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山东师范大学生命科学学院导师教师师资介绍简介-张鸿雁(校内)

本站小编 Free考研考试/2020-12-01


张鸿雁教授


简介:
张鸿雁,女,汉族,博士,1978年2月,山东莱芜。


教育经历:
2004/09-2007/09 天津科技大学,食品工程与生物技术学院,博士,食品科学。
2001/09-2004/07 齐鲁工业大学,生物工程学院,硕士,发酵工程。
1996/09-2000/07 齐鲁工业大学,生物工程学院,本科,发酵工程。
工作经历:
2018/02-至今 山东师范大学 生命科学学院食品科学系任教,职位:教授。
2017/11-2018/11 加拿大英属哥伦比亚大学(UBC) 职位:访问****。
2011/12-2018/02 山东师范大学 生命科学学院食品科学系任教,职位:副教授。
2009/11-2014/10 山东师范大学 化学化工与材料科学学院,职位:博士后。
2007/09-2011/12 山东师范大学 生命科学学院食品科学系任教,职位:讲师。
研究兴趣,领域:
研究方向:
1、食品安全快速检测方法研究:主要针对食品中的农兽药残留、雌激素干扰物类危害物等建立试纸条快速检测方法、光热传感器快速检测方法等。
2、潜在新型食品安全危害物的筛查、鉴定及风险评价:主要建立雌激素干扰物的非定向筛查方法,并将其用于食品加工过程中产生的潜在新型雌激素干扰物的筛查鉴定;建立纳米微塑料的定性定量检测方法,并将其用于食品中纳米微塑料残留的检测。
3、饮食因素对癌症转移的影响机理研究;循环肿瘤细胞在体捕获方法用于癌症早期诊断的研究等。
开设课程:
本科:食品安全学、食品化学、食品安全管理与控制、食品安全风险分析
主持或参加科研项目及人才计划项目情况:
1、国家自然基金面上项目,**,乳制品加工中产生的潜在新型雌激素干扰物的非定向筛查与鉴定,2019/01-2022/12,60万元,在研,主持。
2、国家重点研发计划子课题,2016YFD**,跨境食品潜在、新发有害物及其代谢物多元识别技术研究与数据库构建子课题,2016/07-2020/12,98.28万元,在研,主持。
3、山东省自然科学基金面上项目,ZR2016CM47,基于免疫磁珠及石墨烯光热效应的沙门氏菌快速、灵敏检测方法研究,2017/01-2019/02,13万元,已结题,主持。
4、国家自然科学基金青年项目,**,环境雌激素对单细胞内雌激素受体作用的原位、动态、定量研究,2012/01-2014/12,25万元,已结题,主持。
5、国家博士后科学基金项目,,己烯雌酚对单细胞内雌激素受体作用的原位、动态、定量研究,2011/01-2014/10,3万元,已结题,主持。
6、国家自然科学基金仪器专项,**,适用于单细胞内活性小分子物质检测的荧光分析仪,2013/01-2016/12,320万元,在研,参与。
7、国家自然科学基金,**,微流控芯片同时检测单细胞内多种自由基的研究,2012/01-2014/12,30万元,已结题,参与。
8、国家自然科学基金,**,活细胞内分子事件过程示踪的荧光成像探针的探索性研究,2011/01-2014/12,280万元,已结题,参与。
9、国家自然科学基金,**,环境中痕量雌酮分子印迹吸附检测的基础研究,2006/01-2008/12,29万元,已结题,参与。
代表性论文:
[1] Wang ML, Wang Q, Li XQ, Lu LX, Du SY, Zhang HY*, Selection and Identification of Diethylstilbestrol-Specific Aptamers Based on Magnetic-bead SELEX. Microchemical Journal, 2020, DOI: 10.1016/j.microc.2020.105354.
[2] Zhang JH, Zang LG, Wang T, Wang XW, Jia M, Zhang D and Zhang HY*, A solid-phase extraction method for estrogenic disrupting compounds based on the estrogen response element. Food Chemistry, 2020, 333:127529.
[3] Wang Y, Su SP, Du SY, Gao Y, Xu ZX and Zhang HY*, Rapid detection for Salmonella typhimurium by conventional resistive temperature sensor based on photothermal effect of carboxylated graphene oxide. Food Analytical Methods, 2020, 13:1755-1763.
[4] Jia M, Pang SX, Liu XY, Mao YF, Wu CC and Zhang HY*, Effect of dietary phytochemicals on the progression of breast cancer metastasis based on the in vivo detection of circulating tumor cells. Journal of Functional Foods, 2020, 65: 103752.
[5] Liu MY, Zhang SQ, Du SY, Pang SX, Liu XY and Zhang HY*, A high throughput screening method of endocrine disrupting chemicals in tap water and milk samples based on estrogen receptor α and gold nanoparticles. Analytical Methods, 2020, 12: 200-204.
[6] Lu LX, Wang ML, Zhang D and Zhang HY*, Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence. Analyst, 2019, 144:6647-6652.
[7] Du SY, Wang Y, Liu ZC, Xu ZX* and Zhang HY*, A portable immune-thermometer assay based on the photothermal effect of graphene oxides for the rapid detection of Salmonella typhimurium. Biosensors and Bioelectronics, 2019, 144:111670.
[8] Jia M, Mao YF, Wu CC, Wang S* and Zhang HY*, A platform for primary tumor origin identification of circulating tumor cells via antibody cocktail-based in vivo capture and specific aptamer-based multicolor fluorescence imaging strategy. Analytica Chimica Acta, 2019, 1082: 136-145.
[9] Jia M, Liu ZC, Wu CC, Zhang Z, Ma LY, Mao YF, Lu XN and Zhang HY*, Detection of Escherichia coli O157:H7 and Salmonella enterica serotype Typhimurium based on cell elongation induced by beta-lactam antibiotics. Analyst, 2019, 144: 4505-4512.
[10] Jia M, Liu JJ, Zhang JH and Zhang HY*, An immunofiltration strip method based on the photothermal effect of gold nanoparticles for the detection of Escherichia coli O157:H7. Analyst, 2019, 144: 573-578.
[11] Zhang D, Du SY, Su SP, Wang Y, Zhang HY *, Rapid detection method and portable device based on the photothermal effect of gold nanoparticles, Biosensors and Bioelectronics, 2019, 123:19-24.
[12] Jia M, Li SM, Zang LG, Lu XN, Zhang HY*, Analysis of biomolecules based on the surface enhanced raman spectroscopy. Nanomaterials, 2018, 8(9): 730-757.
[13] Zhang Z, Wang Q, Han LY, Du SY, Yu HF, Zhang HY*, Rapid and sensitive detection of Salmonella typhimurium based on the photothermal effect of magnetic nanomaterials. Sensors and Actuators B: Chemical, 2018, 268: 188-194.
[14] Zhang W, Wang JY, Li P*, Wu CC, Zhang HY, Zhang W, Wang H and Tang B*, Transferrin-navigation Nano Artificial Antibody Fluorescence Recognition of Circulating Tumor Cells. Scientific Reports, 2017, 7: 10142.
[15] Wu CC, Liu ZC, Zhang Z, Jiang YH, Zhang HY*, The effect of selected food phytochemicals on breast cancer metastasis based on in vivo capture of circulating tumor cells, Food & Function, 2017, 8: 2698-2701.
[16] Xiao L, Zhang Z, Wu CC, Han LY, Zhang HY*. Molecularly imprinted polymer grafted paper-based method for the detection of 17β-estradiol. Food Chemistry, 2017, 221: 82-86.
[17] Zhang HY, Zhang Z, Wang YH, Wu CC, Li QL, Tang B. Rapid and sensitive detection of cancer cells based on the photothermal effect of graphene functionalized magnetic microbeads, ACS Applied Materials & Interfaces, 2016, 10: 29933-29938.
[18] Zhou JH, Zheng YP, Liu JJ, Bing X, Hua JJ, Zhang HY*, A paper-based detection method of cancer cells using the photo-thermal effect of nanocomposite, Journal of Pharmaceutical and Biomedical Analysis, 2016, 117: 333-337.
[19] Zhang HY, Jia ZZ, Wu CC, Zang LG, Yang GW, Chen ZZ, Tang B, In vivo capture of circulating tumor cells based on transfusion with a vein indwelling needle, ACS Applied Materials & Interfaces, 2015, 7: 20477-20484.
[20] Zhang HY, Wang YH, Li QL, Zhang FM, Tang B, A size amplified immune magnetic microbeads strategy in the rapid detection of circulating tumor cells, Chemical Communications, 2014, 50: 7024-7027.
[21] Zhang HY, Wang MM, Wang Y, Li QL, Zhou JH, Huo F, Tang B, Preparation and application of an immunoaffinity column based on an antibody with strong affinity and packing material with good stability, Food Additives & Contaminants: Part A, 2013, 30(5): 853-860.
[22] Zhu D, Zhang HY*, Bing X, Preparation of an immunoaf?nity column for the clean-up of fermented food samples contaminated with citrinin, Food Additives & Contaminants: Part A, 2013, 30: 389-394.
[23] Zhang HY, Fang GZ, Wang S. Applications and recent developments of multi-analyte simultaneous analysis by enzyme-linked immunosorbent assays, Journal of Immunological Methods, 2011, 368: 1-23.
[24] Zhang HY, Wang S, Review on enzyme-linked immunosorbent assays for sulfonamide residues in edible animal products, Journal of Immunological Methods, 2009, 350: 1-13.
[25] Zhang HY, Zhang Y, Wang S, Zang LG, Validation and comparative studies of four sulfonamide immunoassays based on the same generic polyclonal antibody, Applied Biochemistry and Biotechnology, 2009, 158(3): 642-652.
[26] Zhang HY,Zhang Y, Wang S, Development of flow-through and dip-stick immunoassays for screening of sulfonamide residues, Journal of Immunological Methods, 2008, 337: 1-6.
[27] Zhang HY, Wang L, Zhang Y, Fang GZ, Zheng WJ, Wang S, Development of an enzyme-linked immunosorbent assay for seven sulfonamide residues and investigation of matrix effects from different food samples, Journal of Agricultural and Food Chemistry, 2007, 55: 2079-2084.
[28] Zhang HY, Duan ZJ, Wang L, Zhang Y, Wang S, Hapten synthesis and development of polyclonal antibody-based multi-sulfonamide immunoassays, Journal of Agricultural and Food Chemistry, 2006, 54: 4499-4505.
[29] Wang S, Zhang HY, Wang L, Duan ZJ, Kennedy I, Analysis of sulfonamide residues in edible animal products, Food Additives & Contaminants, 2006, 23(4): 362-384.
授权的发明专利
[1] 张鸿雁,杜淑媛,刘兆臣,苏树朋,王莹。一种集检测载体与信号产生于一体的温度计快速检测方法,中国发明专利,申请日2018.07.04,授权公告日2020.05.05,授权公告号:CN B,专利号 ZL 2018 1 **.8。
[2] 张鸿雁,刘兆臣,杜淑媛。一种基于细菌增长对细菌快速镜检的方法,中国发明专利,申请日2017.08.29,授权公告日2019.05.28,授权公告号:CN B,专利号ZL 2017 1 **.6。
[3] 张鸿雁,张震,罗钰。一种基于免疫磁性纳米材料光热效应的鼠伤寒沙门氏菌快速检测方法,中国发明专利,申请日2017.08.29,授权公告日2019.05.28,授权公告号:CN B,专利号ZL 2017 1 **.7。
[4] 张鸿雁,肖蕾,刘兆臣,张震。用于检测17?-雌二醇的分子印迹聚合物试纸条及其制备方法,中国发明专利,申请日2016.09.06,授权公告日2019.03.19,授权公告号:CN B,专利号ZL 2016 1 **.8。
[5] 张鸿雁,郑艳苹,刘静静,周建华。一种基于纳米材料光热效应的细胞检测方法及其装置,中国发明专利,申请日2015.01.29,授权公告日2017.07.21,授权公告号:CN B,专利号ZL 2015 1 **.1。
[6] 张鸿雁,王言红,唐波. 用于外周血中循环肿瘤细胞捕获的免疫磁性微球, 中国发明专利,申请日2014.4.17,授权公告日2017.01.11,授权公告号:CN B,专利号ZL 2014 1 **.X。
主编或参编书籍:
[1]《食品安全风险分析理论与应用》,张鸿雁主编,2019年,科学出版社;
[2]《Food Chemical Hazard Detection, Development and application of new technologies》, “Recent developments in liquid chromatography-mass spectrometry for the detection of food chemical hazards”, Shuo Wang, 2014, WILEY Blackwell.
[3]《酶联免疫吸附分析方法(基本原理及其在食品化学污染物检测中的应用)》,王硕主编,2010年,科学出版社;
[4]《食品安全学》,王硕主编,2016年,科学出版社;
[5]《食品安全检测技术》,王硕主编,2016年,化学工业出版社。
指导学生获奖:
指导2020届研究生王明录获评2019年山东省研究生优秀成果奖三等奖。
指导2017届研究生张震毕业论文获评2018年山东省优秀硕士学位论文。
第九届山东省大学生科技节“龙大杯”食品加工与安全创新设计大赛优秀奖;二等奖。
指导本科生获第十三届“挑战杯”山东省大学生课外学术科技作品竞赛一等奖。
指导2015届研究生王言红毕业论文获评2016年山东省优秀硕士学位论文。



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