Liu, Feng; Lu, Zhen; Wu, Huifeng
; Ji, Chenglong发表期刊ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
ISSN0147-6513
2019-03
卷号169页码:714-721
关键词CadmiumDose-dependentToxicological effectsHormesisPerinereis aibuhitensis
研究领域Environmental Sciences & Ecology; Toxicology
DOI10.1016/j.ecoenv.2018.11.098
产权排序[Liu, Feng] China Agr Univ, Yantai Res Inst, Ocean Coll, Yantai 264670, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China
作者部门海岸带环境过程实验室
英文摘要Cadmium is a known metal contaminant in the Bohai Sea. In this study, the dose-dependent responses induced by Cd were characterized in marine polychaete Perinereis aibuhitensis using the endpoints, including activities of enzymes, expression levels of stress-responsive genes and metabolic responses. Both enzyme activities and gene expression levels exhibited the hormetic effects induced by Cd in P. aibuhitensis, as shown by the typical U-shaped or inverted U-shaped response profiles. The highest concentration (1280 mu g/L) of Cd exposure induced obvious oxidative stresses. NMR-based metabolomics revealed that Cd induced both linear dose-dependent effects (69.13% of the total variation) and a relatively slight hormesis (5.54% of the total variation) in energy metabolism in P. aibuhitensis at metabolite level. In details, Cd exposures linearly reduced the consumption of amino acids and enhanced the consumption of glucose for energy supply, resulting in elevated contents of amino acids and depleted contents of glucose. Additionally, Cd treatments induced hormesis in the conversion of ATP hydrolysis to AMP. This work suggested that the hormetic effects should be considered in the ecological risk assessment for the environmental pollutants.
文章类型Article
资助机构National Natural Science Foundation of China [41676114]; National Key Basic Research Program of China [2015CB453303]; Qingdao National Laboratory for Marine Science and Technology [QNLM201701]; Youth Innovation Promotion Association CAS [2015169]
收录类别SCI
语种英语
关键词[WOS]SHRIMP CRANGON-AFFINIS; METABOLIC-RESPONSES; METAL POLLUTION; HORMESIS; TOXICITY
研究领域[WOS]Environmental Sciences; Toxicology
WOS记录号WOS:000456226600085
引用统计被引频次：8[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24641
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.China Agr Univ, Yantai Res Inst, Ocean Coll, Yantai 264670, Peoples R China;
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China;
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
4.YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Liu, Feng,Lu, Zhen,Wu, Huifeng,et al. Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2019,169:714-721.
APALiu, Feng,Lu, Zhen,Wu, Huifeng,&Ji, Chenglong.(2019).Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,169,714-721.
MLALiu, Feng,et al."Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 169(2019):714-721.
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