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西北农林科技大学动物科技学院导师教师师资介绍简介-王小龙

本站小编 Free考研考试/2021-07-07


  1.基本信息
  王小龙,男,1983年生,教授,博士生导师。2005年和2008年分别在西北农林科技大学动物科技学院获本科和硕士学位。2013年获德国慕尼黑工业大学动物育种研究所自然科学博士学位。2016年晋升为副教授,2019年破格晋升为教授。
  目前兼任国际动物遗传学会羊应用遗传学专业委员会执委(Standing Committee)、基因编辑动物专业委员会执委,Reproduction, Fertility & Development副主编(Associate Editor),Journal of Animal Science编委(Editorial board),数个国内外期刊审稿人。
  入选“陕西省科技新星”(2017)和“西北农林科技大学仲英青年****”(2016)。
  联系方式:xiaolongwang@nwafu.edu.cn;xiaolong.wang@vip.163.com
  2.研究方向
  主要从事羊的遗传育种研究工作,研究方向聚焦于:羊的基因编辑与种质创新;羊经济性状功能基因的挖掘;绒山羊次级毛囊生长和发育调控机制。
  3.主讲课程及人才培养
  主要承担《羊生产学》(本科生)及《动物遗传繁育进展》(研究生)等课程。
  现指导硕士研究生7人,其中2人获研究生国家奖学金,1人获校长奖学金。
  4.主持科研项目
  (1)国家自然科学基金(面上项目),基于CRISPR文库筛查技术的绒山羊毛囊干细胞增殖必需基因鉴定及功能研究,2018/01-2021/12,60万元,在研,主持
  (2)国家重点研发计划子课题,北方农区绵羊高效安全养殖技术应用与示范,2018/01-2020/12,41万元,在研,主持
  (3)陕西省青年科技新星,2017年,10万元,在研,主持
  (4)仲英青年****,2016年,羊的遗传育种,36万,在研,主持
  (5)西藏地区高原家养种质资源优异基因挖掘,48万,在研,主持
  (6)国家自然科学基金(青年基金)。(已结题)
  (7)中国博士后科学基金(特等资助、一等资助)。(已结题)
  (8)陕西省留学归国人员配套资助项目。(已结题)
  (9)教育部留学回国人员科研启动基金。(已结题)
  (10)陕西省博士后项目资助。(已结题)
  (11)中央高校基本科研业务费。(已结题)
  (12)陕西省自然科学基金(面上项目)。(已结题,优秀)
  5.代表性学术论文
  G. Li, S. Zhou, C. Li, B. Cai, H. Yu, B. Ma, Y. Huang, Y. Chen, X. Wang#, Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair, FEBS Journal . accepted.
  S. Zhou, B. Cai, C. He, Y. Wang, Q. Ding, J. Liu, Y. Liu, Y. Chen, X. Wang#, Programmable Base Editing of the Sheep Genome Revealed No Genome-Wide Off-Target Mutations, Frontiers in Genetics . 10 (2019).
  C. Li, S. Zhou ,Y. Li, G. Li, Y. Ding, L. Li, Y. Jiang, Y. Chen, X. Wang#, Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats, Frontiers in Genetics .9 (2018).
  C. Li, Y. Li, G. Zhou, Y. Gao, S. Ma, Y. Chen, J. Song, X. Wang#, Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling, BMC Genomics . 19 (2018) 638.
  Y. Li, G. Zhou, R. Zhang, J. Guo, C. Li, G. Martin, Y. Chen, X. Wang#, Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats, Journal of Proteomics . 172 (2018) 82–88.
  Y. Lei, K. Zhang, M. Guo, G. Li, C. Li, B. Li, Y. Yang, Y. Chen, X. Wang#, Exploring the Spatial-Temporal Microbiota of Compound Stomachs in a Pre-weaned Goat Model, Front ier s in Microbiology . 9 (2018).
  X. Wang, J. Liu, Y. Niu, Y. Li, S. Zhou, C. Li, B. Ma, Q. Kou, B. Petersen, T. Sonstegard, X. Huang, Y. Jiang, Y. Chen, Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep, BMC Genomics . 19 (2018) 397.
  X. Wang, Y. Niu, J. Zhou, H. Zhu, B. Ma, H. Yu, H. Yan, J. Hua, X. Huang, L. Qu, Y. Chen, CRISPR/Cas9-mediated MSTN disruption and heritable mutagenesis in goats causes increased body mass, Animal Genetics . 49 (2018) 43–51. (引用12次)
  X. Wang, H. Yu, A. Lei, J. Zhou, W. Zeng, H. Zhu, Z. Dong, Y. Niu, B. Shi, B. Cai, J. Liu, S. Huang, H. Yan, X. Zhao, G. Zhou, X. He, X. Chen, Y. Yang, Y. Jiang, L. Shi, X. Tian, Y. Wang, B. Ma, X. Huang, L. Qu, Y. Chen, Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system, Scientific Reports . 5 (2015) 13878. (引用73次)
  X. Wang, C. Wurmser, H. Pausch, S. Jung, F. Reinhardt, J. Tetens, G. Thaller, R. Fries, Identification and dissection of four major QTL affecting milk fat content in the German Holstein-Friesian population, PLoS ONE . 7 (2012) e40711. (引用68次)
  (# 通讯作者)
  6.主要国际会议(交流)
  “Genome-wide off-target mutations in edited animals”, Genome Writers Guide Conference, Ames, Iowa, May 2019 (大会报告)
  “Trio-based Deep Sequencing Reveals Low Incidence of Off-target Mutations in the Genetically Edited Small Ruminants”, 2nd Large Animal Genetic Engineering Summit, Park City, Jun 2018 (大会报告)
  “Heritable multiplex gene editing via CRISPR/Cas9 exhibits low incidence of off-target mutations in sheep and goats”, Netherlands Commission on Genetic Modification, 2017, Rotterdam (大会报告)
  “Heritable multiplex gene editing via CRISPR/Cas9 exhibits no detectable genome-wide off-target effects in sheep”, 35thISAG, 2016, Salt Lake City, USA (大会报告)
  “Multiplex genome editing in goats and sheep via the CRISPR/Cas9 system”, 3rdPAG ASIA. 2016, Singapore (大会报告)
  
  



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