姓名 | 肖海滨 | 性别 | 男 | 出生 年月 | 1988 年 05 月 | |
职称 | 讲师 | 职务 | 政治 面貌 | 中共党员 |
· 求学经历:
2018 年 01 月-至今山东理工大学 讲师
2013 年9 月-2017 年 12 月 山东师范大学 分析化学 博士
2011 年9 月-2013 年 6 月 山东师范大学 分析化学 硕士
2006 年9 月-2010 年 6 月 山东师范大学 化学工程与工艺 学士
· 荣誉称号:
2019 年度山东理工大学教师教学质量奖
2019 年山东省自然科学奖二等奖(第四位)
· 特定职务:
· 社会兼职:
· 主讲课程
《分析化学》、《分析化学实验》、《仪器分析》、《仪器分析实验》
· 科研方向
1、荧光发光材料的设计、合成;
2、荧光传感器用于细胞及活体内生物活性分子的检测。
· 学术成就
本人专业研究方向为光分析化学与探针,主要从事:有机分子探针的设计、合成;生物活性分子的荧光成像、检测等。对分析化学、仪器分析等专业课程比较熟悉。研究成果获得 2019 年山东省自然科学奖二等奖(第四位),已经发表本学科领域SCI论文近 20 余篇,其中以第一作者或通讯作者发表论文 11 篇, 并参与申请已授权专利 2 项。
·科研项目
1、国家自然科学基金青年基金项目,“糖尿病诱导肝损伤模型中活性氧物种的荧光/光声双模态成像研究”,2020.01-2022.12,主持,26万。
2、山东理工大学博士启动基金,“细胞及活体内过氧化氢的荧光/光声双模态成像”,2018,主持,10万。
·论著专利
1. HaibinXiao#, Wen Zhang#, Ping Li*, Wei Zhang, Xin Wang and Bo Tang*, Versatile fluorescentprobes for imaging the superoxide anion in living cells and in vivo. Angew. Chem. Int. Ed., 2020, 59(11), 4216-4230.
2. Yaqi Dong, Haibin Xiao*, Lingbao Xing, Chuanchen Wu, Jin Zhou, Ziyan Zhou,Yuying Liu*, Shuping Zhuo and PingLi*, Two-photon fluorescencevisualization of lysosomal pH changes during mitophagy and cell apoptosis. Talanta, 2020, 209, 120549.
3. HaibinXiao, Yaqi Dong, Jin Zhou, ZiyanZhou, Xiaozhong Wu, Rongzhou Wang, Zhichao Miao, Yuying Liu* and Shuping Zhuo*, Monitoringmitochondrial pH with a hemicyanine-based ratiometric fluorescent probe.Analyst, 2019, 144(10), 3422-3427.
4. . Haibin Xiao#, Ruilin Zhang# , Chuanchen Wu, Ping Li*, Wen Zhang*and Bo Tang, A newpH-sensitivefluorescent probe forvisualization ofendoplasmic reticulum acidificationduring stress. Sensor. Actuat. B-Chem., 2018, 273, 1754- 1761.
5. HaibinXiao, Chuanchen Wu, Ping Li* and Bo Tang*, Simultaneous fluorescencevisualization of endoplasmic reticulum superoxide anion and polarity inmyocardial cells and tissue. Anal. Chem., 2018, 90, 6081-6088.
6. . Haibin Xiao, Chuanchen Wu, Ping Li*, Wen Gao, Wen Zhang, Wei Zhang,Lili Tong and Bo Tang*, Ratiometric photoacoustic imagingof endoplasmic reticulum
polarity in injured liver tissues of diabetic mice. Chem.Sci., 2017, 8(10), 7025-7030.
7. . Haibin Xiao, Xiao Liu, Chuanchen Wu, YaohuanWu, Ping Li*, Xiaomeng Guoand Bo Tang*, A new endoplasmicreticulum-targeted two-photon fluorescent probe for imaging of superoxide anionin diabetic mice. Biosens. Bioelectron., 2017, 91, 449-455.
8. 肖海滨, 李平*, 张雯, 张卫, 唐波*, 有机分子荧光探针成像检测线粒体内 ROS
的研究进展,中国科学: 化学, 2017, 47, 955-972.
9 . Haibin Xiao, Ping Li*, Shan Zhang, Wei Zhang, Wen Zhang and Bo Tang*, Simultaneousfluorescence visualization of mitochondrial hydrogen peroxide and zinc ions inlive cells and in vivo. Chem. Commun., 2016, 52(86), 12741-12744.
10 . Haibin Xiao, Ping Li, Xiufen Hu,Xiaohui Shi, Wen Zhang and Bo Tang*, Simultaneous fluorescence imaging ofhydrogen peroxide in mitochondria and endoplasmic reticulum during apoptosis.Chem. Sci., 2016, 7(9), 6153-6159.
11 . Haibin Xiao#, Ping Li#, Wei Zhang and Bo Tang*, An ultrasensitive near- infrared ratiometric fluorescentprobe for imaging mitochondrial polarity in live cells and in vivo. Chem. Sci.,2016, 7(2), 1588-1593.
其他论文:
1. Ping Li, LuLiu, Haibin Xiao, Wei Zhang, Lulin Wang and Bo Tang*, A New Polymer nanoprobe based on chemiluminescenceresonance energy transfer for ultrasensitive imaging of intrinsic superoxideanion in mice. J. Am. Chem. Soc., 2016, 138 (9), 2893-2896.
2. Wei Zhang, Wei Liu,Ping Li*, Haibin Xiao, Hui Wang andBo Tang*, A fluorescence nanosensorfor glycoprotein via molecularly imprinted spatital structure and boronate affitity. Angew. Chem. Int. Ed., 2014, 53(46), 12489-12493
3. Ping Li,Haibin Xiao, Yinfang Cheng, Wen Zhang, Fang Huang, Wei Zhang, Hui Wang and Bo Tang*, Anear-infrared-emitting fluorescent probe for monitoring mitochondrial pH. Chem.Commun., 2014, 50(54), 7184-7187.
4. Wen Zhang, Xin Wang, PingLi*, Haibin Xiao, Wei Zhang, Hui Wang, and Bo Tang*. Illuminating superoxide anion and pH enhancements inapoptosis of breast cancer cells induced by mitochondrial hyperfusion using anew two-photon fluorescence probe. Anal. Chem., 2017, 89, 6840-6845.
5. Lu Li#,Ping Li#, Juan Fang, Qingling Li, Haibin Xiao, Hui Zhou, and Bo Tang*. Simultaneous quantitation of Na+ andK+ in single normal and cancer cells using a new near-infrared fluorescentprobe. Anal. Chem., 2015, 87, 6057-6063.
6. Ping Li,Shan Zhang, Nannan Fan, Haibin Xiao, Wen Zhang,Wei Zhang, Hui Wang, and Bo Tang*. Quantitative fluorescence ratio imaging of intralysosomalchloride ions with single excitation/dual maximum emission. Chem. Eur. J., 2014, 20,
11760-11767.
7. Ping Li, Wen Zhang, Kexiang Li, Xiao Liu, HaibinXiao, Wei Zhang, and Bo Tang*. Mitochondria-targetedreaction-based two-photon fluorescent probe for imaging of superoxide anion inlive cells and in vivo. Anal. Chem., 2013, 85, 9877- 9881.
授权专利:
1、唐波;李平;肖海滨,一种对环境极性敏感的近红外荧光探针及其合成方法和应用(ZL**8987.9)。
2、唐波;李平;肖海滨;张雯,具有大斯托克斯位移的近红外荧光染料及合成方法与应用(ZL**6444.X)。
联系方式:电话:**628 邮箱:haibinxiao@sdut.edu.cn 课题组网址: