Mi, Yingqi1,2,3; Zhang, Jingjing1,2,3; Chen, Yuan1,2,3; Sun, Xueqi1,2,3; Tan, Wenqiang1,2
; Li, Qing1,2; Guo, Zhanyong1,2,3发表期刊CARBOHYDRATE POLYMERS
ISSN0144-8617
2020-12-01
卷号249页码:8
关键词Carboxymethyl chitosanHeterocyclic compoundsAntifungal activityAntioxidant activityCytotoxicity assay
DOI10.1016/j.carbpol.2020.116847
通讯作者Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要In this paper, several novel chitosan derivatives bearing benzenoid / heterocyclic moieties were synthesized via introducing aminobenzene and heterocyclic compounds onto carboxymethyl chitosan. The specific structures of chitosan derivatives were confirmed by FTIR, H-1 NMR, and elemental analysis. Meanwhile, the antioxidant efficiencies of chitosan derivatives were assayed in vitro. In particular, all chitosan derivatives showed significant improvement in superoxide-radical scavenging activity and DPPH radical scavenging activity. Their antifungal activities against two plant pathogenic fungi (Colletotrichum lagenarium and Phomopsis asparagi) were estimated in vitro by hyphal measurement, and all products exhibited excellent antifungal activity. Besides, the cytotoxicity of them was also measured by CCK-8 in vitro on L929 cells, and all samples showed low cytotoxicity. The good biocompatibility and enhanced biological activity of new synthetic chitosan derivatives might be obvious ad-vantages, while applied in wide range of applications as antifungal agents or antioxidants in food, medicine, cosmetics, and other fields.
资助机构National Key R&D Program of China; Key R&D Program of Shandong Province; Natural Science Foundation of Shandong Province of China
收录类别SCI
语种英语
关键词[WOS]IN-VITRO; NANOPARTICLES; BASES; ACID; NMR
研究领域[WOS]Chemistry; Polymer Science
WOS记录号WOS:000571541800001
引用统计被引频次：7[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/28400
专题海岸带生物学与生物资源利用重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者Guo, Zhanyong作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Mi, Yingqi,Zhang, Jingjing,Chen, Yuan,et al. New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities[J]. CARBOHYDRATE POLYMERS,2020,249:8.
APAMi, Yingqi.,Zhang, Jingjing.,Chen, Yuan.,Sun, Xueqi.,Tan, Wenqiang.,...&Guo, Zhanyong.(2020).New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities.CARBOHYDRATE POLYMERS,249,8.
MLAMi, Yingqi,et al."New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities".CARBOHYDRATE POLYMERS 249(2020):8.
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