Zhang, Jingjing; Tan, Wenqiang
; Mi, Yingqi; Luan, Fang; Wei, Lijie; Li, Qing; Dong, Fang; Guo, Zhanyong发表期刊STARCH-STARKE
ISSN0038-9056
2019-01
卷号71期号:1-2页码:1800058-
关键词antifungal activityinulin derivativesstructure characteristicssynthesisurea groups
研究领域Food Science & Technology
DOI10.1002/star.201800058
产权排序[Zhang, Jingjing; Tan, Wenqiang; Mi, Yingqi; Luan, Fang; Wei, Lijie; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Zhang, Jingjing; Tan, Wenqiang; Mi, Yingqi; Luan, Fang; Wei, Lijie; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要The toxicity concerns associated with chemical fungicides currently on the market have resulted in an increased demand for alternative ecofriendly fungicides. As a biodegradable and biocompatible dietary fiber, inulin shows potential as such a compound, given its lack of toxicity. In the current study, seven novel inulin derivatives with promising antifungal activity (BUCAIL, 2CBUCAIL, 3CBUCAIL, 4CBUCAIL, 3,4CBUCAIL, 2FBUCAIL, and 2BBUCAIL) are synthesized via condensation reactions of chloroacetyl inulin (CAIL) with urea groups bearing 4-amino-pyridine. Their structures are confirmed using FT-IR, H-1 NMR, C-13 NMR, and elemental analysis. Their antifungal activity against three kinds of phytopathogen (Fusarium oxysporum f. sp. niveum, Phomopsis asparagus, and Fusarium oxysporum f. sp. cucumebrium Owen) is evaluated using the mycelial growth rate in vitro at concentrations of 0.10, 0.25, 0.50, 0.75, and 1.0 mg mL(-1). Results reveal that all seven inulin derivatives show improved antifungal properties compared with unmodified inulin, and two obvious inhibition rules are found: 3,4CBUCAIL > 4CBUCAIL > 3CBUCAIL > 2CBUCAIL > BUCAIL > CAIL > inulin and 2FBUCAIL > 2CBUCAIL > 2BBUCAIL > BUCAIL > CAIL > inulin. Thus, the introduction of urea groups into inulin derivatives could be key to increasing the antifungal activity of such compounds.
文章类型Article
资助机构National Natural Science Foundation of China [41576156]; Shandong Province Science and Technology Development Plan [2015GSF121045]; Yantai Science and Technology Development Plan [2015ZH078]; Technology Research Funds Projects of Ocean [2015418022-3]
收录类别SCI
语种英语
关键词[WOS]ANTIBACTERIAL ACTIVITY; ANTIOXIDANT; COMPLEXES; ESTERS
研究领域[WOS]Food Science & Technology
WOS记录号WOS:000454708500012
引用统计被引频次：3[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24608
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Zhang, Jingjing,Tan, Wenqiang,Mi, Yingqi,et al. Synthesis and Characterization of Inulin Derivatives Bearing Urea Groups with Promising Antifungal Activity[J]. STARCH-STARKE,2019,71(1-2):1800058-.
APAZhang, Jingjing.,Tan, Wenqiang.,Mi, Yingqi.,Luan, Fang.,Wei, Lijie.,...&Guo, Zhanyong.(2019).Synthesis and Characterization of Inulin Derivatives Bearing Urea Groups with Promising Antifungal Activity.STARCH-STARKE,71(1-2),1800058-.
MLAZhang, Jingjing,et al."Synthesis and Characterization of Inulin Derivatives Bearing Urea Groups with Promising Antifungal Activity".STARCH-STARKE 71.1-2(2019):1800058-.
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