姓名 贾继辉 性别 男 出生年月 1963.01 导师聘任时间 2004.6（博导）
职务 院 长 职称 教授 学历 研究生 学位 博士
指导研究生类型 ?博士学位研究生 ?学术学位研究生 ?专业学位研究生 暂无护理学博士招生计划
工作单位名称（全称）： 山东大学护理学院
研究方向及领域 1、护理教育学 2、健康关怀学

科研项目 1、国家重大科技计划：端粒相关蛋白在基因表达调控及细胞分化中的作用（No2012CB911202,2012.01-2016.08）
2、国家自然科学基金项目：H.pylori 诱导细胞逃逸衰老和上皮间质转化促进恶性演变的分子机制（No. **,2012.01-2015.12）
3、国家自然科学基金项目：FoxM1调控hTERT表达介导胃癌细胞逃逸
衰老的机制（No. **,2010.01-2013.12）


科研论文及著作 近三年贾继辉以通讯作者或共同通讯作者发表SCI收录科学论文 18篇，论文按发表时间排序， *表示通讯作者。 1. Sun Y, Li X, Li W, Zhao M, Wang L, Liu S, Zeng J, Liu Z, Jia J*（贾继辉）. Proteomic analysis of the function of SpoT in Helicobacter pylori anti-oxidative stress in vitro and colonization in vivo. J Cell Biochem. 113(11):3393-402. 2012
2. Liu Z*, Xu X, Chen L, Li W, Sun Y, Zeng J, Yu H, Chen C, Jia J*（贾继辉）. Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and
p38 MAPK pathways in gastric epithelial cell. J Cell Biochem. 113(3):1080-6. 2012
3. Zhou Y, Wang G, Li Y, Liu Y, Song Y, Zheng W, Zhang N, Hu X, Yan S, Jia J*（贾继辉）. In vitro interactions between aspirin and amphotericin B against planktonic cells and
biofilm cells of Candida albicans and C. parapsilosis. Antimicrob Agents Chemother.56(6):3250-60. 2012
4. Xu X, Liu Z, Fang M, Yu H, Liang X, Li X, Liu X, Chen C, Jia J*（贾继辉）. Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src/MEK/ERK/c-Myc pathway: implication for progression of gastric diseases. Exp Biol Med (Maywood). 237(4):435-41. 2012
5. Liu Z, Li Q, Li K, Chen L, Li W, Hou M, Liu T, Yang J, Lindvall C, Björkholm M, Jia J*（贾继辉）, . Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene. 2012 Oct 8. doi: 10.1038/onc.2012.441. [Epub ahead of print] 2012
6. Han M, Dai J, Zhang Y, Lin Q, Jiang M, Xu X, Liu Q*, Jia J*（贾继辉）. Support vector machines coupled with proteomics approaches for detecting biomarkers predicting
chemotherapy resistance in small cell lung cancer. Oncol Rep. 28(6):2233-8. 2012
7. Han M, Xu J, Bi Y, Jiang M, Xu X, Liu Q*, Jia J*（贾继辉）. Primary tumor regulates the pulmonary microenvironment in melanoma carcinoma model and
facilitates lung metastasis. J Cancer Res Clin Oncol. 139(1):57-65. 2013
8. Shao C, Zhou Y, Sun Y, Wang H, Qu W, Yu H, Chen C, Jia J*（贾继辉）. Analysis of aztreonam-inducing proteome changes in nondividing filamentous Helicobacter pylori. Curr Microbiol. 65(1):108-15. 2012
9. Sun HQ, Zhang JY, Zhang H, Zou ZS, Wang FS*, Jia JH*（贾继辉）.Increased Th17 cells contribute to disease progression in patients with HBV-associated liver cirrhosis. J Viral Hepat. 19(6):396-403. 2012
10. Li W, Zhao L, Zang W, Liu Z, Chen L, Liu T, Xu D*, Jia J*（贾继辉）. Histone demethylase JMJD2B is required for tumor cell proliferation and survival and
is overexpressed in gastric cancer. Biochem Biophys Res Commun. 416(3-4):372-8. 2011
11. Wang H, Sun Y, Liu S, Yu H, Li W, Zeng J, Chen C, Jia J*（贾继辉）. Upregulation of progranulin by Helicobacter pylori in human gastric epithelial cells via p38MAPK
and MEK1/2 signaling pathway: role in epithelial cell proliferation and migration.
FEMS Immunol Med Microbiol. 63(1):82-92. 2011
12. Zhao Y, Zhou Y, Sun Y, Yu A, Yu H, Li W, Liu Z, Zeng J, Li X, Chen C, Jia J*（贾继辉）. Virulence factor cytotoxin-associated gene A in Helicobacter pylori is downregulated by interferon-γin vitro. FEMS Immunol Med Microbiol. 61(1):76-83. 2011
13. Qu W, Zhou Y, Sun Y, Fang M, Yu H, Li W, Liu Z, Zeng J, Chen C, Gao C*, Jia J*（贾继辉）. Identification of S-nitrosylation of proteins of Helicobacter pylori in response to nitric oxide stress. J Microbiol. 49(2):251-6. 2011
14. Wang CM, Wang Y, Fan CG, Xu FF, Sun WS, Liu YG, Jia JH*（贾继辉）.miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma. Biochem Biophys Res Commun. 5;411(3):586-92. 2011
15. Li W, Ge Z, Liu C, Liu Z, Björkholm M, Jia J*（贾继辉）, Xu D*. Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cance. Mol Cancer. 9:132. 2010
16. Zeng J, Ge Z, Wang L Li Q, Wang N, Björkholm M, Jia J*（贾继辉）, Xu D *. The histone demethylase RBP2 is over-expressed in gastric cancer and its inhibition triggers senescence of cancer cells. Gastroenterology. 138(3):981-92. 2010
17. Zhao D, Liu Z*, Ding J, Li W, Sun Y, Yu H, Zhou Y, Zeng J, Chen C, Jia J*（贾继辉）. Helicobacter pylori CagA upregulation of CIP2A is dependent on Src and MEK/ERK pathways.
J Med Microbiol. 59(3):259-65. 2010
18. Liu S, Sun Y, Li W, Yu H, Li X, Liu Z, Zeng J, Zhou Y, Chen C, Jia J*（贾继辉）. The antibacterial mode of action of allitridi for its potential use as a therapeutic agent
against Helicobacter pylori infection. FEMS Microbiol Lett. 303(2):183-9. 2010


学术奖励、荣誉称号 1、优秀博士论文指导奖，山东大学，2011年。
2、优秀博士论文指导奖，山东大学，2012年。

备注 通讯地址 山东大学护理学院 邮政编码 250012
办公电话 E-mail jiajihui@sdu.edu.cn