Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang
; Chen, Yuan; Wang, Ping; Dong, Fang; Li, Qing; Guo, Zhanyong发表期刊STARCH-STARKE
ISSN0038-9056
2018-11
卷号70期号:11-12页码:1800026
关键词antifungal activityN-diquaternized chitinN-quaternized chitinquaternary ammonium salt
研究领域Food Science & Technology
DOI10.1002/star.201800026
产权排序[Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Wang, Ping] Binzhou Med Univ Hosp, Dept Infect Dis, Binzhou 256603, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要To improve the bioactivity of chitin (CT), novel N-quaternized (QCT), and N-diquaternized (DQCT) CT derivatives are synthesized through a series of reactions from CT. The derivatives are characterized using elemental analysis, FTIR, and C-13 NMR. In addition, the inhibitory effects of the compounds against three fungi (B. cinerea, F. oxysporum, and P. asparagi) are tested. The inhibitory indices of CT, QCT, and DQCT are 12-15%, 63-73%, and 74-89%, respectively, at 1.0 mg mL(-1). The antifungal activities are in the order of DQCT > QCT > CT, which correlated with the number of quaternized groups. Based on these results, it is concluded that the antifungal activity of CT is improved by the introduction of quaternized groups on CT backbone.
文章类型Article
资助机构National Natural Science Foundation of China [41576156]; Natural Science Foundation of Shandong Province of China [ZR2017BD015]; Yantai Science and Technology Development Plan [2015ZH078, 2015418022-3]; Technology Research Funds Projects of Ocean [2015418022-3]
收录类别SCI
语种英语
关键词[WOS]FACILE CHEMICAL-MODIFICATIONS; CHITOSAN DERIVATIVES; ANTIBACTERIAL ACTIVITY; ANTIOXIDANT ACTIVITIES; ANTIMICROBIAL ACTIVITY; BETA-CHITIN; IN-VITRO; EXTRACTION; PRECURSORS
研究领域[WOS]Food Science & Technology
WOS记录号WOS:000449763300030
引用统计被引频次：1[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24564
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
3.Binzhou Med Univ Hosp, Dept Infect Dis, Binzhou 256603, Peoples R China
推荐引用方式
GB/T 7714Luan, Fang,Wei, Lijie,Zhang, Jingjing,et al. Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives[J]. STARCH-STARKE,2018,70(11-12):1800026.
APALuan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives.STARCH-STARKE,70(11-12),1800026.
MLALuan, Fang,et al."Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives".STARCH-STARKE 70.11-12(2018):1800026.
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