【个人简介】 李晓燕教授，女，1963年出生，有机化学研究所博士生导师。

联系电话： **

E-mail： xli63@sdu.edu.cn
【学习及工作经历】 1979—1983 山东大学化学系，获理学学士学位。
1983—1986 山东大学化学系，获理学硕士学位；导师杨孔章教授；
研究方向，吸附与表面化学。
1986—1995 留校工作，先后任助教，讲师，副教授
1995—1999在德国DarmstadtUniversity of Technology 攻读博士学位，导师 Hans-Friedrich Klein教授；研究方向，金属有机化学；1999年10 月获理学博士学位。
1999—2002在德国Philipps-Universityof Marburg从事博士后研究，导师Joerg Sundermeyer 教授,研究方向：金属有机化学, 均相催化。
2002年起，山东大学化学与化工学院教授，有机化学专业 博士生指导教师。
【主讲课程】 有机化学，金属有机化学，金属有机化合物在有机合成中的应用。
【研究领域和兴趣】 研究方向：金属有机化学，催化化学，有机合成

1、C-H键的活化，M-H键的形成及其反应特性
C-H键的活化是金属有机化学中的“传统”而又充满活力的分支，它是许多有机合成反应和分子转化过程中的关键步骤。过渡金属配合物催化的C-H键的活化由于反应条件温和，选择性高，易于控制和实现，一直是金属有机化学家致力于探索的反应。由于在很多重要的化学过程，如氢甲酰化中的核心作用，使得[Co-H]结构单元的反应特性为化学家格外关注。三甲基膦作为高对称性，具有优良的光谱特征的分子，是十分适宜的辅助配体。利用强Lewis碱三甲基膦支持的Fe、Co和Ni化合物为原料，可实现一系列的C-H键的活化反应。我们研究小组目前主要致力于研究三甲基膦支持的金属有机氢化物的合成，表征及作为模型化合物在碳-碳偶联反应中的作用。

2、铁、钴和镍金属有机氢化物对不饱和键的催化还原作用

近年来随着实验技术的进步和人们对绿色化学的期待，过渡金属氢配合物的性质及其在催化反应中的应用越来越受到人们的广泛关注。在已知的过渡金属氢配合物催化体系中多以贵金属，如Rh、Ru、Pt和Pd等等，为中心原子。这些配合物不仅价格高，且多具有一定的毒性，使其工业化应用受到一定的限制。以Fe、Co和Ni为金属中心原子的氢配合物及催化应用的研究报道相对较少。我们研究小组目前主要致力于以Fe、Co和Ni的金属有机氢配合物的设计、合成及其对不饱和键的催化还原作用为研究内容，建立新的以Fe、Co和Ni为中心金属原子的催化体系。选择廉价铁、钴和镍氢化物作为催化剂进行催化研究，不仅对合成化学有重要意义，而且对绿色化学和可持续性发展有很好的推动作用。

3、C-F键的活化及其应用研究
C-F键的活化成为金属有机化学中的研究热点之一，且由于C-F键的高键能，使其成为一个艰难的挑战。开展C-F键活化研究不仅益于寻找新的氟化，脱氟及C-F键功能化途径；同时也对于催化氟降解有很重要的指导意义，在环境保护和绿色化学方面有很好的应用前景。
最近，我们利用三甲基膦支持的低价钴的配合物，通过环金属化反应，成功地实现了C-F键的活化，得到了第一个三价钴的金属有机氟化物。开拓了在该领域一个新的研究方向。我们将深入在该领域的研究工作，实现C-F键活化的同时，研究探索合成有机氟化合物的新方法。

【主要论著】代表性论文（SelectedPublications）：

1.Yuan, Shuo; Sun, Hongjian; Zhang, Shumiao; Li, Xiaoyan*, Synthesis offluorophenyl carbonyl cobalt(I) complexes and decarbonylation of2,4,5-trifluorobenzaldehyde catalyzed by CoMe(PMe₃)⁴,Inorganica Chimica Acta, 43, 100–105, 2016.
2.Wang, Lin; Sun, Hongjian; Li, Xiaoyan*, Imine Nitrogen BridgedBinuclear Nickel Complexes via N?H Bond Activation: Synthesis,Characterization, Unexpected C,N-Coupling Reaction, and Their CatalyticApplication in Hydrosilylation of Aldehydes, Organometallics, 34, 5175?5182, 2015.
3.Zhou, Hongwei; Sun, Hongjian; Zhang, Shumiao; Li, Xiaoyan*，Synthesis and Reactivity of a Hydrido CNC Pincer Cobalt(III) Complex andIts Application in Hydrosilylation of Aldehydes and Ketones, Organometallics, 34, 1479?1486, 2015.
4.Xue, Benjing; Sun, Hongjian; Li, Xiaoyan*, Syntheses and catalyticapplication of hydrido iron(II) complexes with [P,S]-chelating ligands inhydrosilylation of aldehydes and ketones, RSCAdv.,5, 52000-52006, 2015.
5.Zhang, Shumiao;, Li, Xiaoyan Li and Sun,Hongjian*, Selective aminationof aryl chlorides catalysed by Ni(PMe3)4, Dalton Trans., 44, 16224-16227,2015.
6.Zhao,Hua;Sun, Hongjian; Zhang, Shumiao; Li, Xiaoyan*，Synthesis and Characterization of Iron, Cobalt, and Nickel [PNP] PincerAmido Complexes by N–H Activation, Z. Anorg. Allg. Chem. 641, (14),2435–2439,2015.
7.赵华,孙宏建,王麟,李晓燕*,利用碳氢键活化合成钴的钳式配合物及其性质研究, 化 学 学 报, DOI:10.6023/A**,2015.
8.Peng, Zheng; Sun, Hongjian; Du, Aiqin; Li, Xiaoyan*，Introduction of (2-CF3)Phenyl Group via Nickel-catalyzed C–Cl BondActivation and Arylation, Z. Anorg. Allg.Chem., 641, (5), 838–84, 2015.
9.Huang, Shaofeng, Zhao, Hua, Li,Xiaoyan, Wang, Lin and Sun,Hongjian,*,Synthesis of [POCOP]-pincer iron and cobalt complexes via Csp3–Hactivation and catalytic application of iron hydride in hydrosilylationreactions, Rsc Adv., 5, 15660-15667, 2015.
10.Zhu, Gengyu, Wang, Lin, Sun,Hongjian, Li, Xiaoyan,* Formation of PCPpincer cobalt complexes with cobalt acyclopropane moieties via double Csp 3–Hbond activation, Rsc Adv., 5,19402-19408, 2015.
11.Niu,Qingfen; Zhang,Xiaohan; Zhang,Shumiao; Li, Xiaoyan and Sun,Hongjian*, Activation of vinylic carbon–chlorine bond by nickel complexessupported with phosphine ligands, Qingfen Niu, Inorg.Chim. Acta., 426, 165-170,2015.
12.Xu,Shilu, Li, Xiaoyan, Zhang Shumiao,Sun, Hongjian*, Synthesis andcharacterization of stable tripodal silyl ironand nickel Complexes, Inorg.Chim. Acta., 430, 161-167, 2015.
13.Guo, Yingmian, Zhang, Xiaohan,Wang, Lin, Sun, Hongjian and Li,Xiaoyan,*,Synthesis of Dinuclear Nickel Complexes fromDimethyltris(trimethylphosphine)nickel(II) via N–H Bond Activation, Z. Anorg.Allg. Chem., 641, 669-672, 2015.
14.Wang, Lin, Sun, Hongjian and Li,Xiaoyan,*Synthesis of Iron Hydridesvia Selective C-F/C-H Bond Activation in Fluoroaryl-imines and theirApplications in Catalytic Reduction Reactions, Eur.J. Inorg. Chem., 2732–2743, 2015.
15.Zhou, Hongwei, Sun, Hongjian,Zheng, Tingting, Zhang, Shumiao, Li,Xiaoyan*, Synthesis of Vinyl Nickel and Nickelacyclopropane ComplexesContaining a Chelate [P, Se]-ligand, Eur.J.Inorg. Chem., 3139–3145, 2015.
16.Zhao,Hua, Sun, Hongjian and Li,Xiaoyan*, SynthesisandCatalytic Property of Iron Pincer Complexes Generated byCsp3-H Activation,Organometallics 33,3535-3539,2014.
17.Zuo, Zhenyu, Sun,Hongjian, Wang,Lin and Li,Xiaoyan*, Hydrosilylationof Aldehydes and Ketones Catalyzed by Hydrido Iron Complexes Bearing ImineLigands, DaltonTrans., 43,11716-11722, 2014.
18.Sun,Yunqiang， Li，Xiaoyanand Sun, Hongjian*,[CNN]-pincernickel(II)complexes of N-heterocycliccarbene(NHC): synthesis and catalysis ofthe Kumada reaction of unactivated C–Cl bonds, DaltonTrans., 43, 9410, 2014.
19.Zhu,Gengyu, Li, Xiaoyan,Xu,Guoqiang, Wang, Linand Sun, Hongjian * Anew PC(sp3)P ligand and its coordination chemistry with low-valent iron, cobaltand nickel complexes, DaltonTrans.,,43,8595-8598, 2014.
20.Lu, Faguan ; Sun,Hongjian ;Du,Aiqin ; Feng, Lei and Li ,Xiaoyan*,Selective Alkylation and Arylation of C?F Bond with Grignard Reagents,Org.Lett.16,772?775, 2014.
21.Sun, Yunqiang ; Sun,Hongjian;Jia, Jiong ; Du, Aiqin andLi,Xiaoyan*,Transition-Metal-Free Synthesis of Fluorinated Arenes from PerfluorinatedArenes Coupled with Grignard Reagents, Organometallics,33,1079?1081, 2014.
22.Niu, Qingfen ; Sun,Hongjian;Wang, Lin; Hu,Qingping*and Li,Xiaoyan*,Reactivity of mer-hydrido(2-mercaptobenzoyl)tris(trimethylphosphine) cobalt(III)complex, DaltonTrans.,43, 4059–4066, 2014.
23.Li,Junye, Li, Xiaoyan, Wang,Lin,Hu,Qingping*aand Sun, Hongjian *,C–Cl bond activation and catalytichydrodechlorination of hexachlorobenzene by cobalt and nickel complexes withsodium formate as a reducing agent, DaltonTrans.,43, 6660-6666, 2014.
24 Li, Jingjing ; Zhang,Dongju*;Sun, Hongjian and Li, Xiaoyan*,Computationalrationalization of the selective C–H and C–F activations of fluoroaromaticimines and ketones by cobalt complexes, Org. Biomol. Chem.,12,1897–1907, 2014.
25.Wu, Siquan; Li, Xiaoyan; Xiong,Zichang;Xu, Wengang; Lu, Yunqiang; andSun Hongjian*, Synthesis and Reactivity of Silyl Iron, Cobalt, and NickelComplexes Bearing a [PSiP]-Pincer Ligand via Si?H Bond Activation，Organometallics， 32,3227-3237, 2013.
26.Xu, Wengwng; Sun, Hongjian;Xiong, Zichang; LiXiaoyan*,Acid-PromotedSelective Carbon?Fluorine Bond Activation and Functionalization of Hexafluoropropeneby Nickel Complexes Supported with Phosphine Ligands, Organometallics,32,7122-7132, 2013.
27.Li, Junye ; Zheng,Tingting ;Sun,Hongjian ; Xu,Wengang and Li,Xiaoyan*, Selective C–F/C–H bond activation of fluoroarenes bycobalt complex supported with phosphine ligands, DaltonTrans.,42,5740–5748, 2013.
28.Li, Junye ; Zheng,Tingting ;Sun,Hongjian and Li,Xiaoyan*,Selectively catalytic hydrodefluorination of perfluoroarenes by Co(PMe₃)₄with sodium formate as reducing agent and mechanism study, DaltonTrans.,42,13048–13053, 2013.
29.Niu, Qingfen ; Sun, Hongjian; Li , Xiaoyan* ; Klein, H.-F. ;Floerke,Ulrich,Synthesis and CatalyticApplication in Hydrosilylation of the Complex mer-Hydrido(2-mercaptobenzoyl)tris(trimethylphosphine)cobalt(III),Organometallics,32,5235?5238,2013.
30.Xu, Xiaofeng; Jia, Jiong;Sun,Hongjian; Liu,Yuxia; Xu,Wengang; Shi,Yujie;Zhang, Dongju*; Li, Xiaoyan*,Selective Activation of C-F and C-H Bondswith Iron Complexes, the Relevant Mechanism Study by DFT Calculations and Studyon the Chemical Properties of Hydrido Iron Complex, Dalton Trans., 42,3417-3428, 2013.
31.Liu, Nazhen; Zhu, Gengyu; Sun, Hongjian; Li, Xiaoyan*,Simple synthesisand structure characterization of a phosphonio methylidyne tantalum(V) complex,Inorg.Chem. Commun., 27,36-39, 2013.
32.Zhang, Zehua; Sun, Hongjian; Xu,Wengang; Li, Xiaoyan*, N-H bondactivation of 2-aminobenzophenone by trimethylphosphine complexes of nickel andcobalt, Polyhedron, 50,571-575. 2013.
33.Niu, Qingfen; Lu,Yunqiang; Sun, Hongjian; Li, Xiaoyan1*; Tao,Xutang2*,Novel phenyl-oligothiophene derivatives containing acetylenic spacersfor thin filmmaterials: synthesis, photophysicaland morphologyproperties,Dyesand pigment, 97，184-197, 2013.
34.Yang, Xiuxiu; Sun, Hongjian; Zhang,Shumiao; Li, Xiaoyan*,Nickel-catalyzed C-F bond activation and alkylation of polyfluoroaryl imines,J.Organomet.Chem.,, 723, 36-42, 2013.
35.Zheng, Tingting; Sun, Hongjian; Lu,Faguan; Harms, Klaus; Li, Xiaoyan*,Cobalt induced C-H Bond Activation and C8-Arylation of Caffeine with ArylBromides, Inorg.Chem.Commun.,30, 139-142,2013.
36.Niu, Qingfen;Lu,Yunqiang; Sun,Hongjian; Li, Xiaoyan1*; Tao,Xutang2*,Novel planar and star-shaped molecules: synthesis, electrochemical andphoto physical properties, Spectrochimica Acta Part A: Molecular and BiomolecularSpectroscopy, 377-385, 2013.
37.Niu, Qingfen; Xu,Xiaofeng; Sun,Hongjian; Li,Xiaoyan*, Synthesis of 2-Mercapto benzaldehyde,2-Mercaptocyclohex-1-enecarboxaldehydesand 3-Mercaptoacrylaldehydes,Chin. J.Chem., 30, 2495-2500, 2012.
38.Xu, Xiaofeng; Sun,Hongjian; Shi,Yujie; Jia,Jiong*,Li,Xiaoyan*,Imine-assisted C-F bond activation byelectron-rich iron complexes supportedby trimethylphosphine, DaltonTrans., 40,7866-7872, 2011.
39.Wang, Chenggen; Sun,Hongjian; Hu,Qingping;Li, Xiaoyan*,Carbonylative Formationof N-Acetyl-2,6-difluorobenzamidethrough N-H BondActivation of 2,6-Difluorobenzamidewith Ni(II) Complex Supported with PhosphineLigands, J.Organomet.Chem., 696,2815-2819, 2011.
40.Liu, Nazhen; Li, Xiaoyan; Sun, Hongjian*, Synthesis and properties ofnovel ortho-metallated cobalt(I) and iron(II) complexes through Csp2-H bond activationof dibenzylphenylphosphine,J.Organomet. Chem.,696,2537-2542, 2011.
41.Lian, Zhe; Xu, Xiaofeng; Sun, Hongjian; Chen, Yue; Zheng, Tingting;Li, Xiaoyan*，Imine-a ssisted C-F bond activation using low-valentcobalt compounds supported by trimethylphosphine ligands and formation of novelorganicfluorides，Dalton Trans., 39,9523-9529, 2010.
42.Zheng, Tingting; Sun, Hongjian;Ding, Jun; Zhang, Yanfeng; Li,Xiaoyan*, Effect of anchoring group and valent of cobalt center on thecompetitive cleavage of C-F bond activation, J.Organomet.Chem.,695, 1873-1877, 2010.
43.Zheng,Tingting; Li, Min; Sun, Hongjian; Harms, Klaus; Li, Xiaoyan*,Synthesis of new thiophenolato hydrido iron(II) complexes and theirsubstitution reactions with alkynes.Polyhedron,28(17), 3823-3827, 2009.
44.Xu, Guoqiang; Sun, Hongjian; Li, Xiaoyan*, Activation of sp3 Carbon-HydrogenBonds by Cobalt and Iron Complexes and Subsequent C-C Bond Formation.Organometallics,28(20),6090-6095, 2009.
45.Zheng,Tingting; Sun,Hongjian; Chen, Yue; Li, Xiaoyan*; Durr, Simon;Radius, Udo; Harms,Klaus, Synergistic Effect of a Low-Valent Cobalt Complex anda Trimethylphosphine Ligand on Selective C-F Bond Activation of Perfluorinated Toluene.Organometallics,28(19),5771-5776, 2009.
46.Wang,Aichen;Sun, Hongjian; Li, Xiaoyan*, Simple Synthesis of (Triphenylphosphoniomethylidene)(pentamethylcyclopentadienyl)titanium(II)Dichloride and Its Unexpected Reduction To Form a Trinuclear TitaniumCluster,Organometallics,28(17),5285-5288, 2009.
47.Cao, Ruixia ;Sun, Hongjian ;Li, Xiaoyan*, Facile Synthesis ofBis(isoindolinone) through Carbonylative Cyclization and Dimerization of Phenyliminewith Nickel(0) Complexes, Organometallics,27(8),1944-1947, 2008.
48.Chen,Yue; Sun, Hongjian; F.,Ulrich;Li, Xiaoyan*, Cyclometalation ReactionsInvolving C-Cl Bond Activation of ortho-Chlorinated Substrates withImine as AnchoringGroups by Cobalt Complexes,Organometallics,27,270-275, 2008.
49.Wang, Qibao;Sun, Hongjian;Fang,Shimin; Liu, Mingcui;Harms, Klaus; Li,Xiaoyan*, An Extension of the WittigReaction:Attack of Phosphorus Ylides at Acyl Groups in Organocobalt Complexes, Organometallics,26,6805-6811,2007.
50.Li, Xiaoyan*, Wang, Aichen ; Sun,Hongjian; Wang,Liang ;S.,Schmidt; Harms,Klaus ; Sundermeyer, J., Effect of Different Bases and Phosphorus Ylide on theSelective Deprotonation of Phosphorus Ylide Adduct Cp*TaCl4(CH2=PPh3),Organometallics,26,3456-3460,2007.
51.Li, Xiaoyan*, Wang, Aichen ;Wang,Liang ;Sun,Hongjian; Harms, Klaus ;Sundermeyer, J., Phosphorus Ylideas Precursor for the Formation of newHigh-valent Tantalum Phosphonio Methylidyne Complexes, Organometallics,26, 1411-1413,2007.
52.She, Lei; Li, Xiaoyan* ;Sun,Hongjian; Ding, Jun ;F.,Markus ;Klein,H.-F., Insertion of Alkynes into Ni-H Bonds: Synthesis of Novel VinylNickel(II)and Dinuclear Vinyl Nickel(II) Complexes containing a[P, S]-ligand,Organometallics, 26,566-570, 2007.
53.Jiao, Guili; Li, Xiaoyan* ;Sun, Hongjian; Xu,Xiaofeng, Synthesis and Reactivity of a novel Hydrido cobalt(III) ComplexContainingTrimethylphosphineandThiophenolatoLigands, J. Organomet. Chem., 692,4251–4258, 2007.
54.She, Lei; Sun, Hongjian; Li,Xiaoyan*, Reaction of the Acyl(hydrido) cobalt(III)Complex with 2-Propyn-1-ol, Z. Anorg. Allg.Chem. 633,2310-2313,2007.
55.Cao, Ruixia; Li, Xiaoyan*;and Sun,Hongjian *, Synthesis and Propertiesof Nickel(II) Complexes ContainingTrimethylphosphine and Thiophenolato-Ligands,Z.Anorg. Allg. Chem. 633, 2305-2309, 2007.
56.Li,Xiaoyan* ;Yu, Fengli; Sun,Hongjian; Huang, Liye; Hou, Haoqing,Reactions of Trimethylphosphine supported Cobalt Complexes with Salicylaldimines--Formationand Structures of Cobalt Compounds containing Salicylaldiminato [N:O]Ligands, Eur.J.Inorg.Chem.,4362-4367, 2006.
57.Li,Xiaoyan* ;Yu, Fengli; Sun, Hongjian, Hou,Haoqing, Novel stable five-coordinatediorgano cobalt(III) complexes: Formation, structure,and reaction with carbonmonoxide, Inorg.Chim. Acta,359,3117-3122, 2006.
58.Yu, Fengli; Li, Xiaoyan*;Sun, Hongjian,Unexpected Formation of a p-Coordinate Schiff Base cobalt(0) Complex, Z.Anorg.Allg. Chem.,632,501-504, 2006.
59.Li, Xiaoyan*; Sun, Hongjian; Yu, Fengli; Ulrich Fl?rke, andHans-Friedrich Klein, C-F Bond cleavage and Unexpected C-CN Activation byCobalt Compounds Supported with Phosphine Ligands, Organometallics,2006,25,4695-4697,2006.
60.Li, Xiaoyan* ; Markus Schopf, Ju¨rgen Stephan, Jennifer Kipke, KlausHarms, and Jo¨rgSundermeyer, Formation of η2-Ketene Rhenium(VII) Complexthrough the C,C- Coupling Reaction of Phosphonio Methylidyne Complexes withCarbonMonoxide,Organometallics,25,528-530, 2006.
61.Li,Xiaoyan ; Sun, Hongjian;*Ulrich Fl?rke, and Hans-Friedrich Klein,a，b-Unsaturated Carbonyl Compounds as Hard/Soft Chelating Ligands in MethylNickel Phenolates and the Structure of trans-Methyl-2-(3-phenyl-2,3-2-propenoyl)phenolatobis(trimethylphosphine)nickel(II),Organometallics,24,4347-4350,2005.
62.Li, Xiaoyan* ;Sun, Hongjian; Harms,K.; Sundermeyer,J., SimpleSynthesis and Structure Characterization of a Stable Niobium(V) Phosphonio methylidyne Complex,Organometallics,24,4699-4701,2005.
62.Li,Xiaoyan* ; M. Schopf, J. Stephan, J. Kippe, K. Harms, J. Sundermeyer,Simple Synthesis of an Allenylidene Heptavalent Rhenium(d0) Complex,, J.Am.Chem. Soc.126,8660-8661, 2004.
63.Li,Xiaoyan* ; Stephan, J.; Harms,K.;Sundermeyer,J.,Formation of aRhenium(VII) Phosphonio-Methylidyne Complex,Organometallics,23,3359-3361,2004.

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【科研项目】

2014.01--2017.12 国家自然科学基金项目"铁、钴和镍金属有机氢化物的合成及其对不饱和键的催化还原作用"（No.**）

2012.01--2015.12 国家自然科学基金项目"过渡金属配合物参与的C-F键功能化研究"（No.**）

2011.01--2013.12 山东省科技攻关项目“分子导体模型化合物--长链共轭体系铁、钴、镍金属有机配合物的合成及光电性能研究” （No.2011GGX10203）

2010.01--2012.12 国家自然科学基金项目"富电性铁、钴和镍的配合物对C-H键的活化作用及其应用探索研究"（No.**）

2008.01--2010.12 国家自然科学基金项目"新型金属有机氟化物的合成及其应用探索研究"（No.**）

2007.01--2009.12 山东省自然科学基金项目“新型含氟金属化合物的合成及其应用探索”

2006.01--2008.12 国家自然科学基金项目“高价态过渡金属卡拜化合物的合成及反应性能（No.**）

2006.01--2007.12 教育部博士点基金项目“高价态钒，铌和钽膦基卡拜化合物的合成”

2005.01--2006.12 科技部973项目“多层次三维碳纳米结构的组装和功能化修饰的研究”

2004.01--2005.12 教育部优秀青年教师基金项目“高价态过渡金属膦基卡拜化合物的合成”


【科研成果】 已发表学术论文140余篇及1项专利。
【所获专利】 Vanadium-imidoaryl-Komplexe fuer dieOlefinpolymerisation, DE-PatentNr.**.8 Arndt-Rosenau, M. Hoch,J.Sundermeyer, J. Kipke, X. Li


【联合培养情况】
【拟招收研究生情况】 每年计划招收2名硕士研究生，1-2名博士研究生。