西安交通大学化学学院导师教师师资介绍简介-优良王

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Welcome - 优良王Basic Information/基本信息

Youliang Wang is a professor of School of Chemistry at Xi’an Jiaotong University. He obtained his BSc degree at University of Science and Technology of China in 2011, and Ph.D. degree at University of California-Santa Barbara under the direction of Prof. Liming Zhang in 2016.Subsequently, Youliang conducted his postdoctoral training at Stanford University with Prof. Barry M. Trost from October 2016 to January 2020. Youliang began his independent career at Xi’an Jiaotong University in January 2020, where his lab focuses on developing novel synthetic methods and applying them to the synthesis of bioactive molecules such as drugs and natural products.
王优良，博士，山东人，西安交通大学“青年拔尖人才”，化学学院教授，博士生导师。王优良教授课题组的主要研究方向为有机合成新方法的开发及其在药物、天然产物合成中的应用。目前已在Science, Nature Chemistry, J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Catal.等国际知名期刊发表论文18篇。

Contact Information/联系方式
通信地址：陕西省西安市长安区沣西新城中国西部科技创新港19号楼4143室。
邮编：710000。
电子邮箱/Email： youliangwang@xjtu.edu.cn

实验室内部氛围
尊重、平等、自由、友善

站点计数器

Education/教育经历
2007/09-2011/07, B. S. in chemistry, University of Science and Technology of China (USTC).
2011/07-2016/09, Ph. D. in chemistry, University of California-Santa Barbara. Supervisor: Prof. Liming Zhang.
2007/09-2011/07，中国科学技术大学，化学，学士，导师：王官武教授。
2011/07-2016/09，美国加利福尼亚大学-圣塔芭芭拉分校，有机化学，博士，导师：Liming Zhang教授。

Professional Employment/工作经历
2016/10-2020/1, Post-doctoral researcher, Stanford University. Supervisor: Prof. Barry M. Trost.
2020/1-present, Professor, Department of Chemistry, Xi'an Jiaotong University.
2016/10-2020/01，美国斯坦福大学，有机化学，博士后，合作导师：Barry M. Trost教授。
2020/01-至今，西安交通大学，教授。

Research Areas/研究领域
1. Development of novel synthetic methods
2. Total synthesis of drugs and natural products
1.有机合成新方法的开发
2.药物、天然产物全合成

Recruitment/招贤纳士
实验室长期招聘硕士、博士研究生，欢迎化学、药学等专业背景的同学推免或者报考！
实验室长期招聘研究助理，也欢迎广大本科生同学来实验室学习！
此外，诚挚欢迎海内外已毕业或者即将毕业的博士以博士后或西安交通大学“青年优秀人才”的身份加入团队！
联系方式（Email）：youliangwang@xjtu.edu.cn

Publications/发表论文 - 优良王 18.Pd(0)-Catalyzed Diastereo- and Enantioselective Intermolecular Cycloaddition for Rapid Assembly of 2-Acyl-methylenecyclopentanes.
Barry M. Trost,* Zhijun Zuo, Youliang Wang.
Org. Lett.,2021,23, 979-983.

17.Non‐Diazo C?H Insertion Approach to Cyclobutanones through Oxidative Gold Catalysis.
Zhitong Zheng,?Youliang Wang,?Xu Ma, Yuxue Li, Liming Zhang.*
Angew. Chem. Int. Ed.,2020,59, 17398-17402.(?共同一作)

16. Pd(0)-Catalyzed Chemo-, Diastereo-, and Enantioselective α-Quaternary Alkylation of Branched Aldehydes.
Barry M. Trost,*Zhijun Zuo,?Youliang Wang,?and Johnathan E. Schultz.
ACS Catal.,2020,10, 9496-9503.(?共同一作)

15. Total Synthesis of Bryostatin 3.
Barry M. Trost,* Youliang Wang, Andreas K. Buckl, Zhongxing Huang, Minh H. Nguyen, Olesya Kuzmina.
Science 2020, 368, 1007-1011.

14. Use of α-Trifluoromethyl Carbanions for Palladium-Catalysed Asymmetric Cycloadditions.
Barry M. Trost,* Youliang Wang,? Chao-I (Joey) Hung.?
Nature Chemistry 2020, 12, 294-301. (? 共同一作)

13. Palladium-Catalyzed Regio-, Enantio-, and Diastereoselective Asymmetric [3 + 2] Cycloaddition Reactions: Synthesis of Chiral Cyclopentyl Phosphonates.
Barry M. Trost,* Anand H. Shinde,? Youliang Wang,? Zhijun Zuo, Chang Min.
ACS Catal., 2020, 10, 1969-1975. (? 共同一作)

12. A Deprotonation Approach to the Unprecedented Amino-Trimethylenemethane Chemistry: Regio-, Diastereo-, and Enantioselective Synthesis of Complex Amino Cycles.
Barry M. Trost,* Youliang Wang.
Angew. Chem. Int. Ed., 2018, 57, 11025-11029.

11. A C-H Insertion Approach to Functionalized Cyclopentenones.
Youliang Wang, Maxence Zarca, Liu-Zhu Gong, Liming Zhang.*
J. Am. Chem. Soc., 2016, 138, 7516-7519.

10. Intramolecular Insertions into Unactivated C(sp3)-H Bonds by Oxidatively Generated β-Diketone-α-Gold Carbenes: Synthesis of Cyclopentanones.
Youliang Wang, Zhitong Zheng, Liming Zhang.*
J. Am. Chem. Soc., 2015, 137, 5316-5319.

9. Ruthenium-Catalyzed Oxidative Transformations of Terminal Alkynes to Ketenes by Using Tethered Sulfoxides: Access to β-Lactams and Cyclobutanones.
Youliang Wang, Zhitong Zheng, Liming Zhang.*
Angew. Chem. Int. Ed., 2014, 53, 9572-9576.

8. Gold-Catalyzed Cyclizations of cis-Enediynes: Insights into the Nature of Gold–Aryne Interactions.
Youliang Wang, Akop Yepremyan, Subir Ghorai, Robert Todd, Donald H. Aue,* Liming Zhang.*
Angew. Chem. Int. Ed., 2013, 52, 7795-7799.

7. Direct Conversion of Internal Alkynes into α-Iodoenones: One-Step Collaborative Iodination and Oxidation.
Youliang Wang, Alexandre Genoux, Subir Ghorai, Hongyi Chen, Robert Todd, Liming Zhang.*
Adv. Synth. Catal., 2016, 358, 1417-1420.

6. Recent Developments in the Chemistry of Heteroaromatic N-Oxides.
Youliang Wang, Liming Zhang.
Synthesis 2015, 47, 289.

5. Au Catalyzed Oxidative Cyclisation.
Zhitong Zheng, Zhixun Wang, Youliang Wang, Liming Zhang.
Chem. Soc. Rev. DOI: 10.1039/C5CS00887E.

4. Ruthenium-catalyzed rearrangement of propargyl sulfoxides: formation of α,β-unsaturated thioesters.
Renhua Zheng, Youliang Wang, Liming Zhang.
Tetrahedron Lett., 2015, 56, 3144-3146.

3. [3,3]-Sigmatropic Rearrangement versus Carbene Formation in Gold-Catalyzed Transformations of Alkynyl Aryl Sulfoxides: Mechanistic Studies and Expanded Reaction Scope.
Biao Lu, Yuxue Li, Youliang Wang, Donald H. Aue, Yingdong Luo, Liming Zhang.
J. Am. Chem. Soc., 2013, 135, 8512-8524.

2. Palladium-catalyzed heteroannulation of [60] fullerene with N-benzyl sulfonamides and subsequent functionalisation.
Yi-Tan Su, Youliang Wang, Guan-Wu Wang.
Chem. Commun., 2012, 48, 8132-8134.

1. Palladium-catalyzed heteroannulation of [60]fullerene with N-(2-arylethyl) sulfonamides via C–H bond activation.
Yi-Tan Su, Youliang Wang, Guan-Wu Wang.
Org. Chem. Front., 2014, 1, 689-693.