Bi, Liyan; Wang, Yunqing


发表期刊ACS APPLIED MATERIALS & INTERFACES

ISSN1944-8244
2018-05-09
卷号10期号:18页码:15381-15387
关键词gold nanorod array4-MPySERSRSDpH sensorCS7BL/6 mouse blood
研究领域Science & Technology - Other Topics; Materials Science
DOI10.1021/acsami.7b19347
产权排序[Bi, Liyan; Yang, Ying; Zheng, Qingyin] Binzhou Med Univ, Transformat Otol & Neurosci Ctr, Coll Special Educ, Yantai 264003, Peoples R China; [Li, Yuling] Binzhou Med Univ, Dept Pathophysiol, Yantai 264003, Peoples R China; [Mo, Shanshan] Binzhou Med Univ, Dept Pharm, Yantai 264003, Peoples R China; [Wang, Yunqing; Chen, Lingxin] Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
作者部门海岸带环境过程实验室
英文摘要Conventional research on surface-enhanced Raman scattering (SERS)-based pH sensors often depends on nanoparticle aggregation, whereas the variability in nanoparticle aggregation gives rise to poor repeatability in the SERS signal. Herein, we fabricated a gold nanorod array platform via an efficient evaporative self-assembly method. The platform exhibits great SERS sensitivity with an enhancement factor of 5.6 X 10(7) and maintains excellent recyclability and reproducibility with relative standard deviation (RSD) values of less than 8%. On the basis of the platform, we developed a highly sensitive bovine serum albumin (BSA)-coated 4-mercaptopyridine (4-MPy)-linked (BMP) SERS-based pH sensor to report pH ranging from pH 3.0 to pH 8.0. The intensity ratio variation of 1004 and 1096 cm(-1) in 4-MPy showed excellent pH sensitivity, which decreased as the surrounding pH increased. Furthermore, this BMP SERS-based pH sensor was employed to measure the pH value in C57BL/6 mouse blood. We have demonstrated that the pH sensor has great advantages such as good stability, reliability, and accuracy, which could be extended for the design of point-of-care devices.
文章类型Article
资助机构National Natural Science Foundation of China [21605005, 81530030, 81573393, 21575159, 51401031
收录类别SCI
语种英语
关键词[WOS]ENHANCED RAMAN-SCATTERING; FEMTOMOLAR DETECTION; NANOPARTICLES; SPECTROSCOPY; FLUORESCENCE; DECORATION; MONOLAYER; SUBSTRATE; FILMS; SHAPE
研究领域[WOS]Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
WOS记录号WOS:000432205800007
引用统计被引频次:46[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24463
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Binzhou Med Univ, Transformat Otol & Neurosci Ctr, Coll Special Educ, Yantai 264003, Peoples R China;
2.Binzhou Med Univ, Dept Pathophysiol, Yantai 264003, Peoples R China;
3.Binzhou Med Univ, Dept Pharm, Yantai 264003, Peoples R China;
4.Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Bi, Liyan,Wang, Yunqing,Yang, Ying,et al. Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(18):15381-15387.
APABi, Liyan.,Wang, Yunqing.,Yang, Ying.,Li, Yuling.,Mo, Shanshan.,...&Chen, Lingxin.(2018).Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform.ACS APPLIED MATERIALS & INTERFACES,10(18),15381-15387.
MLABi, Liyan,et al."Highly Sensitive and Reproducible SERS Sensor for Biological pH Detection Based on a Uniform Gold Nanorod Array Platform".ACS APPLIED MATERIALS & INTERFACES 10.18(2018):15381-15387.
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