Mei, Rongchao1,2; Wang, Yunqing1,2
; Liu, Wanhui2; Chen, Lingxin1,3发表期刊ACS APPLIED MATERIALS & INTERFACES
ISSN1944-8244
2018-07-18
卷号10期号:28页码:23605-23616
关键词gold nanoparticlecore-satellite nanoparticlein situ growthlipid bilayersurface-enhanced Raman scattering tagsbioimaging
研究领域Science & Technology - Other Topics; Materials Science
DOI10.1021/acsami.8b06253
产权排序[Mei, Rongchao; Wang, Yunqing; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Mei, Rongchao; Wang, Yunqing; Liu, Wanhui] Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China; [Chen, Lingxin] Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China
通讯作者Wang, Yunqing(yqwang@yic.ac.cn); Chen, Lingxin(lxchen@yic.ac.cn)
作者部门海岸带环境过程实验室
英文摘要Herein, we presented waxberry-like core satellite (C-S) nanoparticles (NPs) prepared by an in situ growth of satellite gold NPs on spherical phospholipid bilayer-coated gold cores. The fluidic lipid bilayer cross-linker was reported for the first time, which imparted several novel morphological and optical properties to the C-S NPs. First, it regulated the anisotropic growth of the satellite NPs into vertically oriented nanorods on the core NP surface. Thus, an interesting waxberry-like nanostructure could be obtained, which was different from the conventional raspberry-like C-S structures decorated with spherical satellite NPs. Second, the satellite NPs were "soft-landed" on the lipid bilayer and could move on the core NP surface under certain conditions. The movement induced tunable plasmonic features in the C-S NPs. Furthermore, the fluidic lipid bilayer was capable of not only holding an abundance of reporter molecules but also delivering them to the hotspots at the junctions between the core and satellite NPs, which made the C-S NPs an excellent candidate for preparing ultrasensitive surface-enhanced Raman scattering (SERS) tags. The bioimaging capabilities of the C-S NP-based SERS tags were successfully demonstrated in living cells and mice. The developed SERS tags hold great potential for bioanalysis and medical diagnostics.
文章类型Article
资助机构National Natural Science Foundation of China; Science and Technology Development Plan of Shandong Province of China; Youth Innovation Promotion Association CAS; Defense Science and Technology Innovation Fund of the Chinese Academy of Sciences; Instrument Developing Project of the Chinese Academy of Sciences
收录类别SCI
语种英语
关键词[WOS]GOLD NANOPARTICLES; SERS TAGS; PLASMONIC SUPERSTRUCTURES; PHOSPHOLIPID-BILAYERS; PHOTOTHERMAL THERAPY; OPTICAL-PROPERTIES; SPECTROSCOPY; ASSEMBLIES; LIPOSOMES; CANCER
研究领域[WOS]Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
WOS记录号WOS:000439528400021
引用统计被引频次：24[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24435
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
2.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China;
3.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China
推荐引用方式
GB/T 7714Mei, Rongchao,Wang, Yunqing,Liu, Wanhui,et al. Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(28):23605-23616.
APAMei, Rongchao,Wang, Yunqing,Liu, Wanhui,&Chen, Lingxin.(2018).Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging.ACS APPLIED MATERIALS & INTERFACES,10(28),23605-23616.
MLAMei, Rongchao,et al."Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging".ACS APPLIED MATERIALS & INTERFACES 10.28(2018):23605-23616.
PDF全文下载地址:
点我下载PDF
