· 求学经历：

2016.12-2017.12， 法国原子能委员会(CEA) ，药物化学， 访问学者，导师： Frederic Taran 教授

2016.1-至今，山东理工大学化学工程学院，副教授

2013.11-2014.11，法国原子能委员会(CEA)和牛津大学，有机化学，博士后，导师：FredericTaran 教授和 Véronique Gouverneur 教授

2013.10-2015.12，山东理工大学化学工程学院，讲师

2012.3-2013.11，华东师范大学绿色化学与化工过程绿色化重点实验室，有机化学，博士后，导师：姜雪峰研究员

2009.5-2010.4，美国 GlaxoSmithKline (葛兰素史克) 研发部，访问学者

2006.9-2012.3，华东理工大学精细化工研究所，应用化学，博士，导师：童晓峰教授和王利民教授

2002.9-2006.7，曲阜师范大学化学与化工学院，学士。

·荣誉称号：

首批“山东省优青”，

山东理工大学“双百工程”三层次人才

·特定职务：

·社会兼职：

· 主讲课程

有机化学，精细有机化学

· 科研方向

1. 金属导向的有机合成方法学研究

2. 18F,13C 标记的 PET药物研发以及在医药领域中的创新应用

3. 精细化工产品和医药中间体的合成路线以及合成工艺的研发

·学术成就

· 科研项目

1. 钯催化还原偶联构建 Csp2-Csp3 键反应的研究及其在天然产物全合成中的应用国家自然科学基金青年基金，**

2. 钯催化非活化烷基卤代烃构建Csp2-Csp3 键的偶联反应方法学及其机理研究，山东省属高校优秀青年基金，ZR2015JL005

3. 非活化 Csp3-Csp3 键绿色化构建方法研究， 山东省自然科学基金面上基金， ZR2018MB008

4. 钯催化非活化烷基卤代烃构建碳碳键反应方法学研究，中国博士后面上基金一等资助，2016M590736

5.基于 Ramberg-Bäcklund 反应策略的天然产物全合成，中国博士后面上基金二等资助： 2012M520858

6.钯催化非活化烷基卤代烃构建碳碳键反应方法学研究，山东省博士后创新项目专项资金一等资助，**2

7.中央高校基本科研业务费专项资金（华东师范大学）

8.山东理工大学青年教师发展支持计划

9.山东理工大学博士启动基金，2013

· 论著专利

2018 年

37. J.Cui, J. Song, Q.Liu, H. Liu,* and Y. Dong.* Transition-Metal-Catalyzed

Cyanationby Using an Electrophilic Cyanating Agent, N-Cyano-N-phenyl-p-

toluenesulfonamide(NCTS). Chem. Asian J. 2018, 13, 482-495. (SCI 二 区 IF = 4.083)

36. J. Li, X. Chi, L. Meng, L. Jiao, W.Shang, P. Wang, D. Zhang, Y. Dong, Q. Liu,* and H. Liu*. Palladium-Catalyzed Heck-Type Cascade Cyclization of(Z)-1-Iodo-1,6- dienes with N-Tosyl Hydrazones. Org. Biomol. Chem., 2018,DOI: 10.1039/C8OB01821A. (SCI 二区)IF = 3.56

35. H. Liang, L. Meng, X.Chi, S. Yao, H. Chen, L. Jiao, Q. Liu, D. Zhang, H. Liu,*

and Y. Dong*.Palladium/Copper Co-catalyzed Cascade Metallo-ene/Sonogashira Coupling Reactionof Allenamides. Asian J. Org. Chem., 2018, 7, 1793-1796. (SCI 三区IF=2.788)

34. J. Song, J. Cui, H. Liang, Q. Liu, Y. Dong, and H. Liu*. Palladium-Catalyzed

Direct OxidativeEsterification of Indoles atthe C3 Position: A Novel Prospect for

C(sp2)-H Acyloxylation. Asian J. Org.Chem., 2018, 7, 341-345. (SCI 三区IF=2.788)

33.J. Song, Q. Liu, H. Liu,* andX. Jiang.* Recent Advances in Palladium-Catalyzed

Carboxylation with CO2. Eur. J. Org. Chem.,2018, 6，696-713. (SCI 三区 IF= 2.834)

2017 年

32. X. Dong, J. Cui, J. Song, Y. Han, Q. Liu, Y. Dong and Hui Liu*.Palladium- catalyzed intramolecular reductive olefin hydrocarbonation: benzylichydrogen serving as a new hydrogen donor. Chem. Commun., 2017, 53, 4903-4906. (FrontCover, SCI 一区)

31.F. Yan,H. Liang, J. Song, J. Cui, Q. Liu, S. Liu, P. Wang, Y. Dong* and H. Liu*.

Palladium-CatalyzedCyclization-Heck Reaction of Allenamides: An Approach to 3-Methylene-5-phenyl-1,2,3,4-tetrahydropyridine Derivatives. Org. Lett.,2017, 19, 86-

89. (SCI 一区)

30. H. Liang, F. Yan, X. Dong, Q. Liu, X. Wei, S. Liu, Y. Dong*, H. Liu*.

Palladium-Catalyzed Cascade Metallo-Ene/Suzuki Coupling Reaction of

Allenamides. Chem. Commun., 2017, 53, 3138-3141. (SCI一区)

29. J.Li, Y. Hu, D.Zhang, Q. Liu*, Y. Dong andH. Liu*. Transition-Metal-

Catalyzed Reactions InvolvingOximes. Adv. Synth. Catal., 2017, 356, 710-771. (SCI

一区)

28. X. Dong, Q. Liu*, Y. Dong and H. Liu*, Transition-Metal-Catalyzed Electrophilic

Amination:Application of O-Benzoylhydroxylamines in the Construction of the C-N

Bond. Chem.Eur. J., 2017, 23, 2481-2511. (Frontispiece, SCI 二区)

28. J. Cui, H. Wang, J. Song,X. Chi, L. Meng, Q. Liu, D. Zhang, Y. Dong and H.

Liu*.Copper(I)-Catalyzed 5-exo-trig RadicalCyclization/Borylation of Alkyl Halides: Access to Functionalized PyrrolidineDerivates. Org. Biomol. Chem., 2017, 15, 8508-8512. (SCI 二区)IF = 3.56

27. X. Dong, Y. Hou, F. Meng,H-B. Liu and H. Liu*. RecentAdvances on Alkyl-

HeckReaction. Chin. J. Org. Chem., 2017, 37, 1088-1098.(Invited Paper)

2016 年

26. H. Liu, D. Audisio, L. Plougastel, E. Decuypere, V. Gouverneur, and F. Taran.

Ultrafast Click Chemistry with Fluorosydnones. Angew. Chem. Int. Ed., 2016, 55,

12073-12077. (SCI 一区)

25.J. Li, W. Yang, F. Yan, Q. Liu, P. Wang, Y. Li, Y. Zhao, Y. Dong* and H. Liu*. Pd-

Catalyzed Oxidative Isomerization ofPropargylic Acetates: Highly Efficient Access to α-Acetoxyenones via Alkenyl Csp2-O Bond-Forming Reductive Elimination from PdIV. Chem.Comm., 2016, 52, 10644-10647. (SCI 一区)

24. X. Dong, Y. Han, F. Yan,Q. Liu*, P. Wang, K. Chen, Y. Li, Z. Zhao, Y. Dong, and

H.Liu*. Palladium-Catalyzed 6-Endo Selective Alkyl-Heck Reactions:Access to 5-Phenyl-1,2,3,6-tetrahydropyridine Derivatives. Org. Lett., 2016, 18, 3774-3777. (SCI 一区)

23. H. Liang, H. Liu* and X. Jiang. Synlett, 2016, 27, 2774-2782.(Invited Paper)

2015 年

22. Q.Liu, X. Dong, J. Li,J. Xiao, Y. Dong* andH. Liu*. Recent Advances on

PalladiumRadical Involved Reactions. ACS Catal., 2015, 5, 6111-6137. (Invited

Review, SCI 一区)

21. E. Decuypere, S. Specklin, S. Gabillet, D. Audisio, H. Liu, L. Plougastel, S.

Kolodych, F. Taran. Copper(I)-Catalyzed Cycloaddition of4-Bromosydnones and Alkynes for the Regioselective Synthesis of1,4,5-Trisubstituted Pyrazoles. Org. Lett.,

2015, 17, 362-365. (SCI 一区)

2014 年以前：

20. H. Liu, J. Wei, Z. Qiao, Y. Fu, X. Jiang*. Palladium-Catalyzed Intramolecular

ReductiveCross-Coupling of Csp2-Csp3 Bond Formation. Chem.Eur.J., 2014, 20,

8308-8313. (SCI 二区)

19.H. Liu, M. Feng, X. Jiang*.Unstrained Carbon-Carbon Bond Cleavage. Chem.

Asian J., 2014,9, 3360-3382. (SCI 二区)

18.H. Liu, X. Jiang*.Pd-Catalyzed Reactions from Unactivated Csp3-I Bond. Pure

and AppliedChemistry, 2014, 85, PAC.2014.5032.

17.Z. Qiao,§H. Liu,§ X.Xiao, Y. Fu, J. Wei, Y. Li*and X. Jiang*. Efficient Access to 1, 4-Benzothiazine: Palladium-CatalyzedDouble C-S Bond Formation Using Na2S2O3asSulfuration Reagent. Org. Lett., 2013‚ 15‚ 2594-2597. (SCI 一区)

16. H. Liu, Z. Gu and X. Jiang*. Direct Trifluoromethylation of C-H Bond. Adv.

Synth. Catal.,2013, 355, 617-626. (SCI 一区)

15. H. Liu, Xuefeng Jiang*.Transfer of Sulfur: From Simple to Diverse. Chem.

Asian J., 2013, 8, 2546-2563. (SCI 二区)

14. H. Liu, X. Jiang*. Mechanistic Insight to the ReactionPathway of Aerobic

OxidativeC-C Bond Cleavage of α-HydroxyKetones. Synlett, 2013, 24, 1311-1315.

13. L. Wang,J. Huang, S. Peng, H. Liu,X. Jiang* and J. Wang*. Palladium-Catalyzed Oxidative Cycloaddition via C–H/N–H Activation: Access toBenzazepines. Angew. Chem. Int. Ed., 2013, 52, 1768-1772. (SCI 一区)

12. H. Liu, C. Dong, Z. Zhang, P. Wu and X. Jiang*. Transition-Metal-Free Aerobic

Oxidative Cleavage of C-C Bonds in α-Hydroxy Ketones and Mechanistic Insight to

the Reaction Pathway. Angew. Chem. Int. Ed., 2012, 51, 12570-12574. (SCI 一区)

11. H. Liu, Z. Qiao and X. Jiang*. Palladium-Catalyzed Atom Transfer Radical

Cyclizationof Unactivated Alkyl Iodide. Org. Biomol.Chem., 2012, 10, 7274-7277.

10.X. Jiang*, H. Liu and Z. Gu. Carbon-Halogen Bond Formation by the ReductiveElimination of PdII Species. Asian J. Org. Chem., 2012, 1, 16-24.

9. K. Li, J. Hu, H.Liu and X. Tong*.Amine-catalyzed formal (3+3) annulations of 2- (acetoxymethyl)buta-2,3-dienoatewith sulfur ylides: synthesis of 4H-pyrans bearing a vinyl sulfide group. Chem. Commun., 2012, 48, 2900-2902.

8. W. Li, H. Liu,X. Jiang*, J. Wang*. Enantioselective OrganocatalyticConjugate Addition of Nitroalkanes to Electrophilic 2-Iminochromenes. ACS Catal., 2012, 2, 1535-1538.

7. X.Jiang*, L. Shi, H. Liu, Akbar H. Khan and Jason S. Chen. Gas Extrusion inNatural Products Total Synthesis. Org.Biomol. Chem., 2012, 10, 8383-8392.

6. P.Wu, H. Liu, X. Tong*. Synthesis of 3-pyrroline via domino Heck-aza-Michael reaction. Tetrahedron Lett., 2012, 53, 4673-4675.

5. Q. Ren, J. Huang, L. Wang,W. Li, H. Liu, X. Jiang* andJ. Wang*. Highly Efficient Assemblyof 3Hydroxy Oxindole Scaffold via a Catalytic Decarboxylative [1,2]-Addition Strategy. ACS Catalysis, 2012, 2, 2622-2625.

4. H. Liu,C. Li, D. Qiu* and X. Tong*. Palladium-CatalyzedCycloisomerizations of (Z)-1-Iodo-1,6-dienes: Iodine Atom Transfer andMechanistic Insight to Alkyl Iodide Reductive Elimination. J. Am. Chem. Soc., 2011,133, 6187-6193.

3.H. Liu, C. Chen, L. Wang andX. Tong*. Pd(0)-Catalyzed Iodoalkynationof

Norbornene Scaffolds: The Remarkable Solvent Effect onReaction Pathway. Org. Lett., 2011, 13, 5072-5075.

2. H. Liu,L. Wang and X. Tong*.Palladium-Catalyzed Heck-type Reaction of Oxime Ether Bearing a Pendant Vinyl Iodide Moiety. Chem.Comm., 2011, 47,12206-12208.

1. H. Liu,J. Yu, L. Wang, X. Tong*.Cyclization–oxidation of 1,6-enyne derivatived from Baylis–Hillman adducts via Pd(II)/Pd(IV)-catalyzed reactions:stereoselective synthesis of multi-substituted bicyclo[3.1.0] hexanes andinsight into reaction pathways. TetrahedronLett., 2008, 49, 6924-6928.

授权专利：

1.姜雪峰，汪舰，刘会，李文军，3,3-二取代-2-氧化吲哚类化合物的不对称合成方法。

专利授权号：ZL 2012 1 **.9

2. 姜雪峰，刘会，乔宗君，一种 2,3-二氢-[1,4]-苯并噻嗪类化合物的合成方法。专利授权号：ZL 2013 1 **.6

著作：

1. Hui Liu,X. Jiang*.

Application of Zinc catalysts in Total Synthesis in ZincCatalysis-Applications in Organic Synthesis Ed. Stephan Enthaler and Xiao-FengWu, Wiley-VCH, 2014, 219- 273.

2.X. Jiang*, Hui Liu

Electrophilic Cyclizations in Comprehensive Organic Synthesis2nd Edition, Ed. Gary Molander andPaul Knochel, Oxford: Elsevier, 2014, Vol 4, 412-497.

联系方式： 电话： 邮箱： huiliu1030@sdut.edu.cn, huiliu1030@163.com

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