Yang, Qian; Li, Jinhua
; Wang, Xiaoyan; Peng, Hailong; Xiong, Hua; Chen, Lingxin发表期刊BIOSENSORS & BIOELECTRONICS
ISSN0956-5663
2018-07-30
卷号112页码:54-71
关键词Molecular imprintingSensorFluorescent detectionConstruction strategyMicrodevice
研究领域Biophysics; Biotechnology & Applied Microbiology; Chemistry; Electrochemistry; Science & Technology - Other Topics
DOI10.1016/j.bios.2018.04.028
产权排序[Yang, Qian; Peng, Hailong; Xiong, Hua] Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China; [Yang, Qian; Li, Jinhua; Wang, Xiaoyan; Chen, Lingxin] Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Yang, Qian; Li, Jinhua; Wang, Xiaoyan; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, Yantai 264003, Peoples R China; [Wang, Xiaoyan] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
作者部门海岸带环境过程实验室
英文摘要One pressing concern today is to construct sensors that can withstand various disturbances for highly selective and sensitive detecting trace analytes in complicated samples. Molecularly imprinted polymers (MIPs) with tailor-made binding sites are preferred to be recognition elements in sensors for effective targets detection, and fluorescence measurement assists in highly sensitive detection and user-friendly control. Accordingly, molecular imprinting-based fluorescence sensors (MI-FL sensors) have attracted great research interest in many fields such as chemical and biological analysis. Herein, we comprehensively review the recent advances in MI-FL sensors construction and applications, giving insights on sensing principles and signal transduction mechanisms, focusing on general construction strategies for intrinsically fluorescent or nonfluorescent analytes and improvement strategies in sensing performance, particularly in sensitivity. Construction strategies are well overviewed, mainly including the traditional indirect methods of competitive binding against pre-bound fluorescent indicators, employment of fluorescent functional monomers and embedding of fluorescence substances, and novel rational designs of hierarchical architecture (core-shell/hollow and mesoporous structures), post-imprinting modification, and ratiometric fluorescence detection. Furthermore, MI-FL sensor based microdevices are discussed, involving micromotors, test strips and microfluidics, which are more portable for rapid point-of-care detection and in-field diagnosing. Finally, the current challenges and future perspectives of MI-FL sensors are proposed.
文章类型Article
资助机构National Natural Science Foundation of China [21667018, 21477160, 31660482, 41776110, 21575159]; Natural Science Foundation of Shandong Province of China [ZR2016BL25]
收录类别SCI
语种英语
关键词[WOS]GRAPHENE QUANTUM DOTS; METAL-ORGANIC FRAMEWORKS; CORE-SHELL PARTICLES; ONE-POT SYNTHESIS; UP-CONVERSION; RATIOMETRIC FLUORESCENCE; SENSITIVE DETECTION; SELECTIVE DETECTION; BISPHENOL-A; POLYMER NANOPARTICLES
研究领域[WOS]Biophysics; Biotechnology & Applied Microbiology; Chemistry, Analytical; Electrochemistry; Nanoscience & Nanotechnology
WOS记录号WOS:000433648000008
引用统计被引频次：146[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24433
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China;
2.Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, Yantai 264003, Peoples R China;
4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Yang, Qian,Li, Jinhua,Wang, Xiaoyan,et al. Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis[J]. BIOSENSORS & BIOELECTRONICS,2018,112:54-71.
APAYang, Qian,Li, Jinhua,Wang, Xiaoyan,Peng, Hailong,Xiong, Hua,&Chen, Lingxin.(2018).Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis.BIOSENSORS & BIOELECTRONICS,112,54-71.
MLAYang, Qian,et al."Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis".BIOSENSORS & BIOELECTRONICS 112(2018):54-71.
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