教育背景：
2002/09– 2006/06，湖南师范大学，生命科学学院，基地班，学士
2006/09– 2012/12，湖南师范大学，生命科学学院，微生物学，博士
2008/12 – 2010/11，德国德累斯顿工业大学，基因组系，联培博士
工作经历：
2013/05 – 2017/05，山东大学，生命科学学院，博士后
2016/03 – 2018/06，山东大学，微生物技术国家重点实验室，科研助理
2018/07 –至今， 山东大学，微生物技术研究院/国家重点实验室，教授
研究方向：
1.微生物合成生物学
2.DNA重组技术开发
3.微生物药物生物合成途径优化
4.多效植物促生细菌的构建及改良
科研项目：
1.国家重点研发计划子课题（2019YFA**），非天然噬菌体的设计合成----非天然碱基在噬菌体中的复制和转录体系构建，2020/1-2024/12，93万元，主持。
2.国家重点研发计划子课题（2018YFA**），放线菌底盘适配性机理与产物高产机制研究----高效基因编辑与异源表达技术开发，2019/7-2024/6，73万元，主持。
3.山东省自然科学基金重大基础研究项目（ZR2019ZD22），高效表达非洲猪瘟病毒多抗原的伪狂犬载体构建及评价，2019/12-2024/12，164万元，主持。
4.山东省泰山****青年专家，100万元，2019/01-2023/12，主持。
5.山东大学齐鲁青年****，100万元，2018/07-2023/06，主持。
6.国家自然科学基金青年基金项目，**，植物促生土著链霉菌的人工改良以增强其杀线虫活性，25万元，2018/01?2020/12，主持。
7.中国博士后科学基金特别资助项目，2015T80710，改造埃博霉素生物合成途径以提高单一组分的产量和纯度，15万元，2015/07-2017/01，主持。
8.山东省博士后创新项目，，通过诱发细胞内DNA双链断裂来直接克隆基因组DNA，2万元，2013/10-2015/06，主持。
代表性论文：
1.Song, C.¹, Luan, J.¹, Cui, Q., Duan, Q., Li, Z., Gao, Y., Li, R., Li, A., Shen, Y., Li, Y., Stewart, A. F., Zhang, Y.*, Fu, J.*&Wang, H.*, Enhanced heterologous spinosad production from a 79-kb synthetic multi-operon assembly,ACS Synth. Biol., 2019, 8(1), 137-147.
2.Zhang, Y.¹, Liu, R.¹, Tian, K.¹, Wang, Z.¹, Yang, X., Gao, D.,Zhang, Y.,Fu, J.*,Wang, H.* & Zhao, J.*, Fiber2 and hexon genes are closely associated with the virulence of the emerging and highly pathogenic fowl adenovirus 4,Emerg. Microbes Infect., 2018, 7(1), 199.
3.Jing, X.¹, Cui, Q.¹, Li, X., Yin, J., Ravichandran, V., Pan, D., Fu, J., Tu, Q.,Wang, H.*, Bian, X.*& Zhang, Y.*, EngineeringPseudomonas protegensPf-5 to improve its antifungal activity and nitrogen fixation,Microb. Biotechnol., 2018, Epub ahead of print.
4.Wang, H.¹, Li, Z., Jia, R., Yin, J., Li, A., Xia, L., Yin, Y., Muller, R., Fu, J.*, Stewart, A. F.* & Zhang, Y.*, ExoCET: exonucleasein vitroassembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes,Nucleic Acids Research, 2018, 46(5), e28.
5.Wang, H.¹, Li, Z.¹, Jia, R., Hou, Y., Yin, J., Bian, X., Li, A., Muller, R., Stewart, A. F.*, Fu, J.* & Zhang, Y.*, RecET direct cloning and Redαβ recombineering of biosynthetic gene clusters, large operons or single genes for heterologous expression,Nature Protocols, 2016, 11(7), 1175-1190.
6.Wang, H.¹, Bian, X., Xia, L., Ding, X., Muller, R., Zhang, Y.*, Fu, J.* & Stewart, A. F.*, Improved seamless mutagenesis by recombineering usingccdBfor counterselection,Nucleic Acids Research, 2014, 42(5), e37.
7.Wang, H.¹, Yao, T., Cai, M., Xiao, X., Ding, X. & Xia, L.*, A genome walking strategy for the identification of nucleotide sequences adjacent to known regions,Biotechnology letters, 2013, 35(2), 279-284.
8.Fu, J.¹, Bian, X.¹, Hu, S.,Wang, H., Huang, F., Seibert, P. M., Plaza, A., Xia, L., Muller, R.*, Stewart, A. F.* & Zhang, Y.*, Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting,Nature Biotechnology, 2012, 30(5), 440-446.
9.Rostovskaya, M.¹, Fu, J., Obst, M., Baer, I., Weidlich, S.,Wang, H., Smith, A. J. H., Anastassiadis, K.*& Stewart, A. F.*, Transposon-mediated BAC transgenesis in human ES cells,Nucleic Acids Research, 2012, 40(19), e150.
10.Zhang, W.¹, Fu, J.¹, Liu, J.,Wang, H., Schiwon, M., Janz, S., Schaffarczyk, L., von der Goltz, L., Ehrke-Schulz, E., Domer, J., Solanki, M., Boehme, P., Bergmann, T., Lieber, A., Lauber, C., Dahl, A., Petzold, A., Zhang, Y.*, Stewart, A. F.* & Ehrhardt, A.*, An engineered virus library as a resource for the spectrum-wide exploration of virus and vector diversity,Cell Reports, 2017, 19(8), 1698-1709.
11.Zhang, W.¹, Fu, J., Liu, J.,Wang, H., Schulz, E., Solanki, M., Boehme, P., Gebbing, M., Bergmann, T., Doerner, J., Stewart, A. F. & Ehrhardt, A.*, High-throughput cloning and tagging of an engineered adenovirus-library empowers vector diversity for broad applications,Molecular Therapy, 2015, 23, S21.
12.Bian, X.¹, Tang, B.¹, Yu, Y., Tu, Q., Gross, F.,Wang, H., Li, A., Fu, J., Shen, Y., Li, Y., Stewart, A. F., Zhao, G., Ding, X.*, Muller, R.* & Zhang, Y.*, Heterologous production and yield improvement of epothilones inBurkholderialesstrain DSM 7029,ACS Chemical Biology, 2017, 12(7), 1805-1812.
13.Yin, J.¹,Wang, H., Li, R., Ravichandran, V., Bian, X., Li, A., Tu, Q., Stewart, A.F., Fu, J.* & Zhang, Y.*, A practical guide to recombineering inPhotorhabdusandXenorhabdus,Current Topics in Microbiology and Immunology, 2017.
14.Ravichandran, V.¹, Zhong, L.,Wang, H., Yu, G., Zhang, Y.*& Li, A.*, Virtual screening and biomolecular interactions of CviR-based quorum sensing inhibitors against chromobacterium violaceum,Front. Cell Infect. Microbiol., 2018, 8, 292.
15.Liu, Q.¹, Shen, Q.¹, Bian, X., Chen, H., Fu, J.,Wang, H., Lei, P., Guo, Z., Chen, W.*, Li, D.* & Zhang, Y.*, Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster inBacillus subtilisvia Red/ET recombineering,Scientific Reports, 2016, 6, 34623.
16.Jiang, B.¹, Zhang, R., Feng, D., Wang, F., Liu, K., Jiang, Y., Niu, K., Yuan, Q., Wang, M.,Wang, H., Zhang, Y. & Fang, X.*, A Tet-on and Cre-loxP based genetic engineering system for convenient recycling of selection markers inPenicillium oxalicum,Frontiers in Microbiology, 2016, 7, 485.
17.Zhu, L.¹, Yue, X., Han, K., Li, Z., Zheng, L., Yi, X.,Wang, H., Zhang, Y. & Li, Y.*, Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes inMyxococcus xanthus,Microbial Cell Factories, 2015, 14, 105.
18.Bian, X.¹, Huang, F.,Wang, H., Klefisch, T., Muller, R.* & Zhang, Y.*, Heterologous production of glidobactins/luminmycins inEscherichia coliNissle containing the glidobactin biosynthetic gene cluster fromBurkholderiaDSM7029,Chembiochem, 2014, 15(15), 2221-2224.
19.Yu, F.¹, Jing, X., Li, X.,Wang, H., Chen, H., Zhong, L., Yin, J., Pan, D., Yin, Y., Fu, J., Xia, L., Bian, X., Tu, Q. & Zhang, Y., Recombineering Pseudomonas protegens CHA0: An innovative approach that improves nitrogen fixation with impressive bactericidal potency,Microbiol. Res., 2019, 218, 58-65.
获奖情况：
1.教育部自然科学二等奖（第二位），2019/12.
2.山东大学（青岛）十佳书院导师，2019/09
3.山东大学重大科研突出成绩奖励，2017/12.
4.微生物技术国家重点实验室青年人才学术交流会优秀报告三等奖，2017/12.
5.中国微生物学会学术年会优秀学术论文交流奖，2014/08.