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基本信息 The basic information
姓名: 邓旭东

学院: 生命学院


学历: 博士研究生毕业

学位: 博士


职称: 副教授

职务:


学科: 生物医学工程


邮箱: dengxd@nwpu.edu.cn




工作经历 Work Experience
2016.09 西北工业大学生命学院副教授

2019.06 西北工业大学生命学院副教授，硕士生导师


Sep 2016 Associate Professor, School of Life Sciences, Northwestern Polytechnical University.
June 2019 Associate Professor, Master's Supervisor,School of Life Sciences, Northwestern Polytechnical University.



教育经历 Education Experience
2005-2009 浙江大学化学工程与生物工程学系 生物工程 本科
2009-2012 浙江大学化学工程与生物工程学系 生物化工 硕士
2012-2016 加拿大麦克马斯特大学化学工程系 博士


2009 Bechelor in Bioengineering, Department of Chemical and Biological Engineering, Zhejiang University.
2012 Master in Biochemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University.
2016 PhD, Department of Chemical Engineering, McMaster University.



教育教学 Education And Teaching
本科生课程
2017-2018学年春季学期、2019-2020学年春季学期纳米生物医学技术
2018-2019学年秋季学期、2019-2020学年秋季学期、2020-2021学年秋季学期生物专业英语（英）
2019-2020学年秋季学期、2020-2021学年秋季学期生物技术（英）
2019-2020学年秋季学期、2019-2020学年春季学期、2020-2021学年秋季学期文献检索与论文写作
2019-2020学年春季学期 认识实习


Undergraduate Courses
2017-2018 Spring,2019-2020 Spring, Nano Biomedical Technology
2018-2019 Autumn,2019-2020 Autumn, 2020-2021 Autumn, English for Biology (English)
2019-2020 Autumn, 2020-2021 Autumn, Biotechnology (English)
2019-2020 Autumn, 2019-2020 Spring, 2020-2021 Autumn, Information Retrieval and Academic Writing
2019-2020 Spring, Cognitive Practice


研究生课程
2017-2018学年春季学期 2018-2019学年春季学期 2019-2020学年春季学期纳米生物技术导论


Graduate Courses
2017-2018 Spring, 2018-2019 Spring, 2019-2020 Spring,Introduction to Nanobiotechnology


教改项目
西北工业大学2020年研究生培养质量提升项目（第一期）-研究生实践能力提升计划（第一批），06180-20GH010201，专业学位案例库-新型消杀试剂的研发及在新冠病毒防疫中的应用。
西北工业大学2020年研究生培养质量提升项目（第一期）-生命学院2020年研究生教育教学改革项目（第二批），06180-20GZ210101，专业学位案例库-新型消杀试剂的研发及在新冠病毒防疫中的应用。


教改论文
田野，邓旭东，高永光，骞爱荣.生物化学课程全英文教学的实践探索，长春师范大学学报，2020，39(2):160-162.


社会实践
2019 共青团中央“深度扶贫地区青春行”全国大学生暑期社会实践专项活动实践团队（指导教师）
2019 西北工业大学暑期社会实践校级优秀实践队特等奖，优秀指导教师，优秀调研报告一等奖
2020 西北工业大学暑期社会实践优秀指导教师，优秀调研报告二等奖



招生信息 Admission Information
硕士学位研究生招生专业：
083100 生物医学工程
0860 生物与医药


Recruit master students in Biomedical Engineering and Biology & Medicine.


荣誉获奖 Awards Information
2016 国家优秀自费留学生奖学金Chinese Government Award for Outstanding Self-Financed Students Abroad
2020 第二十二届中国国际高新技术成果交易会（CHINA HI-TECH FAIR 2020 ）优秀产品奖：面向新冠病毒公共场所消杀需求的安全高效消毒剂

2020 西北工业大学抗击疫情先进个人



科学研究 Scientific Research
主持项目
1.主持国家自然科学基金青年项目，**，高分子接枝TEMPO介导酶催化含伯醇生物材料的表面氧化，2019.1-2021.12，22.7万元；
2.主持陕西省留学人员科技活动择优资助项目，**，水凝胶类材料的表面氧化与多功能化修饰，2018-2019，3万元；
3.主持中央高校基本科研业务费-西北工业大学新进教师科研启动费，**OQD039，基于互穿聚合物网络的高强度快速自修复水凝胶，2017.1-2018.12，20万元。

4.主持中央高校基本科研业务费-自由探索类项目，**smxy003，新型水溶性高分子核酸递送体系的设计及其在RNA治疗中的应用，2019.7-2021.7，16万元。
5. 主持中央高校基本科研业务费-新冠肺炎疫情防控科研攻关应急项目，**KJYQFK009，面向新型冠状病毒公共场所消杀需求的安全高效消毒剂开发，2020.3-2020.12，8万元。


Fundings
1.National Natural Science Foundation of China (Grant No. **). 2019.1-2021.12, RMB 227000
2.Technology Foundation for Selected Overseas Chinese Scholar in Shaanxi Province (Grant No. **). 2018-2019, RMB 30000
3. The Fundamental Research Funds for the Central Universities (Grant No. **OQD039).2017.1-2018.12, RMB 200000
4.The Fundamental Research Funds for the Central Universities(Grant No. **smxy003). 2019.7-2021.7, RMB 160000
5.The Fundamental Research Funds for the Central Universities(Grant No. **KJYQFK009). 2020.3-2020.12, RMB 80000


参与项目
1. 参与国家自然科学基金面上项目，**，面相药物体外评价的肠肝组织工程反应器构建研究。
2. 参与国家自然科学基金面上项目，**，基于组织工程反应器的生物表面活性剂鼠李糖脂作用机制研究及安全性评价。
3. 参与军队后勤科研计划项目-重点项目，*********，×××××与×××××食品关键技术研究。
4. 参与陕西省创新能力支撑计划-科技创新团队计划，2020TD-042，医用蛋白质制备与应用创新团队。
5. 参与陕西省创新能力支撑计划-国际合作基地，2019GHJD-01，柔性电子与健康科学国际联合研究中心。
6. 参与中央高校基本科研业务费-“一带一路”及校际重要合作伙伴科技合作种子基金，**ghxm017，通过miR-4458靶向胶原蛋白COL11A1参与乳腺癌发生的机理研究。



学术成果 Academic Achievements
截至2021年5月，在J. Am. Chem. Soc., ACS Appl. Mat. Interfaces, Biomacromolecules, Appl. Surf. Sci., Polym. Chem. 等杂志发表SCI论文24篇，其中第一或通讯作者14篇，Web of Science累计被引339次，H-index=11（Google Scholar Citations=419, h-index=12, i10-index=15）；作为第一发明人申请中国发明专利4项，授权1项；授权美国发明专利1 项；详细列表如下：


Journal Publications
[24] Zhang C-Y*, Zhao S-Q, Zhang S-L, Luo L-H, Liu D-C, Ding W-H, Fu D-J, Deng X-D, Yin D-C. Database Study on the Expression and Purification of Membrane Proteins. Protein & Peptide Letters. 2021, DOI: 10.2174/34
[23] Zhang T-D^#, Chen L-L^#, Lin W-J, Shi W-P, Wang J-Q, Zhang C-Y, Guo W-H, Deng X*, Yin D-C*. Searching for conditions of protein self-assembly by protein crystallization screening method.Applied Microbiology and Biotechnology. 2021, 105: 2759-2773.
[22] He J, Li D-W, He F-L, Liu Y-Y, Liu Y-L, Zhang C-Y, Ren F, Ye Y-J, Deng X-D, Yin D-C*. A study of degradation behaviour and biocompatibility of Zn-Fe alloy prepared by electrodeposition. Materials Science and Engineering: C. 2020, 117: 111295.

[21] Zhang T-D^#, Deng X^#*, Wang Y-F, Wang X-T, Zhang X, Chen L-L, Cao X, Zhang Y-Z, Zhang C-Y, Zheng X*, Yin D-C*. Layer-by-layer coating of polyvinylamine and dopamine-modified hyaluronic acid inhibits the growth of bacteria and tumor cell lines on the surface of materials. Applied Surface Science. 2020, 530: 147197.
[20] Song X^#, Deng X^#, Wang Q^#, Tian J, He F-L, Hu H-Y, Tian W*. Self-Assembling Morphology-Tunable Single-Component Supramolecular Antibiotic for Enhanced Antibacterial Manipulation. Polymer Chemistry. 2020, 11: 102-111.
[19] Li J, Yan E-K, Liu Y, Wu Z-Q, Liu Y-L, Hou H, Zhang C-Y, Lu Q-Q, Deng X-D, Yin D-C*. Comparison of the Quality of Protein Crystals Grown by CLPC Seeds Method. Crystals. 2019, 9(10):501
[18] He F-L^#, Deng X^#, Zhou Y-Q, ZhangT-D, Liu Y-L, Ye Y-J*, Yin D-C*. Controlled release of antibiotics frompoly-ε-caprolactone/polyethylene glycol wound dressing fabricated bydirect-writing melt electrospinning. Polymersfor Advanced Technologies. 2019, 30(2): 425-434.
[17] Hou H^#*, Shi M^#, ChenZ-H, Ahmad F, Liu Y, Yan E-K, Luo C, Li J, Zhu C-L, Deng X-D*, Yin D-C*. Ahigh-performance protein crystallization plate pre-embedded with crosslinkedprotein microcrystals as seeds. CrystEngComm.2018, 20: 4713-4718. (Journal Inside FrontCover)
[16] Yin J^#*, Deng X^#, Zhang J, Lin J.Current Understanding of Interactions between Nanoparticles and ABCTransporters in Cancer Cells. CurrentMedicinal Chemistry. 2018. 25(42): 5930-5944.
[15] Li D-W^#, He J^#, HeF-L, Liu Y-L, Liu Y-Y, Ye Y-J, Deng X*,Yin D-C*. Silk fibroin/chitosan thin film promotes osteogenic and adipogenicdifferentiation of rat bone marrow-derived mesenchymal stem cells. Journal of Biomaterials Applications.2018, 32(9): 1164-1173.
[14] He F-L^#,Li D-W^#, He J, Liu Y-Y, Ahmad F, Liu Y-L, Deng X, Ye Y-J*, Yin D-C*. A novel layer-structured scaffold withlarge pore sizes suitable for 3D cell culture prepared by near-fieldelectrospinning. Materials Science andEngineering: C. 2018, 86: 18-27.
[13] DengX, Attalla R, Sadowski LP, Chen M, Majcher MJ, Urosev I, Yin D-C,Selvaganapathy PR, Filipe CD*, Hoare T*. Autonomously Self-Adhesive Hydrogelsas Building Blocks for Additive Manufacturing. Biomacromolecules. 2018, 19(1): 62-70. (Journal Front Cover)
[12]Li D-W^#, He F-L^#, He J, Deng X, Liu Y-L, Liu Y-Y, Ye Y-J, Yin D-C*. From 2D to 3D: Themorphology, proliferation and differentiation of MC3T3-E1 on silkfibroin/chitosan matrices. Carbohydrate Polymers.2017, 178: 69-77.
[11]He F-L^#, He J^#, DengX, Li D-W, Ahmad F, Liu Y-Y, Liu Y-L, Ye Y-J, Zhang C-Y, Yin D-C*.Investigation of the effects of melt electrospinning parameters on thedirect-writing fiber size using orthogonal design. Journal of Physics D: Applied Physics. 2017, 50(42): 425601.
[10] Li D-W^#,Lei X^#, He F-L, He J, Liu Y-L, Ye Y-J, Deng X*, Duan E, Yin D-C*. Silk fibroin/chitosan scaffold withtunable properties and low inflammatory response assists the differentiation ofbone marrow mesenchymal stem cells. InternationalJournal of Biological Macromolecules. 2017, 105: 584-597.
[9]Yue C, Sun H, Liu W-J, Deng X, GuanB, Zhang X, Yang P*. Environmentally Benign, Rapid and Selective Extraction ofGold from Ores and Waste Electronic Materials. Angewandte Chemie International Edition. 2017, 56(32): 9331-9335.
[8] Deng X, Korogiannaki M, Rastegari B,Zhang J, Chen M, Fu Q, Sheardown H, Filipe CD*, Hoare T*. “Click”chemistry-tethered hyaluronic acid-based contact lens coatings improve lenswettability and lower protein adsorption. ACSApplied Materials & Interfaces. 2016, 8(34): 22064-22073.
[7]Chen M, Yin H, Bai P, Miao P, Deng X,Xu Y, Hu J, Yin J*. ABC transporters affect the elimination and toxicity ofCdTe quantum dots in liver and kidney cells. Toxicology and Applied Pharmacology. 2016, 303: 11-20.
[6]Yin H, Bai P, Miao P, Chen M, Hu J, DengX, Yin J*. Functional expressions of adenosine triphosphate‐binding cassette transporters during thedevelopment of zebrafish embryos and their effects on the detoxification ofcadmium chloride and β‐naphthoflavone.Journal of Applied Toxicology. 2016,36(7): 925-935.
[5] Deng X, Chen M, Fu Q, Smeets NM, Xu F,Zhang Z, Filipe CD*, Hoare T*. A highly sensitive immunosorbent assay based onbiotinylated graphene oxide and the quartz crystal microbalance. ACS Applied Materials & Interfaces.2016, 8(3): 1893-1902.
[4] Deng X, Smeets NM, Sicard Cm, Wang J,Brennan JD, Filipe CD*, Hoare T*. Poly (oligoethylene glycol methacrylate)Dip-Coating: Turning Cellulose Paper into a Protein-Repellent Platform forBiosensors. Journal of the AmericanChemical Society. 2014, 136(37): 12852-12855.
[3]Xu Y, Zhang Z, Ali MM, Sauder J, Deng X,Giang K, Aguirre SD, Pelton R, Li Y*, Filipe CD*. Turning Tryptophanase intoOdor‐GeneratingBiosensors. Angewandte ChemieInternational Edition. 2014, 53(10): 2620-2622.
[2] Deng X, Shen C, Meng Q*. Screening ofherbal components for attenuating amiodarone-induced hepatotoxicity ongel-entrapped rat hepatocytes. Drug and ChemicalToxicology. 2014, 37(1): 100-106.
[1] Deng X, Zhang G, Shen C, Yin J, Meng Q*.Hollow fiber culture accelerates differentiation of Caco-2 cells. Applied Microbiology and Biotechnology.2013, 97(15): 6943-6955.


Web of Science ResearcherIDN-5407-2015
ORCID0000-0002-4463-9581
Google Scholar Xudong Deng


专利 Patent
[1]Hoare T, Bakaic E, Smeets NM, Deng X.Poly (oligoethylene glycol methacrylate) hydrogel compositions, and methods ofuse thereof. 2016. US**B2; 2019. USA1.
[2]邓旭东，张熙，尹大川，王雪霆，张托弟，贺聪。一种水凝胶材料催化氧化与功能化修饰的方法。专利号：ZL8.X授权公告号：CNB
[3] 邓旭东，田野，尹大川，骞爱荣，高永光，王雪，李瑞云，张托弟。阳离子聚乙烯胺线形高分子作为转基因载体的应用。专利申请号：CN9.8专利公开号：CNA
[4] 邓旭东，尹大川，张连兵。一种复合季铵盐消毒剂。专利申请号：CN1.3 专利公开号：CNA






社会兼职 Social Appointments
担任 ACS Nano, Acta Biomaterialia, Carbohydrate Polymers, Soft Matter, Colloids and Surfaces B: Biointerfaces, European Polymer Journal, Progress in Organic Coatings,Analytical and Bioanalytical Chemistry, Journal of Biomaterials Science: Polymer Edition, Journal of Biochemical and Molecular Toxicology等SCI期刊审稿人
担任Frontiers in Bioengineering and Biotechnology期刊专题编辑
中国生物材料学会会员
美国化学会（ACS）会员，美国化学会高分子材料科学与工程分会（ACS-PMSE）会员
西安欧美同学会会员，西安欧美同学会生物医药专业委员会委员
陕西省药理学会生化与分子药理学专业委员会委员


Journal Referee of ACS Nano, Acta Biomaterialia, Carbohydrate Polymers, Soft Matter, Colloids and Surfaces B: Biointerfaces, European Polymer Journal, Progress in Organic Coatings,Analytical and Bioanalytical Chemistry,Journal of Biomaterials Science: Polymer Edition, Journal of Biochemical and Molecular Toxicology etc.
Topic Editor ofFrontiers in Bioengineering and Biotechnology
Member of Chinese Society for Biomaterials (CSBM)
Member of American Chemical Society (ACS)
Member of ACS division: Polymeric Materials: Science & Engineering (PMSE)
Member of Western Returned Scholars Association (WRSA, Xi'an)
Committee member of WRSA Xi'an Biomedical Committee



English Version