其他题名Bioaccumulation and biotransformation of inorganic arsenic in Ruditapes philippinarum
陈丽竹; 王丹; 曹瑞文; 王清
; 赵建民; 祝艳霞; 吴惠丰发表期刊海洋通报
ISSN1001-6392
2017-06-15
卷号36期号:3页码:326-332
关键词Ruditapes philippinarumarsenicbioaccumulationbiotransformation菲律宾蛤仔砷富集甲基转化
DOIDoi:10.11840/j.issn.1001-6392.2017.03.011
产权排序(1) 中国科学院烟台海岸带研究所中国科学院海岸带环境过程与生态修复重点实验室; (2) 中国科学院大学; (3) 宁波大学
作者部门海岸带环境过程实验室
英文摘要Arsenic (As) is a ubiquitous toxic metalloid, and its toxicity depends greatly on its chemical speciation. Marine mollusks are apt to bioaccumulation of high arsenic contents because of their living habits. In this study, the bioaccumulation and biotransformation of the clam Ruditapes philippinarum were investigated after waterborne exposure to arsenite (As (Ⅲ)) or arsenate (As (Ⅴ)) for 14 days. The results showed that arsenic uptake increased with increasing arsenic concentration in the seawater, while gills of R. philippinarum showed the limited ability to bioaccumulate inorganic arsenic from seawater, with no significant difference compared with control group following waterbone 10 mug/L As (Ⅲ) and As (Ⅴ) exposure for 14 days. The bioavailability of As (Ⅲ) was slightly higher than that of As (Ⅴ) to R. philippinarum, and arsenic was easier to be accumulated in digestive glands. The results demonstrated the As biotransformation in the clams included As (Ⅴ) reduction, As (Ⅲ) oxidation, and methylation. Arsenobetaine (AsB) and dimethylarsinic acid (DMA) was the major arsenic speciation in all treatments, while monomethylarsonic acid (MMA) contents decreased significantly after exposure, indicating that MMA can be quickly metabolized or converted into other arsenic speciation in the rate-limiting conversion reaction of inorganic arsenic. Inorganic arsenic in gills was mainly converted to DMA, but AsB in digestive glands, indicating the different transformation efficiency in different tissues. In summary, the results provided an important basis for elucidating the arsenic bioaccumulation and biotransformation mechanism in R. philippinarum and provided theoretical basis for shellfish breeding and food safety.
中文摘要砷是具有类金属特性的污染物,不同赋存形态的砷毒性差异极大,海洋贝类由于其生活习性易于富集高浓度的砷,本研究以菲律宾蛤仔(Ruditapes philippinarum)为对象,探讨其在亚砷酸盐(arsenite,AsⅢ)和砷酸盐(arsenate,AsⅤ)暴露14天后的生物富集和转化规律。结果表明,菲律宾蛤仔对砷的积累量随海水中无机砷浓度的升高而逐渐增加。但菲律宾蛤仔鳃组织对砷的生物利用度很低,10滋g/L暴露组菲律宾蛤仔鳃组织对砷的积累量与对照组相比无显著差异。菲律宾蛤仔对三价砷的生物利用度高于五价砷,且砷更易于在菲律宾蛤仔肝胰腺中积累。菲律宾蛤仔组织中无机砷转化过程主要包括As (Ⅲ)氧化,As (Ⅴ)还原和甲基转化。在对照组和各暴露组有机砷砷甜菜碱(AsB)和二甲基胂酸(dimethylarsinic acid,DMA)是主要赋存形态,一甲基胂酸(monomethylarsonic acid,MMA)在100滋g/LAs (Ⅴ)暴露处理后含量显著下降,表明在无机砷的限速转化反应中MMA可以较快地代谢或转化为其他赋存形态。无机砷在菲律宾蛤仔鳃组织中主要转化为DMA,肝胰腺中主要转化为AsB。以上研究结果为阐明菲律宾蛤仔的生物富集和转化机制提供了重要依据,同时也可为贝类安全养殖和食用提供一定理论依据。
文章类型Article
收录类别CSCD
语种中文
关键词[WOS]Environmental Sciences & Ecology
研究领域[WOS]Environmental Sciences & Ecology; 环境科学与生态学
CSCD记录号CSCD:6010872
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24266
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
作者单位1.中国科学院烟台海岸带研究所中国科学院海岸带环境过程与生态修复重点实验室;
2.中国科学院大学;
3.宁波大学
推荐引用方式
GB/T 7714陈丽竹,王丹,曹瑞文,等. 菲律宾蛤仔对三价和五价无机砷的富集转化规律[J]. 海洋通报,2017,36(3):326-332.
APA陈丽竹.,王丹.,曹瑞文.,王清.,赵建民.,...&吴惠丰.(2017).菲律宾蛤仔对三价和五价无机砷的富集转化规律.海洋通报,36(3),326-332.
MLA陈丽竹,et al."菲律宾蛤仔对三价和五价无机砷的富集转化规律".海洋通报 36.3(2017):326-332.
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