Tan, Wenqiang
; Zhang, Jingjing; Mi, Yingqi; Dong, Fang; Li, Qing; Guo, Zhanyong发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN0141-8130
2018-12
卷号120期号:A页码:318-324
关键词ChitosanChemical modificationQuaternary ammonium group1,2,3-TriazoleAntifungal activityAntioxidant property
研究领域Biochemistry & Molecular Biology; Chemistry; Polymer Science
DOI10.1016/j.ijbiomac.2018.08.111
产权排序[Tan, Wenqiang; Zhang, Jingjing; Mi, Yingqi; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Tan, Wenqiang; Zhang, Jingjing; Mi, Yingqi; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要In this work, quatenary ammonium group was introduced into chitosan backbone by cuprous-catalyzed azide-alkyne cycloaddition (CuAAC) to synthesize the cationic chitosan derivative bearing 1,2,3-triazole. The products were identified structurally by FTIR, H-1 NMR spectroscopy. XRD, and elemental analysis. The water solubility of chitosan derivatives at different pH values was determined by a turbidity measurement. The antifungal properties of cationic chitosan derivatives against Botryis cinerea, Phomopsis asparagi, Fusarium oxysporum f.sp.niveum, and Fusarium oxysporum f.sp.cucumerium were evaluated using the radial growth assay. Besides, the antioxidant activities of them were also tested by superoxide-radical scavenging and reducing power assays. Compared to chitosan, cationic chitosan derivative bearing 1,2,3-triazole showed the good water solubility especially at alkaline condition, excellent antifungal action with over 70% inhibitory indices against tested fungi at 1.0 mg/ml, and enhanced antioxidant activity with complete scavenging efficiency against superoxide-radical at 1.6 mg/mL because of the introduction of 1,2,3-triazole and quaternary ammonium moieties. These excellent biological properties present a promising prospect for this chitosan derivative in antifungal and antioxidant biomaterials. (C) 2018 Published by Elsevier B.V.
文章类型Article
资助机构National Natural Science Foundation of China [41576156]; Natural Science Foundation of Shandong Province of China [ZR2017BD015]; Science and Technology Service Network Initiative of Chinese Academy of sciences [KFJ-STS-ZDTP-023]; Public Science and Technology Research Funds Projects of Ocean [201505022-3]
收录类别SCI
语种英语
关键词[WOS]QUATERNIZED CHITOSAN; ANTIBACTERIAL ACTIVITY; STARCH DERIVATIVES; AMMONIUM; CHEMISTRY
研究领域[WOS]Biochemistry & Molecular Biology; Chemistry, Applied; Polymer Science
WOS记录号WOS:000452587500038
引用统计被引频次：17[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24592
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Tan, Wenqiang,Zhang, Jingjing,Mi, Yingqi,et al. Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,120(A):318-324.
APATan, Wenqiang,Zhang, Jingjing,Mi, Yingqi,Dong, Fang,Li, Qing,&Guo, Zhanyong.(2018).Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,120(A),318-324.
MLATan, Wenqiang,et al."Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 120.A(2018):318-324.
PDF全文下载地址:
点我下载PDF
