姓名：胡晓珂
性别：女
出生年与：1977年2月
学科专业：环境微生物学
专业技术职称：研究员
行政职务：
联系电话：**
Email：xkhu@yic.ac.cn

学习与工作经历

1995年9月至1999年7月，中国海洋大学药物与食品研究所，药物化学 学士；
1999年9月至2004年7月， 中国海洋大学药物与食品研究所，水产品加工与贮藏 博士；
2004年10月至2011年11月，分别在美国Jackson State University和Louisiana State University进行研究工作；
2011年11月至今，“百人计划”引进到中科院海岸带研究所，研究员。


研究领域（方向）

海岸带环境中石油和持久性有机污染物污染的降解和修复
海岸带环境中病原微生物的检测和溯源技术的建立




承担的科研项目

中科院“百人计划”
烟台市科技发展项目，烟台海岸带持久性有机污染物的微生物修复研究，**，主持




代表性论文（著作、专利）


Benson G. Ongarora, Xiaoke Hu, Susan D. Verberne-Sutton, Jayne C. Garno, Gra?a H. Vicente. “Syntheses and Photodynamic Activity of Pegylated Cationic Zn(II)- Phthalocyanines in HEp2 Cells”. Theranostics on Porphyrins and Phthalocyanines. In press.TimsyUppal, Xiaoke Hu, Frank R. Fronczek, Stephanie Maschek, PetiaBobadova-Parvanova, M. Graca H. Vicente. (2012) “Synthesis, Computational Modeling, and Properties of Benzo-Appended BODIPYs”. Chemistry-A European Journal. 18: 3893-3905.Benson G. Ongarora, Xiaoke Hu, Hairong Li, Frank R. Fronczek, M. Graca H. Vicente. (2012) Syntheses and properties of trimethylaminophenoxy-substituted Zn(II)-phthalocyanines. Medchemcomm. 3: 179-194.Martha Sibrian-Vazquez, Xiaoke Hu, Timothy J. Jensen, Graca H. Vicente. (2012) “Synthesis and cellular studies of PPIX-homing peptide conjugates”. Journal of Porphyrins and Phthalocyanines. 16, 603-615.Benson G. Ongarora, Krystal R. Fontenot, Xiaoke Hu, InderSehgal, Seetharama D. Satyanarayana-Jois, and M. Gra?a H. Vicente. (2012) “Phthalocyanine–Peptide Conjugates for Epidermal Growth Factor Receptor Targeting”. J. Med. Chem. 55 (8), pp 3725–3738.N.V.S. Dinesh K. Bhupathiraju, Vijay Gottumukkala, ErhongHao, Xiaoke Hu, Frank R. Fronczek, David G. Baker, Nobuko Wakamatsu, M. Gra?a H. Vicente. (2012)“Synthesis and toxicity of cobaltabisdicarbollide-containing porphyrins of high boron content”. Journal of Porphyrins and Phthalocyanines.15:973-983Jialong Yang, Xiumei Wei, JieXu, Dinglong Yang, Xiangquan Liu, Jianmin Yang, Jinghui Fang, Xiaoke Hu. (2012) “A sigma-class glutathione S-transferase from Solengrandis that responded to microorganism glycan and organic contaminants”. Fish & Shellfish Immunology. 32: 1198-1204.Jialong Yang, Xiumei Wei, Xiangquan Liu, JieXu, Dinglong Yang, Jianmin Yang, Jinghui Fang, Xiaoke Hu. (2012) “Cloning and transcriptional analysis of two sialic acid-binding lectins (SABLs) from razor clam Solengrandis”. Fish & Shellfish Immunology. 32: 578-585.Samuel H. Lahasky, Xiaoke Hu, Donghui Zhang. (2012) “ThermoresponsivePoly(α-peptoid)s: Tuning the Cloud Point Temperatures by Composition and Architecture”. ACS Macro Letters. 1, 580-584.R.G. WarunaJinadasa, Xiaoke Hu, M. Graca H. Vicente, Kevin M. Smith. (2011) “Syntheses and Cellular Investigations of 17³-, 15²-, and 13¹-Amino Acid Derivatives of Chlorin e₆”. Journal of Medicinal Chemistry. 54: 7464-7476.Xiaoke Hu, ZhiminXu. (2011) “Isolation Characterization of Bioactive Compounds in Fruits and Cereals.” Fruit and Cereal Bioactives. Sources, Chemistry, and Applications, 319-336.Tomasz PuzynBakhtiyorRasulev, AgnieszkaGajewicz, Xiaoke Hu, Thabitha P. Dasari, Andrea Michalkova, Huey-Min Hwang, AndreyToropov, DanutaLeszcznska, Jerzy Leszczynski. (2011) “Minimizing risk of nanotechnology: Nano-QSAR predictions before manufacturing.” Nature Nanotechnology 6:175-178.Lijuan Jiao, Changjiang Yu, TimsyUppal, Mingming Liu, Yan Li, Yunyou Zhou, ErhongHao, Xiaoke Hu, M. Graca H. Vincente. (2010) “Long wavelength red fluorescent dyes from 3,5-diiodo-BODIPYs. ” Organic &Biomolecular Chemistry. 8: 2517-2519.Xiaoke Hu, Sean Cook, Peng Wang, Huey-min Hwang, Xi Liu, Quinton L. Williams. (2010) “In Vitro eva luation of cytotoxicity of engineered carbon nanotubes in selected human cell lines.” Science of the Total Environment. 408: 1812-1817. Xueheng Zhao, Xiaoke Hu, Huey-min Hwang. (2010) “A study of the toxicity of parathion and its major degradation products.”International Journal of Environmental Engineering Science. 1: 49-56.Xiaoke Hu, Peng Wang, Huey-min Hwang. (2009) “Oxidation of anthracene by immobilized laccase from Trametesversicolor.” Bioresource Technology. 100: 4963-4968.Xiaoke Hu, Sean Cook, Peng Wang, Huey-min Hwang. (2009) “In vitro eva luation of cytotoxicity of engineered metal oxide nanoparticles.” Science of the Total Environment. 407: 3070-3072.Winfred G. Aker, Xiaoke Hu, Peng Wang, Huey-min Hwang. (2008) “Comparing the relative toxicity of malathion and malaoxon in blue catfish Ictalurusfurcatus.” Environmental Toxicology. 23: 548-554.Peng Wang, Xiaoke Hu, Sean Cook, Maria Begonia, Ken S. Lee, Huey-Min Hwang. (2008) “Effect of culture conditions on the production of ligninolytic enzymes by white rot fungi Phanerochaetechrysosporium (ATCC 20696) and separation of its lignin peroxidase.” World J MicrobiolBiotechnol. 24:2205–2212.Yanhua Jiang, Xiaolu Jiang, Peng Wang, HaijinMou, Xiaoke Hu, Shuqing Liu. (2008) “The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinose B05.” Microbiological Research. 163: 424-430. Citation 15Peng Wang, Xiaolu Jiang, Yanhua Jiang, Xiaoke Hu, Huey-min Hwang. (2008) “Optimization of fermentation medium and conditions for mycelial growth and water-soluble exo-polysaccharids production by Isaria farinose B05.” Preparative Biochemistry and Biotechnology. 38: 294-307.Huey-min Hwang, Xiaoke Hu, Xueheng Zhao. (2007) “Enhanced bioremediation of polycyclic aromatic hydrocarbons by environmentally friendly techniques.” Journal of Environmental Science and Health. Part C, 25: 313-352.Xiaoke Hu, Yi Zhang, Xueheng Zhao, Huey-min Hwang. (2007) “Biodegradation of Benzo[a]pyrene with immobilized laccase: Genotoxicity of the products in HaCaT and A3 cells.” Environmental and Molecular Mutagenesis. 48: 106-113.Xiaoke Hu, Xueheng Zhao, Huey-min Hwang. (2007) “Comparative study of immobilized Trametesversicolorlaccase on nanoparticles and kaolinite.” Chemosphere. 66: 1618-1626.Peng Wang, Xiaolu Jiang, Yanhua Jiang, Xiaoke Hu, et al. (2007) “In vitroantioxidative activities of three marine oligosaccharides.” Natural Product Research. 21: 646-654.Xueheng Zhao, Yi Zhang, Xiaoke Hu, Huey-min Hwang. (2007) “Enhanced bio-mineralization by riboflavin photosensitization and its significance to detoxification of benzo[a]pyrene.” Bulletin of Environmental Contamination and Toxicology. 79: 319-322.Xiaoke Hu, Xiaolu Jiang. (2006) “Characterisations of seaweeds depolymerases and applications of their polysaccharide derivatives.” World Seaweed Resources. An authoritative reference system. Interactive multimedia DVD-ROM version.Xiaoke Hu, Xiaolu Jiang, Eric Aubree, Patrick Boulenguer, Alan T. Critchley. (2006) “Preparation and In vivo antitumor activity of κ-carrageenan oligosaccharides.” Pharmaceutical Biology. 44: 646-650.Xiaoke Hu, Xiaolu Jiang, Huey-min Hwang. (2006) “Purification and characterization of an alginate lyase from marine bacterium Vibrio sp. mutant strain 510-64.” Current Microbiology. 53: 135-140.Xueheng Zhao, Xiaoke Hu, Huey-min Hwang. (2006) “Effects of riboflavin on phototransformation of benzo[a]pyrene.” Chemosphere. 63: 1116-1123. Citation 9Xiaoke Hu, Xiaolu Jiang, Jun Gong et al. (2005) “Antibacterial activity of lyase-depolymerized products of alginate.” Journal of Applied Phycology. 17: 57-60.Yanhua Jiang, Xiaolu Jiang, Peng Wang, Xiaoke Hu. (2005) “In vitro antioxidant activities of water-soluble polysaccharides extracted from IsariaFarinosa B05.” Journal of Food Biochemistry. 29: 323. Hongxia Zhang, Xiaolu Jiang, HaijinMou, Xiaoke Hu. (2005) “Research progress on microbial pectinases.” Biotechnology 15: 92-95 (In Chinese with English abstract).Xiaoke Hu, Xiaolu Jiang, Huey-min Hwang et al. (2004) “Antitumour activities of alginate-derived oligosaccharides and their sulphated substitution derivatives.” European Journal of Phycology. 39: 67-71.Xiaoke Hu, Xiaolu Jiang. Huey-min Hwang et al. (2004) “Promotive effects of alginate-derived oligosaccharide on maize seed germination.” Journal of Applied Phycology. 16: 73-76.Shiliang Liu, Xiaolu Jiang, Xiaoke Hu, et al. (2004) “Effects of Temperature on Non-specific Immune parameters in Two Scallop Species: Argopectenirradians (Lamarck 1819) and Chlamysfarreri (Jones & Preston 1904).” Aquaculture Research. 35: 678-682.Xiaolu Jiang, Yan Liu, Xiaoke Hu, Huashi Guan. (2004) “Purification and substrate specificity of the alginate lyase from Vibiro sp. 510.” Journal of OceanUniversity of China. 34: 55-59 (in Chinese with English abstract).Xiaoke Hu, Xiaolu Jiang, Huashi Guan. (2003) “Isolation of protoplasts from Undariapinnatifidaby alginate lyase digestion.” Journal of OceanUniversity of Qingdao. 2: 58-61.