研究经历：
研究工作：神经退行性疾病中（老年痴呆、帕金森症、ALS）的线粒体异常；Tau蛋白磷酸化机理；氧化应激（oxidative stress）在老年痴呆症发病过程中的作用；
博士期间研究工作：HIV-1分子流行病学（华中地区）；HIV-1耐药性突变的基因型检测；
其它曾参与工作：感染型HIV-1克隆株的构建；减毒痘苗病毒天坛株基础上的疫苗载体构建。
科研成果：
1.Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal Mitochondrial Dynamics-A Novel Therapeutic Target for Alzheimer's Disease? Mol Neurobiol. 2010 Jan 27
2.Bo Su, Xinglong Wang, Hyoung-gon Lee, Massimo Tabaton,George Perry, Mark A Smith, Xiongwei Zhu. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neuroscience Letters. 2009. 468:267-71
3.Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta. 2009. 1802:135-42
4.Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Mol Neurodegener. 2009; 4:32
5.Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15;29 (28):9090-103.
6.Luo M, Liu H, Zhuang K, Liu L, Su B, Yang R, Tien P, Zhang L, Gui X, Chen Z. Prevalence of drug-resistant HIV-1 in rural areas of Hubei province in the People's Republic of China. J Acquir Immune Defic Syndr. 2009 ;50:1-8;
7.Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease..J Neurochem. 2009;109 Suppl 1:153-9.
8.Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res. 2008;5 (6):525-32.
9.Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A. 2008;105(49):19318-23.
10.Greco SJ, Sarkar S, Johnston JM, Zhu X, Su B, Casadesus G, Ashford JW, Smith MA, Tezapsidis N. Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells. Biochem Biophys Res Commun. 2008 Nov 21;376(3):536-41.
11.Wang X, Su B, Fujioka H, Zhu X. Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am J Pathol. 2008 Aug;173(2):470-82.
12.Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008, 105 (6);2098-2108.
13.Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43 (12):1569-73.
14.Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep;64(17):2202-10.
15.Mei M, Su B, Harrison K, Chao M, Siedlak SL, Previll LA, Jackson L, Cai DX, Zhu X. Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease. J Neurochem. 2006 Dec; 99 (5):1377-88.
16.Li Liu, Bo Su, Ke Zhuang, Po Tien, Zhiwei Chen, and Linqi Zhang. Genetic characterization of full-length HIV type 1 genomes from 3 infected paid blood donors in Henan, China. J Acquir Immune Defic Syndr. 2005 Dec 1;40 (4):501-3.
17.Su B*, Liu L*, Wang F, Gui X, Zhao M, Tien P, Zhang L, Chen Z. HIV-1 subtype B' dictates the AIDS epidemic among paid blood donors in the Henan and Hubei provinces of China. AIDS. 2003; 17(17):2515-20. (*the first two authors contribute equally to this work)
苏擘
Email：bo_su@msn.com
工作及教育背景：
2010.2-至今山东大学医学院，副教授
2005.9-2010.1Case Western Reserve University, 病理系，博士后
2000.9-2005.7武汉大学生命科学学院，微生物专业，博士生
1996.9-2000.7 武汉大学生命科学学院，药学系，理学学士
奖励与荣誉：
2008 Case Western Reserve University, 医学院科学图片展 一等奖
2004.11武汉大学兰月亮奖学金
2004.1复旦大学谈家桢基金生命科学九源奖学金
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