姓名：张洪星
职称：讲师
联系方式：hxzhang4714@sxu.edu.cn
介绍：
张洪星，理学博士，长期从事荧光染料及荧光探针的开发，主要研究兴趣为新型荧光染料的合成、活性硫化物（ROS）和活性氧/氮化物（ROS/RNS）的传感及生物影像研究，在JACS, Chem.Sci., Biomaterials, Chem. Commun.等国际著名期刊共发表SCI论文10篇，被引频次总计892次。
学习与工作经历：
2018/07 – 至今，山西大学，化学化工学院
2015/09 – 2018/07，山西大学，博士
2012/09 – 2015/07，山西大学，硕士
2008/09 – 2012/07，山西大学，学士
讲授课程：有机化学
研究方向：分子识别与生物传感
主持科研项目：
山西省高等学校创新人才支持计划，2019-2021，主持
代表性论文：
1．Jing Liu, Mengxing Liu, Hongxing Zhang, Xuehong Wei, Juanjuan Wang, Ming Xian and Wei Guo*, Exploring cysteine regulation in cancer cell survival with a highly specific “Lock and Key” fluorescent probe for cysteine, Chemical Science, 2019, 10, 10065.
2．Hongxing Zhang, Jing Liu, Bo Hu, Linfang Wang, Z Yang, Xu Han, Juanjuan Wang, Wei Bai, Wei Guo*, Dual-Channel Fluorescence Diagnosis of Cancer Cells/Tissues Assisted by OATP Transporters and Cysteine/Glutathione, Chemical Science, 2018, 9, 3209.
3．Hongxing Zhang, Jing Liu, Linfang Wang, Minjia Sun, Xiaohan Yan, Juanjuan Wang, Jianping Guo, Wei Guo*, Amino-Si-rhodamines: A new class of two-photon fluorescent dyes with intrinsic targeting ability for lysosomes. Biomaterials, 2018, 158, 10.
4．Hongxing Zhang, Jing Liu, Chenlu Liu, Pengcheng Yu, Minjia Sun, Xiaohan Yan, Jian-Ping Guo*, Wei Guo,* Imaging lysosomal highly reactive oxygen species and lighting up cancer cells and tumors enabled by a Si-rhodamine-based near infrared fluorescent probe, Biomaterials, 2017, 133, 60.
5．Jing Liu, Yuan-Qiang Sun, Hongxing Zhang, Heping Shi, Yawei Shi, and Wei Guo.* Sulfone-Rhodamines: A New Class of Near-Infrared Fluorescent Dyes for Bioimaging, ACS Appl. Mater. Interfaces. 2016, 8, 22953.
6．Hongxing Zhang, Jing Liu, Yuan-Qiang Sun, Yingying Huo, Yaohua Li, Weizhi Liu, Xiao Wu, Nishu Zhu, Yawei Shi and Wei Guo*, A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity, Chem. Commun., 2015, 51, 2721.
7．Yuan-Qiang Sun, Jing Liu, Hongxing Zhang, Yingying Huo, Xin Lv, Yawei Shi, and Wei Guo*, A Mitochondria-Targetable Fluorescent Probe for Dual-Channel NO Imaging Assisted by Intracellular Cysteine and Glutathione. J. Am. Chem. Soc., 2014, 136, 12520.
8．Jing Liu，Yuan-Qiang Sun，YingYing Huo，HongXing Zhang, LinFang Wang, Pei Zhang, Dan Song, YaWei Shi, Wei Guo*, Simultaneous Fluorescence Sensing of Cys and GSH from Different Emission Channels, J. Am. Chem. Soc. 2014,136, 574.
9．Jing Liu，Yuan-Qiang Sun, HongXing Zhang, YingYing Huo, YaWei Shi, Wei Guo*, Simultaneous Fluorescent Imaging of Cys/Hcy and GSH from Different Emission Channels, Chemical Science, 2014, 5, 3183.
10．Jing Liu, Yuan-Qiang Sun, Hongxing Zhang, Yingying Huo, Yawei Shi, Heping Shi and Wei Guo*, A carboxylic acid-functionalized coumarinhemicyanine fluorescent dye and its application to construct a fluorescent probe for selective detection of cysteine over homocysteine and glutathione, RSC Advances, 2014, 4, 64542.