Zhang, Jingjing; Tan, Wenqiang
; Luan, Fang; Yin, Xiuli; Dong, Fang; Li, Qing; Guo, Zhanyong发表期刊POLYMERS
ISSN2073-4360
2018-05
卷号10期号:5页码:530
关键词quaternary ammonium salts of chitosanhalogenated acetatecharacterizationantifungal activityantibacterial activity
研究领域Polymer Science
DOI10.3390/polym10050530
产权排序[Zhang, Jingjing; Tan, Wenqiang; Luan, Fang; Yin, Xiuli; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Zhang, Jingjing; Tan, Wenqiang; Luan, Fang; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要In this paper, quaternary ammonium salts of chitosan bearing halogenated acetate, including N,N,N-trimethyl chitosan chloroacetate (TMCSC), N,N,N-trimethyl chitosan dichloroacetate (TMCSDC), N,N,N-trimethyl chitosan trichloroacetate (TMCSTC), and N,N,N-trimethyl chitosan trifluoroacetate (TMCSTF), were prepared via N,N,N-trimethyl chitosan iodide (TMCSI). The obtained chitosan derivatives were characterized by FT-IR, H-1 NMR spectra, C-13 NMR spectra, and elemental analysis. Their antifungal property against Fusarium oxysporum f. sp. cucumebrium Owen (F. oxysporum f. sp. cucumebrium Owen), Botrytis cinerea (B. cinerea), and Phomopsis asparagi (P. asparagi) were evaluated by hyphal measurement method at concentrations ranging from 0.08 mg/mL to 0.8 mg/mL. Meanwhile, two common bacteria, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), were selected as the model Gram-negative and Gram-positive bacteria to evaluate the antibacterial property of the chitosan derivatives by agar well diffusion method. The results showed that TMCSC, TMCSDC, TMCSTC, and TMCSTF had better antifungal and antibacterial activities than chitosan and TMCSI. In particular, a rule showed that the inhibitory activity decreased in the order: TMCSTF > TMCSTC > TMCSDC > TMCSC > TMCSI > chitosan, which was consistent with the electron-withdrawing property of different halogenated acetate. Apparently, the quaternary ammonium salts of chitosan with stronger electron withdrawing ability possessed relatively greater antifungal and antibacterial activities. This experiment provides a potentially feasible method for the further utilization of chitosan in fields of antifungal and antibacterial biomaterials.
文章类型Article
资助机构National Natural Science Foundation of China [41576156]; Natural Science Foundation of Shandong Province of China [ZR2017BD015]; Yantai Science and Technology Development Plan [2015ZH078]; Technology Research Funds Projects of Ocean [2015418022-3]
收录类别SCI
语种英语
关键词[WOS]ANTIMICROBIAL ACTIVITY; DERIVATIVES; PROPERTY; NANOPARTICLES; CONJUGATION; HYDROGELS
研究领域[WOS]Polymer Science
WOS记录号WOS:000435199300068
引用统计被引频次：9[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24470
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Zhang, Jingjing,Tan, Wenqiang,Luan, Fang,et al. Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities[J]. POLYMERS,2018,10(5):530.
APAZhang, Jingjing.,Tan, Wenqiang.,Luan, Fang.,Yin, Xiuli.,Dong, Fang.,...&Guo, Zhanyong.(2018).Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities.POLYMERS,10(5),530.
MLAZhang, Jingjing,et al."Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities".POLYMERS 10.5(2018):530.
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