王筱冰,女,博士,副教授,硕士生导师。主要从事细胞生物学、肿瘤分子生物学、超声医学方面教学科研工作。目前主持国家自然科学基金青年项目、陕西省自然科学基金项目、中央高校科研项目各1项,参与省部级以上科研项目多项,作为主要完成人荣获陕西省科学技术二等奖1项,在UltrasoundinMedicine&Biology、ToxicologyinVitro、CancerChemotherapy&Pharmacology、CancerBiotherapy&Radiopharmaceuticals、Ultrasonics、Chemotherapy等SCI源期刊上发表期刊论文40多篇。
科研项目:
- 国家自然科学基金青年项目:超声激活原卟啉IX诱导人白血病细胞凋亡和细胞自噬性死亡的机制探讨(**),2011.1-2013.12,主持人。
陕西省自然科学基金项目:p38MAPK信号通路对声动力诱导乳腺癌细胞死亡的分子调控作用(2011JQ4012),2012.1-2013.12,主持人。
中央高校基本科研业务费专项资金项目:ROS在声光联合疗法诱导乳腺癌细胞线粒体自噬中的信号调控(GK**),2012.1-2013.12,主持人。
陕西师范大学优秀博士论文资助项目:原卟啉IX-声动力学疗法抗肿瘤效应的实验研究(X2007YB05),2008-2010,主持人。
国家自然科学基金青年项目:声动力学疗法介导白血病细胞的死亡模式及其机制研究(**),2010.1-2012.12,参加人。
教育部高等学校博士学科点专项科研基金:声动力诱导乳腺癌细胞自噬性死亡机制研究(**006),2011.1-2013.12,参加人。
陕西省自然科学基金项目:磁场联合抗癌药物抑制肿瘤细胞生长的细胞分子生物学机制(2012JQ4003),2013.1-2014.12,参加人。
中央高校基本科研业务费专项资金项目:MAPK信号通路在Ce6-SDT诱导人白血病细胞死亡机制中的作用(GK**),2013.1-2014.12,参加人。
- HaipingWang,XiaobingWang*,ShangliangZhang,PanWang,KunZhang,QuanhongLiu*.AnovelsensitizerDVDMS,triggersmitochondrialdependentapoptosisinEca-109cellsviaROSproduction.InternationalJournalofNanomedicine.(Accept)
XiaominSu,YanChen,XiaobingWang*,YuanWang,PanWang,LongLi,QuanhongLiu*.PpIXinducesmitochondria-relatedapoptosisinmurineleukemiaL1210cells.DrugandChemicalToxicology,2013,doi:10.3109/**.2013.866135.
QingLi,QuanhongLiu,PanWang,XiaolanFeng,HaipingWang,XiaobingWang*.TheeffectsofCe6-mediatedsono-photodynamictherapyoncellmigration,apoptosisandautophagyinmousemammary4T1cellline.Ultrasonics,2014,54(4):981-989.
XiaominSu,YixiangLi,PanWang,XiaobingWang*,QuanhongLiu.ProtoporphyrinIX-mediatedsonodynamicactioninducesapoptosisofK562cells.Ultrasonics,2014,54(1):275-284.
CaifengLi,KunZhang*,PanWang,JianminHu,QuanhongLiu,XiaobingWang*.SonodynamicantitumoreffectofanovelsonosensitizeronS180solidtumor.Biopharmaceutics&DrugDisposition,2014,35(1):50-59.
HaipingWang,QuanhongLiu,KunZhang,PanWang,QinXue,LongLi,XiaobingWang*.ComparisonbetweensonodynamicandphotodynamiceffectonMDA-MB-231cells.JournalofPhotochemistryandPhotobiologyB-Biology,2013,127:182-191.
ShuangYang,PanWang,XiaobingWang*,KunZhang,XingZhang,QuanhongLiu*.Efficacyofcombinedtherapywithpaclitaxelandlow-levelultrasoundinhumanchronicmyelogenousleukemiacelllineK562.JournalofDrugTargeting,2013,21(9):874-884.
XiaobingWang,PanWang,KunZhang,XiaominSu,JieHou,QuanhongLiu.InitiationofautophagyandapoptosisbysonodynamictherapyinmurineleukemiaL1210cells.ToxicologyinVitro,2013,27(4):1247-1259.
YixiangLi,PanWang,PingZhao,SijiaZhu,XiaobingWang*,QuanhongLiu.Apoptosisinducedbysonodynamictreatmentbyprotoporphyrinixonmda-mb-231cells.Ultrasonics,2012,52(4):490-496.
XiaobingWang,YuWang,PanWang,XiaoxiaCheng,QuanhongLiu.Sonodynamicallyinducedanti-tumoreffectwithprotoporphyrinixonhepatoma-22solidtumor.Ultrasonics,2011,51(5):539-546.
XiaobingWang,QuanhongLiu,NaMi,PanWang,WeiTang,XianghongZhao,XiujuanLi.Sonodynamicallyinducedapoptosisbyprotoporphyrinixonhepatoma-22cellsinvitro.UltrasoundinMedicine&Biology,2010,36(4):667-676.
XiaobingWang,QuanhongLiu,ZhezhiWang,PanWang,PingZhao,XianghongZhao,LiangYang,YixiangLi.Roleofautophagyinsonodynamictherapy-inducedcytotoxicityins180cells.UltrasoundinMedicine&Biology,2010,36(11):1933-1946.
XiaobingWang,PanWang,WanyanTong,QuanhongLiu.Comparisonofpharmacokinetics,intracellularlocalizationsandsonodynamicefficacyofendogenousandexogenousprotoporphyrinixinsarcoma180cells.Ultrasonics,2010,50(8):803-810.
XiaobingWang,QuanhongLiu,ZhezhiWang,PanWang,QiaoHao,ChendiLi.Bioeffectsoflow-energycontinuousultrasoundonisolatedsarcoma180cells.Chemotherapy,2009,55(4):253-261.
XiaobingWang,QuanhongLiu,PanWang,ZhezhiWang,WanyanTong,BoZhu,YuanWang,ChendiLi.Comparisonsamongsensitivitiesofdifferenttumorcellstofocusedultrasoundinvitro.Ultrasonics,2009,49(6-7):558-564.
XiaobingWang,QuanhongLiu,PanWang,KunZhang,WeiTang,BaoluWang.Enhancementofapoptosisbysonodynamictherapywithprotoporphyrinixinisolatesarcoma180cells.CancerBiotherapy&Radiopharmaceuticals,2008,23(2):238-246.
XiaobingWang,QuanhongLiu,PanWang,WeiTang,QiaoHao.Studyofcellkillingeffectons180byultrasoundactivatingprotoporphyrinix.Ultrasonics,2008,48(2):135-140.
QuanhongLiu,XiaobingWang,PanWang,LinaXiao,QiaoHao.Comparisonbetweensonodynamiceffectwithprotoporphyrinixandhematoporphyrinonsarcoma180.CancerChemotherapyandPharmacology,2007,60(5):671-680.
QuanhongLiu,XiaobingWang,PanWang,LinaXiao.Sonodynamicantitumoreffectofprotoporphyrinixdisodiumsaltons180solidtumor.Chemotherapy,2007,53(6):429-436.
QuanhongLiu,XiaobingWang,PanWang,HaoQi,KunZhang,LinaXiao.Sonodynamiceffectsofprotoporphyrinixdisodiumsaltonisolatedsarcoma180cells.Ultrasonics2006;45(1-4):56-60.
联系方式:**
电子邮箱:wangxiaobing@snnu.edu.cn