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西北农林科技大学化学与药学院导师教师师资介绍简介-汤江江

本站小编 Free考研考试/2021-07-07

一、个人简介
  汤江江,副教授(2015.01),硕士生导师。
  教育背景:2002.9–2011.6,兰州大学 本硕博,获理学博士学位,导师周波教授;
  博士后经历:2011.12–2014.12,西北农林科技大学 化学生物学,合作导师 高锦明教授。
  二、科研课题
  先后主持(时间顺序):
  南开大学元素有机化学国家重点实验室开放基金1项;
  国家自然科学基金青年项目1项,应急管理项目1项;
  陕西省自然科学基金青年人才项目1项.
  三、研究领域
  1. 天然活性萜类物质的多样性合成、构效关系和靶点识别;
  2. 基于作用机制(靶点)明晰的药物设计与合成。
  四、开设课程
  《有机化学》、《有机化学(双语)》、《有机化学实验》。
  五、主要科研成果与学术论文
  以第一作者或通讯作者发表的学术论文:
  15. HanYu, GuoyongDai, Qiu-RuiHe, Tang, J. J. *, Enantioselective synthesis and evaluation of 4-styryldihydropyrimidin-2-thiones as anti-proliferative agents. Med. Chem. Res. 2017, doi:10.1007/s00044-017-1790-4. (IF2015: 1.436)
  14. Han Y. Y.; Tang J. J. *; Gao R. F.; Guo X.; Lei M.*; Gao J. M., A new semisynthetic 1-O-acetyl-6-O-lauroylbritannilactone induces apoptosis of human laryngocarcinoma cells through p53-dependent pathway. Toxicol. In Vitro 2016, 35 : 112-120. (IF2015: 3.338)
  13. Fan N.-J.; He Q.-R.; Duan M.; Bai Y.-B.; Tang J.-J. *, Synthesis and antiproliferative activity of D-ring substituted steroidal benzamidothiazoles. Steroids 2016, 112 : 103-108. (IF2015: 2.513)
  12. Mu H.; Liu Q.; Niu H.; Wang D.; Tang J.*; Duan J.* Autophagy Promotes DNA-protein Crosslink Clearance. Mutat. Res-Gen. Tox. En. 2016, 797 : 21-25. (IF2015: 2.254)
  11. Xiang P.; Guo X.; Han Y.-Y.; Gao J.-M.; Tang J.-J.* Cytotoxic and Pro-apoptotic Activities of Sesquiterpene Lactones from Inula Britannica . Nat. Prod. Commun. 2016, 11: 7-10. (IF2015: 0.884)
  10. Guo X.; Gao J.-M.; Tang J. J. * ( S )-4-[(3a R ,4 S ,7a R )-4-Methoxy-6-methyl-3-methylene- 2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl]pentyl Acetate. Molbank 2016, 2016, M890.
  9. Tang J.-J.; Li G.; Gao J.-M.* Synthesis and cytotoxicity of novel steroidal C-20 oxime ester derivatives from 16-DPA. Ar. J. Chem. 2015, DOI:10.1016/j.arabjc.2014.12.032. (IF2014: 3.725)
  8. Fan N.-J.; Wei S.-P.; Gao J.-M.; Tang J.-J.* Potential Insecticidal Activity of Steroidal C-17 Pyrazolinyl Derivatives. J. Braz. Chem. Soc. 2015, 26: 389-392. (IF2014: 1.129)
  7. Dong S.;Tang J.-J.*; Chang C.-C.; Tian J.-M.; Guo J.-T.; Zhang Q.; Li H.;Gao J.-M.* Semisynthesis and in vitro cytotoxic evaluation of new analogues of 1- O -acetylbritannilactone, a sesquiterpene from Inula Britannica . Eur. J. Med. Chem. 2014, 80: 71-82. (IF2015: 3.902)
  6. Tang J.-J.; Dong S.;Han Y.-Y.; Lei M.; Gao J.-M.* Synthesis of 1- O -acetylbritannilactone Analogues from Inula britannica and in vitro Evaluation of their Anticancer Potential. MedChemComm . 2014, 10: 1584-1589. (IF2014: 2.495, co-first author)
  5. Tang J.-J.; Zhang F.-Y.; Wang D.-M.; Tian J.-M.; Dong S.; Gao J.-M.* Semisynthesis and Antifeedant Activity of New Derivatives of Dihydro-b-Agarofuran, a Sesquiterpene from Parnassia wightiana . Int. J. Mol. Sci. 2013 , 14: 19484-19493. (IF2014: 2.862, co-first author)
  4. Fan N.-J.; Tang J.-J.; Zhang Q.-Z.; Gao J.-M.* Synthesis and cytotoxic activity of some novel steroidal C-17 pyrazolinyl derivatives. Eur. J. Med. Chem. 2013, 69: 182-190. (IF2014: 3.447, co-first author)
  3. Tang J.-J.; Fan G.-J.; Dai F.; Ding D.-J.; Wang Q.; Lu D.-L.; Li R.-R.; Li X.-Z.; Hu L.-M.; Jin X.-L.; Zhou B. * Finding more active antioxidants and cancer chemoprevention agents by elongating the conjugated links of resveratrol. Free Radic. Biol. Med . 2011, 55: 1447-1457. (IF2014: 5.736)
  2. 范宁娟, 汤江江*. 4-酰氧基黄体酮衍生物的合成及其细胞毒活性研究. 合成化学 2016, 24(9): 763-767. (核心)
  1. 范宁娟, 王长如, 汤江江*, 高锦明. 氯化亚锡还原法合成4’-氨基黄体酮类苯亚甲基衍生物. 应用化学 2014, 31: 520-523. (核心)
  六、联系方式
  通讯地址:西北农林科技大学化学与药学院 理科大楼C212
  邮编:712100
  电话:**
  邮箱:tangjiang11@nwafu.edu.cn; kelvintang02@163.com


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