Wei, LJ; Tan, WQ
; Zhang, JJ; Mi, YQ; Dong, F; Li, Q; Guo, ZY发表期刊POLYMERS
2019-02
卷号11期号:2页码:371
关键词inulinSchiff baseantifungal
研究领域Polymer Science
DOI10.3390/polym11020371
产权排序[Wei, Lijie; Tan, Wenqiang; Zhang, Jingjing; Mi, Yingqi; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Wei, Lijie; Zhang, Jingjing; Mi, Yingqi; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要As a renewable, biocompatible, and biodegradable polysaccharide, inulin has a good solubility in water and some physiological functions. Chemical modification is one of the important methods to improve the bioactivity of inulin. In this paper, based on 6-amino-6-deoxy-3,4-acetyl inulin (3), three kinds of Schiff bases of inulin bearing pyridine rings were successfully designed and synthesized. Detailed structural characterization was carried out using FTIR, C-13 NMR, and H-1 NMR spectroscopy, and elemental analysis. Moreover, the antifungal activity of Schiff bases of inulin against three plant pathogenic fungi, including Botrytis cinerea, Fusarium oxysporum f.sp.niveum, and Phomopsis asparagi, were evaluated using in vitro hypha measurements. Inulin, as a natural polysaccharide, did not possess any antifungal activity at the tested concentration against the targeted fungi. Compared with inulin and the intermediate product 6-amino-6-deoxy-3,4-acetyl inulin (3), all the synthesized Schiff bases of inulin derivatives with >54.0% inhibitory index at 2.0 mg/mL exhibited enhanced antifungal activity. 3NS, with an inhibitory index of 77.0% exhibited good antifungal activity against Botrytis cinerea at 2.0 mg/mL. The synthesized Schiff bases of inulin bearing pyridine rings can be prepared for novel antifungal agents to expand the application of inulin.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156]; seed project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011]; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR 2017BD015]; Science and Technology Service Network Initiative of Chinese Academy of sciences [KFJ-STSZDTP-023]
收录类别SCI
语种英语
关键词[WOS]CHITOSAN DERIVATIVES; ANTIOXIDANT ACTIVITY; ANTIBACTERIAL
研究领域[WOS]Polymer Science
WOS记录号WOS:000460296000185
引用统计被引频次：8[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25004
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Wei, LJ,Tan, WQ,Zhang, JJ,et al. Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring[J]. POLYMERS,2019,11(2):371.
APAWei, LJ.,Tan, WQ.,Zhang, JJ.,Mi, YQ.,Dong, F.,...&Guo, ZY.(2019).Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring.POLYMERS,11(2),371.
MLAWei, LJ,et al."Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring".POLYMERS 11.2(2019):371.
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