【个人简介】 姓名: 王瑶

出生年月: 1984年10月

学历： 博士研究生

职称: 教授（博士生导师）

单位: 有机化学研究所

研究方向: 有机合成方法学研究、天然产物全合成以及其结构导向的化学生物学研究

地址: 山东省济南市山大南路27号新化学楼404

电话: **

Email: yaowang@sdu.edu.cn


【学习及工作经历】 教育经历：2002.9-2006.6 兰州大学 化学与化工学院 化学国家基地班 学士

2006.9-2012.6 兰州大学 功能有机分子化学国家重点实验室 有机化学 博士

工作经历：

2011.1-2012.12 兰州大学 优博计划选拔留任功能有机分子化学国家重点实验室

2013.1-2015.8 德国马普分子生理学研究所 洪堡学者

2015.9- 山东大学 化学与化工学院 教授
【主讲课程】
【研究领域和兴趣】 （1）不对称催化新概念/策略的设计、发展和应用

a. 不对称超分子过渡金属催化

b. 不对称超分子有机催化

c. 新的活化模式的探索和研究

（2）具有重要生理活性天然产物全合成及其结构导向的化学生物学研究


【主要论著】 1. Yao Wang, Hong Lu, Peng-Fei Xu*, Asymmetric Catalytic Cascade Reactions for Constructing Diverse

Scaffolds and Complex Molecules.

Acc. Chem. Res. 2015, 48, 1832-1844.

2. Yao Wang, Peng-Fei Xu, “Application of Oganocatalytic Cascade Reactions in Natural Products Synthesis and Drug Discovery”in: Catalytic Cascade Reactions.

Wiley-VCH, 2014.

3. Yun Gu^#, Yao Wang^#, Yong-Min Liang and Peng-Fei Xu*, Rationally Designed Multifunctional Supramolecular Iminium Catalysis: the Direct Vinylogous Michael Addition with Unmodified Linear Dienol Substrates.

Angew. Chem. Int. Ed. 2014, 53, 14128–14131. (Highlighted by Synfacts )

(^#: Co-first author.).

4. Yao Wang, Jonathan O. Bauer, Carsten Strohmann and Kamal Kumar*, A Bioinspired Catalytic Oxygenase Cascade to Generate Complex Oxindoles.

Angew. Chem. Int. Ed. 2014, 53, 7514–7518.

5. Yong-Long Zhao, Yao Wang, Jian Cao, Yong-Ming Liang, and Peng-Fei Xu*, Organocatalytic Asymmetric Michael–Michael Cascade for the Construction of Highly Functionalized N-Fused Piperidinoindoline Derivatives.

Org. Lett. 2014, 16, 2438-2441.

6. Tian-Yang Yu, Yao Wang, Xiu-Qin Hu and Peng-Fei Xu*, Triphenylphosphine Oxide-Catalyzed Stereoselective Poly- and Dibromination of Unsaturated Compounds.

Chem. Commun. 2014, 50, 7817-7820.

7. Tian-Yang Yu^#, Yao Wang^#, and Peng-Fei Xu*, An Unusual Triphenylphosphine Oxide Catalyzed Stereoselective 1,3-Dichlorination of Unsaturated Ketoesters.

Chem.-Eur. J. 2014, 20, 98–101.

(^#:Co-first author).

8. Hong-Bo Zhang, Yao Wang, Yun Gu and Peng-Fei Xu*, Lewis- and Br?nsted-Acid Cooperative Catalytic Radical Coupling of Aldehydes and Azodicarboxylate.

RSC Adv. 2014, 4, 27796-27799.

9. Dan-Dan Tang, Yao Wang, Jun-Ru Wang and Peng-Fei Xu*, Phosphine-Mediated Synthesis of Trifluoromethyl Substituted Pyrroles Using TFAA as the CF₃ Source.

Tetrahedron Lett. 2014, 30, 4133–4135.
10. Yong-Long Zhao^#, Yao Wang^#, Xiu-Qin Hu, and Peng-Fei Xu*, Merging organocatalysis with transition metal catalysis and using O₂ as the oxidant for enantioselective C–H functionalization of aldehydes.

Chem. Commun. 2013, 49, 7555-7557.

^(#:Co-first author).

11. Yao Wang, Tian-Yang Yu, Hong-Bo Zhang, Yong-Chun Luo, and Peng-Fei Xu*, Hydrogen-Bond-Mediated Supramolecular Iminium Ion Catalysis.

Angew. Chem. Int. Ed. 2012, 51, 12339–12342.

(Highlighted by Synfacts and Chin. J. Org. Chem.)

12. Yao Wang, Yong-Chun Luo, Hong-Bo Zhang, and Peng-Fei Xu*, Concise Construction of the Tetracyclic Core of Lycorine-Type Alkaloids and the Formal Synthesis of ?-Lycorane Based on Asymmetric Bifunctional Thiourea-Catalyzed Cascade Reaction.

Org. Biomol. Chem. 2012, 10, 8211–8215.

13. Cheng-Yong Jin, Yao Wang, Yao-Zong Liu, Chao Shen, and Peng-Fei Xu*, Organocatalytic Asymmetric Michael Addition of Oxindoles to Nitroolefins for the Synthesis of 2, 2-Disubstituted Oxindoles Bearing Adjacent Quaternary and Tertiary Stereocenters.

J. Org. Chem. 2012, 77, 11307–11312.

14. Zhen-Xin Jia, Yong-Chun Luo, Yao Wang, Liang Chen, Peng-Fei Xu*, and Binghe Wang, Organocatalytic aza-Michael-Michael Cascade Reactions: A Flexible Approach to Synthesize 2,3,4-Trisubstituted Tetrahydroquinolines.

Chem.-Eur. J. 2012, 18, 12958–12961.

15. Yao Wang, Yong-Chun Luo, Xiu-Qin Hu, and Peng-Fei Xu*, A Powerful Cascade Approach for Expeditious Synthesis of Trifluoromethylated Furans.

Org. Lett. 2011, 13, 5346–5349. (Highlighted by Synfacts)

16. De-Feng Yu, Yao Wang, and Peng-Fei Xu*, Diastereo- and Enantioselective Synthesis of a Novel Tetracyclic Ring System via an Organocatalytic One-Pot Reaction.

Adv. Synth. Catal. 2011, 353, 2960–2965.

17. De-Feng Yu, Yao Wang, and Peng-Fei Xu*, Oganocatalytic Enantioselective Multicomponent Cascade Reaction: Facile Access to Tetrahydropyridines with C3 All-Carbon Quaternary Stereocenters.

Tetrahedron 2011, 67, 3273–3277.

18. Yao Wang, De-Feng Yu, Yao-Zong Liu, Hao Wei, Yong-Chun Luo, Darren J. Dixon, and Peng-Fei Xu*, Multiple-Organocatalyst-Promoted Cascade Reaction: A Fast and Efficient Entry into Fully Substituted Piperidines.

Chem.-Eur. J. 2010, 16, 3922–3925.

19. Yong-Chun Luo, Huan-Huan Zhang, Yao Wang, and Peng-Fei Xu*, Synthesis of ?-Amino Acids Based on Chiral Tricycloiminolactone Derived from Natural (+)-Camphor.

Acc. Chem. Res. 2010, 43, 1317–1330.

20. Hao Wei, Yao Wang, Bing Yue, and Peng-Fei Xu*, Synthesis of Substituted 1,2-Dihydropyridines from Propargyl Vinyl Ethers and Allenic Vinyl Ethers by Gold-Catalyzed Claisen Rearrangement and 6π-Aza-electrocyclization.

Adv. Synth. Catal. 2010, 352, 2450–2454.

21. Yao Wang, Rong-Gang Han, Yong-Long Zhao, Shu Yang, Peng-Fei Xu*, and Darren J. Dixon*, Asymmetric Organocatalytic Relay Cascades: Catalyst-Controlled Stereoisomer Selection in the Synthesis of Functionalized Cyclohexanes.

Angew. Chem. Int. Ed. 2009, 48, 9834–9838.

(Highlighted by Synfacts and Chin. J. Org. Chem.)

22. Rong-Gang Han, Yao Wang, Yu-Ye Li, and Peng-Fei Xu*, Proline-Mediated Enantioselective Construction of Tetrahydropyridines via a Cascade Mannich /Intramolecular Cyclization Reaction.

Adv. Synth. Catal. 2008, 350, 1474–1478.


【科研项目】 国家自然科学基金(青年基金) 在研、主持

“齐鲁青年学者”特聘教授科研启动经费 在研、主持


【科研成果】 甘肃省科技进步一等奖 2014

洪堡科研奖学金 2013

甘肃省自然科学一等奖 2010

"The Excellent Poster Award" of the 11^th Tetrahedron Symposium 2010

宝钢奖学金 2010




【所获专利】 许鹏飞，王瑶，胡秀琴, 一种合成含三氟甲基呋喃化合物的方法.Granted No.: CN ** B.


【联合培养情况】
【拟招收研究生情况】 欢迎对有机化学和化学生物学感兴趣的本科生、硕士生、博士生和博士后加入本课题组。