Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang
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发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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ISSN0141-8130
2020-06-01
卷号152页码:349-358
关键词STARCH DERIVATIVESLIGANDS SYNTHESISTHIOETHERANTIFUNGALCOMPLEXES
研究领域Biochemistry & Molecular Biology; Chemistry, Applied; Polymer Science
DOI10.1016/j.ijbiomac.2020.02.177
产权排序[Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者Guo, Zhanyong(zhanyongguo@hotmail.com)
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要In this study, a new class of chitosan derivatives possessing sulfonium salts was synthesized, and characterized by H-1 NMR, C-13 NMR, and elemental analyses. IR spectra, H-1 NMR and C-13 NMR of the structural units of these polymers validated the designed chitosan derivatives were successfully synthesized. In addition, the antioxidant potential of chitosan and chitosan derivatives was assessed in vitro, screened by 2,2-diphenyl-l-picrylhydrazyl (DPPH) free radical scavenging, hydroxyl radical scavenging, and superoxide radical scavenging, respectively. Results revealed that designed chitosan derivatives could effectively scavenge DPPH radical, hydroxyl radical, and superoxide radical with inhibition rate of more than 90% at 1.6 mg/mL, higher than chitosan. Moreover, in the cytotoxicity assay, no cytotoxicity was observed for the 1929 cells with chitosan and its derivatives at all the testing concentrations. These results indicated that the acetylated chitosan derivatives containing sulfonium salts may be a promising natural antioxidant for the pharmaceutics, food, cosmetics and agriculture management. (C) 2020 Elsevier B.V. All rights reserved.
文章类型Article
资助机构National Key Research and Development Program of China [2019YFD0900705]; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2019BD064, ZR2017BD015]; Youth Innovation Promotion Association CAS [2020219]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156]; Natural Science Foundation of Shandong Province Science and Technology Development Plan [2019GHY112010]
收录类别SCI
语种英语
关键词[WOS]STARCH DERIVATIVES; LIGANDS SYNTHESIS; THIOETHER; ANTIFUNGAL; COMPLEXES
研究领域[WOS]Biochemistry & Molecular Biology; Chemistry; Polymer Science
WOS记录号WOS:000530068000036
引用统计被引频次:4[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25022
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China;
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Sun, Xueqi,Zhang, Jingjing,Mi, Yingqi,et al. Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2020,152:349-358.
APASun, Xueqi.,Zhang, Jingjing.,Mi, Yingqi.,Chen, Yuan.,Tan, Wenqiang.,...&Guo, Zhanyong.(2020).Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,152,349-358.
MLASun, Xueqi,et al."Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 152(2020):349-358.
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