梁耀东,男,1967年10月出生于江苏省镇江市,1997年6月陕西师范大学硕士毕业,2006年西北大学博士毕业,所学专业分析化学,2005年晋升为副教授,2007年遴选为硕士生导师。
主讲课程:物理化学、结构化学、荧光及色谱分析、物质结构与分析方法
地址:陕西西安雁塔路中段58号;
电话:**
E-mail: liangyd@xust.edu.cn
学科方向名称:分子反应动力学
方向介绍:
分子间各种弱相互作用的加和与协同、分子间相互作用的方向性和选择性决定了分子识别、分子组装、组装体的特定结构和功能.生物分子通过共价键连接结构部件形成直链聚合物, 而大量的弱相互作用是将其独特的三维结构维持在一个动态的水平不可缺少的力量。生命科学的进展也表明弱相互作用在构筑生命体系(如细胞膜、DNA双螺旋)及酶识别、药物/受体识别等方面起到了重要作用。生物大分子都是在溶液尤其是水溶液中才具有特定的生理活性, 水分子的溶液结构很复杂, 使得水溶液的研究异常困难, 有关生物大分子与药物小分子在水溶液的相互作用已成为目前最具挑战性和最有活力的前沿之一。本方向以染料分子为探针,利用染料分子光、电信号的变化,研究药物小分子与染料之间的作用机理,为进一步解释药物与生物大分子之间相互作用提供直接依据。
曾经参与的科研项目:
参加了西北大学
主要发表文章:
1. Liang Yao-Dong, Song Jun-Feng, Yang Xiao-Feng, Flow-injection chemiluminescence determination of fluoroquinolones by enhancement of weak chemiluminescence from peroxynitrous acid, Anal. Chim. Acta, 2004, 510, 21-28.
2. Liang Yao-Dong, Song Jun-Feng, Yang Xiao-Feng, Guo Wei, Flow-injection chemiluminescence determination of chloroquine using peroxynitrous acid as oxidant,Talanta, 2004, 62, 757-763
3. Liang Yao-Dong, Song Jun-Feng, Flow-injection chemiluminescence determination of tryptophan through its peroxidation and epoxidation by peroxynitrous acid, J. Pharm. Biomed. Anal., 2005, 38, 100-106.
4. Liang Yao-Dong, Song Jun-Feng, Tian Tian, Determination of pipemidic acid based on flow-injection chemiluminescence due to energy transfer from peroxynitrous acid synthesized on-line, Anal. Bioanal. Chem., 2004, 380, 918-93.
5.Liang Yao-Dong, Gao Wei, Song Jun-Feng, Electrochemiluminescence determination of pipemidic acid using sulfite as energy transfer mediator, Bioorganic Med. Chem. Lett., 2006,16, 5328–5333
6. Liang Yao-Dong, Song Jun-Feng, Xu Min, Electrochemiluminescence from successive electro- and chemo- oxidation of rifampicin and its application to the determination of rifampicin in pharmaceutical preparations and human urine, Spectrochim. Acta, 2007, 67, 430–436.
7. Liang Yao-Dong, Song Jun-Feng. Electrochemiluminescence from direct electro-oxidations of organic analytt rutin and its analytical application.Journal of Electroanalytical chemistry, 2008, 624, 27–32.
8. Yao-Dong Liang, Chun-Xia Yu, Jun-Feng Song, Electrochemiluminescence of palmatine being oxidized by electrogenerated hydroxyl radical and its analytical application, Luminescence 2011;26: 178–184.
9. Yao-Dong Liang, Chun-Xia Yu, Jun-Feng Song, Cathodic electrochemiluminescence of the peroxydisulphate–ciprofloxacin system and its analytical applications, Luminescence 2011;26: 662–669.
10. Yao-Dong Liang,Chun-Xia Yu. Determination of berberine in pharmaceutical preparations using acidic hydrogen peroxide–nitrite chemiluminescence system. Drug Testing and Analysis, 2013, 5, 150–155
11. Ting Jiang, Yao-dong Liang, Yong-jun He, Qing Wang, Activated carbon/NiFe2O4 magnetic composite: A magnetic adsorbent for the adsorption of methyl orange, Journal of Environmental Chemical Engineering 2015, 3 ,1740–1751.
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