Shi, ZZ; Miao, FP
; Fang, ST; Yin, XL; Ji, NY发表期刊FITOTERAPIA
ISSN0367-326X
2019-04
卷号134页码:372-377
关键词Trichoderma asperellumSesquiterpeneNorsesquiterpeneBisabolane
研究领域Chemistry, Medicinal; Pharmacology & Pharmacy
DOI10.1016/j.fitote.2019.03.010
产权排序[Shi, Zhen-Zhen; Miao, Feng-Ping; Fang, Sheng-Tao; Yin, Xiu-Li; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
通讯作者Ji, Nai-Yun(nyji@yic.ac.cn)
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要Eight new bisabolane derivatives, trichobisabolins A-H, along with two known ones, (3R,6R,7R)-1,10-bisaboladien-3-ol (9) and (3R,6R,7S)-1,10-bisaboladien-3,6-diol (10) were isolated from the culture of Trichoderma asperellum Y6-2, obtained from the surface of the marine red alga Chondrus ocellatus. Their structures and relative configurations were identified by interpretation of 1D/2D NMR and MS data. Compounds 1-8 were assayed for inhibiting the growth of some marine-derived organisms, including four marine phytoplankton species, one marine zooplankton species, and five pathogenic bacteria. All of them exhibited inhibition against the marine phytoplanktons with IC50 values ranging from 2.1-78 mu g/mL, compounds 4 and 8 showed weak lethality to the marine zooplankton, and none of them had inhibition against the five pathogenic bacteria.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31670355]; Natural Science Foundation for Distinguished Young Scholars of Shandong Province [JQ201712]; Key Cutting Edge Research Program of the Chinese Academy of Sciences [QYZDB-SSW-DQC013]; Youth Innovation Promotion Association of CAS [2013138]; Science and Technology Service Network Initiative of CAS [KFJ-STS-ZDTP-023]
收录类别SCI
语种英语
关键词[WOS]AGGREGATION PHEROMONE; SESQUITERPENOIDS; BUG
研究领域[WOS]Chemistry, Medicinal; Pharmacology & Pharmacy
WOS记录号WOS:000468710300045
引用统计被引频次：8[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24963
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Shi, ZZ,Miao, FP,Fang, ST,et al. Trichobisabolins A-H, eight new bisabolane derivatives from the marine alga-epiphytic fungus Trichoderma asperellum Y6-2[J]. FITOTERAPIA,2019,134:372-377.
APAShi, ZZ,Miao, FP,Fang, ST,Yin, XL,&Ji, NY.(2019).Trichobisabolins A-H, eight new bisabolane derivatives from the marine alga-epiphytic fungus Trichoderma asperellum Y6-2.FITOTERAPIA,134,372-377.
MLAShi, ZZ,et al."Trichobisabolins A-H, eight new bisabolane derivatives from the marine alga-epiphytic fungus Trichoderma asperellum Y6-2".FITOTERAPIA 134(2019):372-377.
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