070300|化学专业硕士研究生指导教师
姓名 杨小凤 性别 女
民族 汉 出生年月 ?1977-03-07
学历|学位 博士研究生|工学博士 专业技术职务 副教授
行政职务 教师
联系电话 ** 移动电话 **
邮箱 chm_yangxf@ujn.edu.cn
通讯地址|邮编 山东省济南市南辛庄西路336号济南大学化学化工学院/250022|
招生方向(领域) 化学
研究领域、学习工作经历、学术兼职等情况

杨小凤，济南大学化学化工学院副教授。2000年毕业于山东建材学院，2005年获济南大学硕士学位，2009年获日本琦玉大学工学博士学位，2015年于北京生命科学研究所访学，2016年于山东大学开展博士后工作。


代表性科研成果及奖励：
（包括项目、鉴定、论文、专著、专利等) 目前从事的科研工作：以有机合成为主要研究手段，致力于多功能荧光探针的设计合成、细胞及活体成像等方面的研究。
主持科研项目：
1、国家自然科学基金青年项目，**，以NGR为智能载体的APN/CD13靶向近红外荧光探针的研究，2018/01-2020/12。
2、第62批中国博士后科学基金面上资助一等资助，2017M620288，智能型肿瘤组织靶向性近红外荧光探针的研究，2017/12-2019/12。
3、山东省自然科学基金（高校联合专项），ZR2015BL010，基于荧光共振能量转移机制的近红外比率型荧光探针的设计及生物成像应用，2015/08-2017/08。
发表的研究论文：
(1) Xiaofeng Yang*, Xiaojun Qin, Yexin Li, Mei Yan, Yu Cui, Guoxin Sun, TBET-based ratiometric fluorescent probe for Hg²⁺ in aqueous media and intracellular colorimetric imaging in live Hela cells. Biosensors and Bioelectronics 2018, 121, 62–71.
(2) Yan Zhang, Yexin Li, Xiaofeng Yang*, Yiming Ding, Zongshi Zhao, Xiaolei Liu, Zhen Yang, Yu Cui, A single-state fluorescent with bright white-light emission in the solid station and aggregation-induced emission enhancement compound for Pd0 detection. Talanta, 2018,179, 177-185.
(3) Xiaofeng Yang*, Yexin Li, Yiming Ding, Zongshi Zhao, Yan Zhang, Xiaolei Liu,Zhuangcai Fu, Yu Cui, Guoxin Sun, Guangyou Zhang, Mei Yan, Ratiometric & reversible fluorescent sensing of NaCN by an effectiveprobe based on phenanthro[9,10-d]imidazole platform, Sensors and Actuators B: Chemical, 2017, 253, 478–487.
(4) Xiaolei Liu, Jixun Han, Yan Zhang, Xiaofeng Yang*, Yu Cui, Guoxin Sun, A novel pH probe based on ratiometric fluorescent properties of dicyanomethylene-4H-chromene platform, Talanta, 2017,174, 59–63.
(5) Xiaofeng Yang*, Yexin Li, Zongshi Zhao,Yiming Ding, Yan Zhang, Xiaolei Liu, Yu Cui, Guoxin Sun, Guangyou Zhang and Mei Yan, Highly selective ratiometric fluorescent probe based on diketopyrrolopyrrole for Au³⁺: an experimental and theoretical study, New J. Chem., 2017, 41, 5055-5060.
(6) Xiaofeng Yang*, Xiaolei Liu, Yexin Li, Fan Wu, Jiaxin Mao, Yuan Yuan, Yu Cui*, Guoxin Sun, Guangyou Zhang, A differentially selective probe based on diketopyrrolopyrrole with fluorescence turn-on response to Fe³⁺, and dual-mode turn-on and ratiometric response to Au³⁺, and its application in living cell imaging, Biosensors and Bioelectronics, 2016, 80, 288-293.
(7) Xiaofeng Yang*, Yan Zhang, Yexin Li, Xiaolei Liu, Jiaxin Mao, Yuan Yuan, Yu Cui, Guoxin Sun, Guangyou Zhang , A diketopyrrolopyrrole-based fluorescence turn-on probe for the detection of Pb²⁺ in aqueous solution and living cells, RSC Adv., 2016, 6, 52004-52008.
(8) Xiaofeng Yang, Lijun Xie, Rui Ning, Xiaoqian Gong, Zheng Liu, Yexin Li, Luyi Zheng, Gege Zhang, Bin Gao, Yu Cui*, Guoxin Sun*, Guangyou Zhang, A diketopyrrolopyrrole-based near-infrared sensor for selectiverecognition of fluoride ions, Sensors and Actuators B: Chemical, 2015, 210, 784-794.
(9) Xiaofeng Yang*, Luyi Zheng, Lijun Xie, Zheng Liu, Yexin Li, Rui Ning, Gege Zhang, Xiaoqian Gong, Bin Gao, Chunxiang Liu, Yu Cui, Guoxin Sun, Guangyou Zhang, Colorimetric and On–Off fluorescent chemosensor for fluoride ionbased on diketopyrrolopyrrole, Sensors and Actuators B: Chemical, 2015, 207, 9-24.
(10) Xiaofeng Yang, Gege Zhang, Yexin Li, Zheng Liu, Xiaoqian Gong, Bin Gao, Guangyou Zhang, Yu Cui, Guoxin Sun, Colorimetric and fluorogenic signalling of fluoride ions by diketopyrrolopyrrole-based chemosensor, RSC Adv., 2015, 5, 22455-22462.
(11) Xiaofeng Yang, Xiaoqian Gong, Yexin Li, Zheng Liu, Bin Gao, Gege Zhang, Yu Cui, Guoxin Sun, Guangyou Zhang, Diketopyrrolopyrrole-based chemosensors for selective recognition of fluoride ions, Tetrahedron, 2015, 71, 5069-5077.
(12) Xiaofeng Yang*, Yu Cui, Yexin Li, Luyi Zheng, Lijun Xie, Rui Ning, Zheng Liu, Junling Lu, Gege Zhang, Chunxiang Liu, Guangyou Zhang, A new diketopyrrolopyrrole-based probe for sensitive and selective detection of sulfite in aqueous solution, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015, 137, 1055-1060.
(13) Xiao-feng Yang*, Rui Ning, Li-jun Xie, Yu Cui, Yong-ling Zhang, Lu-yi Zheng, Macrocyclic compound as NMR chiral solvating agent for determination of enantiomeric excess of carboxylic acids, Bull. Chem. Soc. Jpn., 2013, 86, 987-989.
(14) Ye-Xin Li, Xiao-Feng Yang, Jin-Ling Miao, Guo-Xin Sun, Substitution position and vinylene bond geometry modulating the fluorescence solvatochromism and aggregation-induced emission of (9-anthryl)vinyl(1-pyrenyl)vinylbenzene isomers, J. Phys. Chem. C, 2016, 120, 21722-21729.
(15) Cui Yu, Yang Xiao-Feng, Yang,Cheng, Li, Ye-Xin, Chen, Guo-Zhu, Sun, Guo-Xin, Solvent extraction of U(VI) by N,N-dimethyl-N', N'-dioctylsuccinylamide and N,N-dimethyl-N', N'-didecylsuccinylamide in cyclohexane, Nuclear Science and Techniques, 2016, 27, (3).
(16) Tianyu Jiang, Xiaofeng Yang, Xingye Yang, Mingliang Yuan, Tianchao, Zhang, Huateng Zhang, Minyong Li, Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitutionfor Renilla luciferase, Org. Biomol. Chem., 2016, 14, 5272-5281.
(17) Ye-Xin Li, Xiao-Feng Yang, Jin-Ling Miao, Zhen-Wei Zhang, Guo-Xin Sun, Effects of substitution position on crystal packing, polymorphism and crystallization-induced emission of (9-anthryl)vinylstyrylbenzene isomers, CrystEngComm., 2016, 18, 2098-2104.
(18) Chaoxia Guo, Xiaofeng Yang, Xiuxia Yang, Wenxue Zhu, Meishan Pei, Guangyou Zhang, Fluorescent probes for Cu²⁺, Hg²⁺and amino acids in aqueous solutions based on two mechanisms Sensors and Actuators B: Chemical, 2014, 205, 345-351.
(18) Chaoxia Guo, Xiaofeng Yang, Xiangyong Wang, Meishan Pei, Guangyou Zhang, Highly sensitive detection of Hg2+ in aqueous solution using cationic polythiophene derivatives, New J. Chem.,2013, 37, 4163-4169.

教学及研究生培养情况 主讲课程：《有机化学》、《有机化学专题》、《有机合成化学》和《有机化学实验》等课程。主编《有机化学学习指导》（教育部十二五规划教材）和《有机化学辅导及习题精解》（高鸿宾第四版）两部教材，参编教育部十二五规划教材《有机化学》。

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