed Biotechnol. 2016 Feb 2:1-10.
Chen J, HanW,Chen J, Zong W, Wang W, Wang Y ,Cheng G, Ou L*, Yu Y. High performance of a unique meso-porous polystyrene based adsorbent for blood purification.Regenerative Biomaterials,2016,1-7,DOI:10-1093
Yao X, Liu Y, Gao J, Yang L, Mao D, Stefanitsch C, Li Y, Zhang J, Ou L, Kong D, Zhao Q, Li Z.Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction.Biomaterials. 2015 Aug;60:130-40. doi: 10.1016
Liu Y, Ye X, Mao L, Cheng Z, Yao X, Jia X, Mao D, Ou L, Li Z, Che Y, Liu N, Steinhoff G, Liu L, Kong D.Transplantation of parthenogenetic embryonic stem cells ameliorates cardiac dysfunction and remodelling after myocardial infarction.Cardiovasc Res. 2013 Feb 1;97(2):208-18.
Mao L, Wang H, Tan M, Ou L, Kong D, Yang Z.Conjugation of two complementary anti-cancer drugs confers molecular hydrogels as a co-delivery system.Chem Commun (Camb). 2012 Jan 11;48(3):395-7.
Zhang, JX, Ou L*.Kinetic, isotherm and thermodynamic studies of the adsorption of crystal violet by activated carbon from peanut shellsWater science and technology, 2013,67,737-744
Zhang, JX;Zhou, QX;Ou L*.Kinetic, Isotherm, and Thermodynamic Studies of the Adsorption of Methyl Orange from Aqueous Solution by Chitosan/Alumina Composite.J.Chem. Eng. Data. 2012,57,412-419
Ou L, Li W, Zhang Y, Wang W, Liu J, Sorg H, Furlani D, G?bel R, Mark P, Klopsch C, Wang L, Lützow K, Lendlein A, Wagner K, Klee D, Liebold A, Li RK, Kong D, Steinhoff G, Ma N. Intracardiac injection of matrigel induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model.J Cell Mol Med. 2011 Jun;15(6):1310-8.
Ou L*, Li W, Liu Y, Zhang Y, Jie S, Kong D, Steinhoff G, Ma N. Animal models of cardiac disease and stem cell therapy.Open Cardiovasc Med J. 2010 Nov 26;4:231-9.
Wang W, Li W,Ou L, Flick E, Mark P, Nesselmann C, Lux CA, Gatzen HH, Kaminski A, Liebold A, Lützow K, Lendlein A, Li RK, Steinhoff G, Ma N. Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients.J Cell Mol Med. 2011 Sep;15(9):1989-98.
Liu X, Duan B, Cheng Z, Jia X, Mao L, Fu H, Che Y, Ou L*, Liu L, Kong D. SDF-1/CXCR4 axis modulates bone marrow mesenchymal stem cell apoptosis, migration and cytokine secretion.Protein Cell. 2011 Oct;2(10):845-54.
Wang K, Guan Y, Liu Y, Zhu M, Li T, An D, Ou L*，et,al. Fibrin glue with autogenic bone marrow mesenchymal stem cells for urethral injury repair in rabbit model.Tissue Eng Part A. 2012 Dec;18(23-24):2507-17
Zhang JX, Ou L*.Kinetic, isotherm and thermodynamic studies of the adsorption of crystal violet by activated carbon from peanut shells. Water Science & Technology, doi: 10.2166/wst.2012.605
Shen J, Fu ,Ou L*, Zhang M, Guan Y, Wang K, Che Y, Kong D, Steinhof G, Li W, Yu Y, Ma N. Construction of ureteral grafts by seeding urothelial cells and bone marrow mesenchymal stem cells into polycaprolactone-lecithin electrospun fibers.Int J Artif Organs. 2010 Mar;33(3):161-70.
Cheng Z＃, Ou L＃, Zhou X, Li F, Jia X, Zhang Y, Liu X, Li Y, Ward CA, Melo LG, Kong D. Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Molecular Therapy, 2008 Mar;16(3):571-9.
Cheng Z, Liu X,Ou L*, Zhou X, Liu Y, Jia X, Zhang J, Li Y, Kong D. Mobilization of mesenchymal stem cells by granulocyte colony-stimulating factor in rats with acute myocardial infarction.Cardiovasc Drugs Ther. 2008 Oct;22(5):363-71.
Cheng Z, Ou L, Liu Y, Liu X, Li F, Sun B, Che Y, Kong D, Yu Y, Steinhoff G. Granulocyte colony-stimulating factor exacerbates cardiac fibrosis after myocardial infarction in a rat model of permanent occlusion. Cardiovascular Research. 2008 Dec 1;80(3):425-34.
Ou L, Li W, Liu Y, Zhang , Jie S, Kong D, Steinhoff G, Ma N. Animal models of cardiac disease and stem cells therapy. Open Cardiovasc Med J. Open Cardiovasc Med J. 2010 Nov 26;4:231-9.




社会兼职
天津市政治协商会议委员会委员
全国材料新技术发展研究会常务理事
天津市抗癌新药创制产业技术战略联盟理事
天津市滨海新区心血管医学转化产业联盟，常务理事
中关村血液净化诊疗技术创新联盟，常务理事





教学经历



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