姓名：陈则友
职称：副教授
研究领域：环境微生物学、微生物生态学、环境化学
研究兴趣：1.环境抗生素耐药组的来源分布、传播扩散和健康风险；
2. 抗生素类污染物的环境行为过程和生态健康危害。
邮箱: zeyou@nankai.edu.cn

教育背景2013.10—2016.6，美国密西根州立大学，联合培养博士
2010.9—2016.6，南京农业大学，硕博连读
科研教学经历2019.02至今，南开大学，副教授
2017.12-2018.12，南京大学，助理研究员
2016.6-2017.11，美国密西根州立大学，博士后
科研项目1. 国家自然科学基金面上项目（**），耐药性人类条件致病菌及其携带的耐药基因在土壤-植物系统中的传输规律、扩散机制及健康风险研究，61万，2020.1-2023.12（主持）。
2. 国家自然科学基金青年项目（**），利用全细胞微生物传感器研究四环素的典型环境行为对细菌抗性基因表达的影响及机理，25万，2019.1-2021.12（主持）。
3. 江苏省自然科学基金青年项目（BK**），抗生素抗性基因在动物粪便-好氧堆肥-农田施用全过程中的迁移和归趋研究，20万，2018.7-2021.6（主持）。
4. 南京大学中央高校基本科研业务费专项资金资助（）。利用全细胞微生物传感器研究四环素的典型环境行为对细菌抗性基因表达的影响及机理，10万，2018.1-2018.12（主持）。
学术论著1.Xiaolong Wang(#), Zeyou Chen(#), Quanhua Mu, Xinyan Wu, Jingjing Zhang, Daqing Mao, Yi Luo, Pedro J. J. Alvarez, Ionic liquid Enriches the Antibiotic Resistome, Especially Efflux Pump Genes, Before Significantly Affecting Microbial Community Structure.Environmental Science &Technology,2020, 54, 7, 4305-4315
2.Yujing Duan(#), Zeyou Chen(#), Lu Tan, Xiaolong Wang, Yingang Xue, Shaopeng Wang, Qing Wang, Ranjit Das, Huai Lin, Jie Hou, Linyun Li, Daqing Mao, Yi Luo,Gut resistomes, microbiota and antibiotic residues in Chinese patients undergoing antibiotic administration and healthy individuals.Science of The Total Environment, 2020:705:135674.
3.Jie Hou (#), Zeyou Chen(#), Ju Gao, Yonglei Xie, Linyun Li, Songyan Qin, Qing Wang, Daqing Mao, Yi Luo, Simultaneous removal of antibiotics and antibiotic resistance genes from pharmaceutical wastewater using the combinations of up-flow anaerobic sludge bed, anoxic-oxic tank, and advanced oxidation technologies. Water Research, 2019:159:511-520.
4.Zeyou Chen, Wei Zhang, Luxi Yang, Robert D. Stedtfeld, Anping Peng, Cheng Gu, Stephen A. Boyd, Yanzheng Gao, and Hui Li. Antibiotic Resistance Genes and Bacterial Communities in Cornfield and Pasture Soils Receiving Swine and Dairy Manures. Environmental Pollution, 2019:248:947-957.
5.Zeyou Chen, Wei Zhang, Wang Gang, Yingjie Zhang, Yanzheng Gao, Stephen A. Boyd, Brian J. Teppen, James M. Tiedje, Dongqiang Zhu, and Hui Li. Bioavailability of Soil-sorbed Tetracycline to Escherichia coli under Unsaturated Conditions. Environmental Science &Technology. 2017:51:6165-6173.
6.Zeyou Chen, Yingjie Zhang, Yanzheng Gao, Stephen A. Boyd, Dongqiang Zhu, and Hui Li. Influence of Dissolved Organic Matter on Tetracycline Bioavailability to an Antibiotic-Resistant Bacterium. Environmental Science & Technology. 2015:49: 10903?10910.
7.Zeyou Chen, Hui Li, Yanzheng Gao, and Anping Peng. Removal of Phenanthrene and Acenaphthene from Aqueous Solution by Enzyme-catalyzed Phenol Coupling Reactions. Chemical Engineering Journal. 2015:265:27–33.
8.Zeyou Chen, Hui Li, Anping Peng, and Yanzheng Gao. Oxidation of Polycyclic Aromatic Hydrocarbons by Horseradish Peroxidase in Water Containing Organic Cosolvent. Environmental Science and Pollution Research. 2014:21:10696-10705.
9.Huai Lin(#), Qing Wang(#), Meng Yuan, Lei Liu, Zeyou Chen, Yanhui Zhao, Ranjit Das, Yujing Duan, Ximing Xu, Yingang Xue, Yi Luo, Daqing Mao. The prolonged disruption of a single-course amoxicillin on mice gut microbiota and resistome, and recovery by inulin,Bifidobacterium longumand fecal microbiota transplantation. Environmental Pollution. 2020. In press.
10.Peng Anping, Juan Gao, Zeyou Chen, Yi Wang, Hui Li, Lena Q. Ma, and Cheng Gu. Interactions of Gaseous 2-Chlorophenol with Fe³⁺-Saturated Montmorillonite and their Toxicity to Human Lung Cells. Environmental science & technology. 2018, 52 (9)：5208–5217.
11.Anping Peng, Mengyu Huang, Zeyou Chen, and Cheng Gu. Oxidative Coupling of Acetaminophen Mediated by Fe³⁺-saturated Montmorillonite. Science of the Total Environment, 2017: 595: 673-680.
12.Anping Peng, Juan Liu, Wanting Ling, Zeyou Chen, and Yanzheng Gao. Diversity and Distribution of 16S rRNA and Phenol Monooxygenase Genes in the Rhizosphere and Endophytic Bacteria Isolated from PAH-contaminated Sites. Scientific Reports. 2015: 5: 12173.
13.Yi Wang, Anping Peng, Zeyou Chen, Xin Jin, Cheng Gu.Transformation of gaseous 2-bromophenol on clay mineral dust and the potential health effect. Environmental Pollution. 2019. 250:686-694.
14.Anping Peng, Juan Liu, Yanzheng Gao, Zeyou Chen. Distribution of Endophytic Bacteria in Alopecurus aequalis Sobol and Oxalis corniculata L. from Soils Contaminated by Polycyclic Aromatic Hydrocarbons, PLoS ONE, 2013: 8(12): e83054.