姓名：赵洪芝
职务职称：副教授
研究领域：环境污染物的人体暴露与代谢组学研究
邮箱：hongzhizhao@nankai.edu.cn














教育背景
2009.9-2012.12 南开大学药学院化学生物学专业攻读博士学位
2003.9-2006.3 天津大学化工学院生物化工专业攻读硕士学位
1999.9-2003.7 天津大学化工学院制药工程专业攻读学士学位
科研教学经历
2019.9-至今南开大学环境科学与工程学院，副教授
2014.7-2019.8 香港浸会大学（HKBU）环境与生物分析国家重点实验室，博士后
2013.3-2014.3 比利时鲁汶大学（K. U. Leuven）生物系，博士后

科研项目
1. 国家自然科学基金-青年基金（项目主持人）：基于质谱技术的双酚A与DNA加合物检测方法的研究及其应用（NSFC **），21万元，2016年1月-2018年12月，主持；
2. 国家自然科学基金-重点项目：太原和广州市大气细颗粒物诱导呼吸系统疾病的质谱代谢组学研究（NSFC **），275万元，2016年1月-2019年12月，参与。

学术论著
以第一作者发表文章19篇，其中SCI收录文章13篇（含共同一作），通讯作者SCI收录文章1篇，以其他共同作者发表SCI收录文章40篇，代表作如下：

（1）一作或通讯作者文章：
1.Hongzhi Zhao#, Han Li#, Yuanyuan Zheng, Lin Zhu, Jing Fang, Li Xiang, Shunqing Xu, Yanqiu Zhou, Hemi Luan, Wei Xia*, Zongwei Cai*, Association of altered serum acylcarnitine levels in early pregnancy and risk of gestational diabetes mellitus. SCIENCE CHINA Chemistry, 2019 (in press) (DOI: 10.1007/s11426-019-9580-2)
2.Yuanyuan Zheng#, Hongzhi Zhao#, Lin Zhu, Zongwei Cai*, Comprehensive identification of steroid hormones in human urine based on liquid chromatography-high resolution mass spectrometry. Analytica Chimica Acta, 2019 (in press) (DOI: 10.1016/j.aca.2019.09.058) (co-first auther)
3.Hongzhi Zhao#, Han Li#, Arthur Chi Kong Chung, Li Xiang, Xiaona Li, Yuanyuan Zheng, Hemi Luan, Lin Zhu, Wenyu Liu, Yang Peng, Yaxing Zhao, Shunqing Xu, Yuanyuan Li*, Zongwei Cai*, Large-Scale Longitudinal Metabolomics Study Reveals Different Trimester-specific Alterations of Metabolites in Relation to Gestational Diabetes Mellitus. Journal of Proteome Research. 2019, 18 (1), 292-300
4.Jie Hu#, Hongzhi Zhao#, Joseph M. Braun, Tongzhang Zheng, Bin Zhang, Wei Xia, Wenxin Zhang, Jiufeng Li, Yanqiu Zhou, Han Li, Jun Li, Aifen Zhou, Yiming Zhang, Stephen L. Buka, Simin Liu, Yang Peng, Chuansha Wu, Minmin Jiang, Wenqian Huo, Yingshuang Zhu, Kunchong Shi, Yuanyuan Li, Zongwei Cai*, Shunqing Xu*, Associations of Trimester-Specific Exposure to Bisphenols with Size at Birth: A Chinese Prenatal Cohort Study, Environmental Health Perspectives. 2019, 127(10): 107001 (DOI: 10.1289/EHP4664) (IF 8.049) (co-first author)
5.Yangqian Jiang#, Hongzhi Zhao#, Wei Xia, Yuanyuan Li, Hongxiu Liu, Ke Hao, Jia Chen, Xiaojie Sun, Wenyu Liu, Jiufeng Li, Yang Peng, Chen Hu, Chunhui Li, Bin Zhang, Shi Lu, Zongwei Cai*, Shunqing Xu*, Prenatal Exposure to Benzophenones, Parabens and Triclosan and Neurocognitive Development at 2 Years. Environment International, 2019, 126: 413-421 (co-first author)
6.Yuanyuan Zheng, Xiaona Li, Xiangfeng Chen, Zongwei Cai*, Hongzhi Zhao*, Simultaneous determination of amino acids, purines and derivatives in serum by UHPLC/MS/MS. Rapid Communications in Mass Spectrometry, 2019, 33: 81-88
7.Hongzhi Zhao, Jiufeng Li, Yanqiu Zhou, Lin Zhu, Yuanyuan Zheng, Wei Xia, Yuanyuan Li, Li Xiang, Wei Chen, Shunqing Xu*, Zongwei Cai*, Investigation on Metabolism of Di(2-Ethylhexyl) Phthalate in Different Trimesters of Pregnant Women. Environmental Science & Technology, 2018, 52(21): 12851-12858
8.Hongzhi Zhao, Juntong Wei, Li Xiang, Zongwei Cai*, Mass spectrometry investigation of DNA adduct formation from bisphenol A quinone metabolite and MCF-7 cell DNA. Talanta, 2018,182(5): 583-589
9.Hongzhi Zhao, Jiufeng Li, Xinli Ma, Wenqian Huo, Shunqing Xu*, Zongwei Cai*, Simultaneous determination of bisphenols, benzophenones and parabens in human urine by using UHPLC-TQMS. Chinese Chemical Letters, 2018, 29:102-106
10.Hongzhi Zhao#, Wenqian Huo#, Jiufeng Li, Xinli Ma, Wei Xia, Zhengji Pang, Mingyi Xie, Shunqing Xu*, Zongwei Cai*, Exposure to Benzophenones, Parabens and Triclosan among Pregnant Women in different trimesters. Science of the Total Environment, 2017, 607-608:578-585

（2）其他共同作者文章：
1. Jing Fang, Hongzhi Zhao, Yanhao Zhang, Minghung Wong, Yu He, Qianqian Sun, Shunqing Xu*, Zongwei Cai*, Evaluation of gas chromatography-atmospheric pressure chemical ionization tandem mass spectrometry as an alternative to gas chromatography tandem mass spectrometry for the determination of polychlorinated biphenyls and polybrominated diphenyl ethers. Chemosphere, 2019, 225: 288-294
2. Jing Fang, Hongzhi Zhao, Yanhao Zhang, Yu He, Qianqian Sun, Shunqing Xu*, Zongwei Cai*, Performance of atmospheric pressure gas chromatography-tandem mass spectrometry for the analysis of organochlorine pesticides in human serum. Analytical and Bioanalytical Chemistry, 2019, 411:4185-4191
3. Jiufeng Li, Hongzhi Zhao, Yanqiu Zhou, Shunqing Xu*, Zongwei Cai*, Nine phthalate metabolites in human urine for the comparison of health risk between population groups with different water consumptions. Science of The Total Environment, 2019, 649: 1532-1540
4. Qian Wu, Hongzhi Zhao, Xiangfeng Chen, Zongwei Cai*, Interaction of Bisphenol A 3, 4-quinone Metabolite with Human Hemoglobin, Human Serum Albumin and Cytochrome c in vitro. Chemosphere, 2019, 220: 930-936
5. Hongna zhang, Xiaojian Shao, Hongzhi Zhao, Xiaona Li, Juntong Wei, Chunxue Yang, Zongwei Cai*, Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes. Environmental Science & Technology. 2019, 53, 5406-5415
6. Jiufeng Li#, Xi Qian#, Hongzhi Zhao, Yanqiu Zhou, Shunqing Xu, Yuanyuan Li, Li Xiang, Jingchun Shi, Wei Xia*, Zongwei Cai*, Determinants of exposure levels, metabolism, and health risks of phthalates among pregnant women in Wuhan, China. Ecotoxicology and Environmental Safety, 2019: 184:109657
7. Jiufeng Li#, Chuansha Wu#, Hongzhi Zhao, Yanqiu Zhou, Guodong Cao, Zhiyi Yang, Yanjun Hong, Shunqing Xu, Wei Xia*, Zongwei Cai*, Exposure assessment of bisphenols in Chinese women during pregnancy: a longitudinal study. Environmental Science & Technology, 2019, 53, 13, 7812-7820
8. Jing Fang#, Hongxiu Liu#, Hongzhi Zhao, Yanqiu Zhou, Shunqing Xu*, Zongwei Cai*, Association of in utero hexachlorocyclohexane exposure with gestational age. Ecotoxicology and Environmental Safety, 174, 263-269
9. Jiufeng Li#, Wenyu Liu#, Wei Xia, Hongzhi Zhao, Yanqiu Zhou, Yuanyuan Li, Chuansha Wu, Hongxiu Liu, Bin Zhang, Yingshuang Zhu, Jie Hu, Xianliang Wang, Dan Ye, Shunqing Xu*, Zongwei Cai*, Variations, determinants, and co-exposure patterns of personal care product chemicals among Chinese pregnant women: a longitudinal study. Environmental Science & Technology, 2019, 53, 11, 6546-6555
10. Jiufeng Li#, Wei Xia#, Chuansha Wu, Hongzhi Zhao, Yanqiu Zhou, Juntong Wei, Fenfen Ji, Hemi Luan, Shunqing Xu, Zongwei Cai*, Variations of phthalate exposure and metabolism over three trimesters. Environmental Pollution, 2019, 251, 137-145