【个人简介】 姓 名 赵宝祥
性 别 男
出生日期 1959-09-23
学 历 博士
职 称 教授 ( 博导 [聘任于2007])
学术身份
行政职务
学术团体兼职
研究类别 有机化学 ::
工作单位 有机化学研究所 ::
电 话
传 真
地 址
E-mail bxzhao@sdu.edu.cn




【学习及工作经历】 1978.10-1982.6 大连理工大学化学工程系学习（本科）
1983.9-1986.6 大连理工大学研究生院精细化工系学习（硕士研究生）
1986.7－1993.3 山东省化工研究院工作，工程师
1994.10－1998.3 日本名古屋大学，博士研究生，获得应用化学专业工学博士学位
1998.3－1999.9 山东大学化学院有机化学研究所，副教授
1999.10－2000.6 德国柏林工业大学有机化学研究所博士后研究员
2000.7－今 山东大学化学与化工学院有机化学研究所，教授
2003.7-2004.6 韩国昌原大学合成化学研究所博士后研究员

【主讲课程】 有机化学 （化学基地班，双语教学）
有机化学实验,
综合化学实验
有机合成新方法（研究生学位必修课）
合成化学（研究生必修课）

【研究领域和兴趣】 有机合成 荧光探针　药物化学，杂环化学, 化学生物学

【主要论著】 2018年

1. Miao-Fei Huang, Li-Na Chen, Jun-Ya Ning, Wen-Li Wu, Xiao-Dong He, Jun-Ying Miao*, Bao-Xiang Zhao*，
A new lipid droplets-targeted fluorescence probe for specific detection of SO2 derivatives in living cells,
Sensors and Actuators B 261 (2018) 196–202.


2. Long-Long Xi, Xue-Fei Guo, Chen-Liang Wang, Wen-Li Wu, Miao-Fei Huang, Jun-Ying Miao*, Bao-Xiang Zhao*,
A near-infrared ratiometric fluorescent probe for rapid and selective detection of hypochlorous acid in aqueous solution and living cells,
Sensors and Actuators B 255 (2018) 666–671.


3. Dong-Peng Li, Xian-Jing Han, Ze-Quan Yan, Yun Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,
A far-red ratiometric fluorescent probe for SO2 derivatives based on the ESIPT enhanced FRET platform with improved performance,
Dyes and Pigments 151 (2018) 95–101.


4. Li-Jie Zhang Jun-Ya Ning, Jun-Ying Miao, Jin-Ting Liu*, Bao-Xiang Zhao*,
A new ratiometric fluorescent probe for detecting endogenous HClO in living cells,
New J. Chem., 2018, 42, 2989--2993.

2017
1. Dong-Peng Li,Zhao-Yang Wang,Hao Su,Jun-Ying Miao* and Bao-Xiang Zhao*
Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform
Chem. Commun.,2017, 53, 577-58.
2. Shi-Li Shen,Xuan Zhao,Xiao-Fan Zhang,Xuan-Li Liu,Hao Wang,Yi-Ying Dai,Jun-Ying Miao and Bao-Xiang Zhao*
A mitochondria-targeted ratiometric fluorescent probe for hypochlorite and its applications in bioimaging
J. Mater. Chem. B, 2017, 5,289-295.
3. Wen-Li Wu, Han-Lin Ma, Miao-Fei Huang,Jun-Ying Miao,Bao-Xiang Zhao*
Mitochondria-targeted ratiometric fluorescent probe based on FRET for bisulfite
Sensors and Actuators B 241 (2017) 239–244.
4. Yan-Ru Zhang, Ying Liu, Xiao Feng, Bao-Xiang Zhao*
Recent progress in the development of fluorescent probes for the detection of hypochlorous acid
Sensors and Actuators B 240 (2017) 18–36.
5. Wen-Li Wu, Xuan Zhao, Long-Long Xi, Miao-Fei Huang, Wen-Hui Zeng, Jun-Ying Miao*, Bao-Xiang Zhao*
A mitochond ria-targetedfl uorescence probe for ratiometric detection of endogenous hypochlorite in the living cells
Analytica Chimica Acta 950 (2017) 178-183.
6. Shi-Li Shen, Jun-Ya Ning, Xiao-Fan Zhang, Jun-Ying Miao, Bao-Xiang Zhao*
Through-bond energy transfer-based ratiometric fluorescent probe for the imaging of HOCl in living cells
Sensors and Actuators B 244 (2017) 907–91
7. Qiong Yuan, Zhi-Min Zhao, Yan-Ru Zhang, Le Su, Jun-Ying Miao, Bao-Xiang Zhao*
A lysosome-targeted ratiometric fluorescent probe for detection of hypochlorous acid in living cells
Sensors and Actuators B 247 (2017) 736–741.
8. Li-Jie Zhang, Zhao-Yang Wang, Jin-Ting Liu, Jun-Ying Miao, Bao-Xiang Zhao*,
A rational design of ratiometric fluorescent probes based on new ICT/FRET platform and imaging of endogenous sulfite in living cells，
Sensors and Actuators B 253 (2017) 19–26.
9. Dong-Peng Li, Zhao-Yang Wang, Jie Cui, Xin Wang, Jun-Ying Miao，Bao-Xiang Zhao*，
A new ?uorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells，
Scientific RepoRts, 7:45294.


2016
1. Dong-Peng Li, Zhao-Yang Wang, Xiang-Jian Cao, Jie Cui, Xin Wang, Hao-Zhong Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,
A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells,
Chem. Commun., 52 (2016) 2760--2763.
2. Xiao Feng, Tao Zhang, Jin-Ting Liu, Jun-Ying Miao*, Bao-Xiang Zhao*,
A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria,
Chem. Commun. 52 (2016) 3131--3134.
3. Wen-Li Wu,Zhao-Yang Wang, Xi Dai, Jun-Ying Miao & Bao-Xiang Zhao*，
An effective colorimetric and ratiometric fluorescent probe based FRET with a large Stokes shift for bisulfite.
Scientific Reports,6:25315 (2016).
4. Yan-Ru Zhang, Zhi-Min Zhao, Jun-Ying Miao, Bao-Xiang Zhao*,
A ratiometric fluorescence probe based on a novel FRET platform for imaging endogenous HOCl in the living cells,
Sensors and Actuators B 229 (2016) 408–413.
5. Xi Dai, Tao Zhang, Jun-Ying Miao*, Bao-Xiang Zhao*,
A ratiometric fluorescent probe with DNBS group for biothiols in aqueous solution,
Sensors and Actuators B 223 (2016) 274-279.

6. Xi Dai, Zhao-Yang Wang, Zhi-Fang Du,Jun-Ying Miao,Bao-Xiang Zhao*,
A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging,
Sensors and Actuators B 232 (2016) 369–374.
7. Wen-Li Wu, Zhi-Min Zhao,Xi Dai, Le Su, Bao-Xiang Zhao,
A fast-response colorimetric and fluorescent probe for hypochlorite and its real applications in biological imaging
Sensors and Actuators B 232 (2016) 390–395
8. Jie Cui, Tao Zhang, Yi-Qing Sun, Dong-Peng Li, Jin-Ting Liu, Bao-Xiang Zhao,
A highly sensitive and selective fluorescent probe for H2S detection with large fluorescence enhancement
Sensors and Actuators B 232 (2016) 705–711,
9. Dong-Peng Li, Jin-Feng Zhang, Jie Cui, Xiao-Feng Ma, Jin-Ting Liu, Jun-Ying Miao,Bao-Xiang Zhao
A ratiometric fluorescent probe for fast detection of hydrogen sulfide and recognition of biological thiols
Sensors and Actuators B 234 (2016) 231–238
10. Li-Jie Zhang, Zhao-Yang Wang, Xiang-Jian Cao, Jin-Ting Liu, Bao-Xiang Zhao,
An effective ICT-based and ratiometric fluorescent probe for sensing sulfite
Sensors and Actuators B 236 (2016) 741–748
11. Xiang-Jian Cao, Li-Na Chen, Xuan Zhang, Jin-Ting Liu, Ming-Yu Chen,Qiu-Rong Wu, Jun-Ying Miao*, Bao-Xiang Zhao*,
A NBD-based simple but effective fluorescent pH probe for imaging of lysosomes in living cells，
Analytica Chimica Acta