其他题名ffect of wheat aleurone layer on serum lipid level and insulin resistance in rats with high fat diet
朱晓振
; 孟现尧; 贾晨晨; 超博; 范文勇; 李昕芮; 吴亮; 衣悦涛发表期刊食品科技
ISSN1005-9989
2019-08-20
卷号44期号:08页码:163-168
关键词小麦糊粉层高脂膳食血脂胰岛素抵抗大鼠
产权排序(1) 中国科学院烟台海岸带研究所; (2) 中国科学院大学; (3) 滨州医学院临床医学院; (4) 山东知食坊食品科技有限公司
作者部门海岸带生物学与生物资源保护实验室
英文摘要The effects of wheat aleurone layer on blood lipid level and insulin resistance in rats with highfat diet were studied. The rats were administered by gavage with aleurone layer for 5 successive weeks. Compared with the control group, the rats in the wheat aleurone layer group were significantly reduced in weight gain(P <0.05) and the food intake was also reduced. Serum levels of TC, TG and LDL-C were significantly decreased, while HDL-C significantly increased(P<0.05). Meanwhile, the blood lipid ratio TC/HDL-C, TG/HDL-C, LDL-C/HDL-C and AI levels were improved. Serum FBG, HOMA-IR(P<0.05), ISI, and HOMA-β index were significantly reduced while T-SOD levels increased significantly(P<0.05) by aleurone layer intervention, which could alleviate insulin resistance in rats with high-fat diet. The liver body ratio and liver fat accumulation with wheat aleurone layer intervene was significantly reduced. The results showed that aleurone layer can interfere with high-fat diet, play a role in reducing blood lipid, alleviating insulin resistance, improving liver fat accumulation, and reduce the occurrence of related diseases.
中文摘要以高脂膳食大鼠为研究对象,研究小麦糊粉层对大鼠血脂水平及胰岛素抵抗的影响。灌胃5周,结果表明小麦糊粉层可以明显减缓高脂膳食大鼠体质量增加(P <0.05)和食物摄入量。血清甘油三酯(TC)、总胆固醇(TG)和低密度脂蛋白(LDL-C)的水平显著降低,高密度脂蛋白(HDL-C)水平显著升高(P<0.05)、胰岛素敏感指数(ISI)和胰岛β细胞功能指数(HOMA-β)显著降低(P<0.05),高脂膳食大鼠胰岛素抵抗得到缓解。小麦糊粉层剂量组肝体比明显降低,肝脏脂肪堆积明显减少。研究结果表明,小麦糊粉层干预高脂膳食,可起到降低血脂、缓解胰岛素抵抗、改善肝脏脂肪堆积的作用。
文章类型期刊论文
资助机构中国科学院STS重点项目(KFJ-STS-ZDTP-023)
收录类别其他
语种中文
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25197
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.中国科学院烟台海岸带研究所;
2.中国科学院大学;
3.滨州医学院临床医学院;
4.山东知食坊食品科技有限公司
推荐引用方式
GB/T 7714朱晓振,孟现尧,贾晨晨,等. 小麦糊粉层对高脂膳食大鼠血脂水平及胰岛素抵抗的影响[J]. 食品科技,2019,44(08):163-168.
APA朱晓振.,孟现尧.,贾晨晨.,超博.,范文勇.,...&衣悦涛.(2019).小麦糊粉层对高脂膳食大鼠血脂水平及胰岛素抵抗的影响.食品科技,44(08),163-168.
MLA朱晓振,et al."小麦糊粉层对高脂膳食大鼠血脂水平及胰岛素抵抗的影响".食品科技 44.08(2019):163-168.
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