姓 名
张大同
性 别
男
出生年月
1973.04

学 历
博士
毕业时间
2006.06
专 业
药物化学、有机化学

电 话
**
邮 编
250353
E-MAIL
datong_zhang@163.com

单 位
化学与制药工程学院
通讯地址
济南市长清区大学路3501号 齐鲁工业大学化工学院

个人简历：
1991.9-1995.7，山东医科大学 药学专业 本科；
1995.9-1998.7，山东医科大学 药物化学专业 硕士；
2003.09-2006.7，山东大学 有机化学专业 博士；
2006.7至今，齐鲁工业大学化学与制药工程学院任教。制药工程与药物制剂系教授，硕士研究生导师。
2012.7-2013.1，美国Virginia Commonwealth University 访问****

研究领域：
药物化学、有机分子荧光探针。

奖励和荣誉：

2007年指导的论文被评为“校级优秀本科毕业论文”
2008年指导的论文被评为“校级优秀本科毕业论文”
2009年指导的论文被评为“校级优秀本科毕业论文”
2012年指导的论文被评为“校级优秀本科毕业论文”

2008年指导的论文被评为2009年“山东省优秀学士学位论文”
2011年被评为山东轻工业学院优秀教师.
2014年 “有机废弃物发酵和可燃气体输送发电监控关键技术研究”获山东省科技进步二等奖(第三名)


发表文章：
1. Xiao-Bo Wang, Xue Hao, DatongZhang*,Yan Jiang.Reaction-based Fluorescent Turn-on Probe for Selective Detection of Thiophenols in Aqueous Solution and Living Cell. Dyes and Pigments, 2017, 142, 167-174.
2. Xiao-Bo Wang, Datong Zhang*.A novel reaction-based fluorescent turn-on probe for biothiols and its application in cell imaging. Sensors and Actuators B: Chemical, 241 (2017) 327–334.
3. Xiao-Bo Wang, Jianhua Zhou, Datong Zhang*and Bin Wang. A very fast 3-hydroxy-coumarin-based fluorescent probe for highly selective and sensitive detection of thiophenols and its application in water samples. Anal. Methods, 2016, 8, 6916–6922.
4. Ruibing An, Peng Wei, Datong Zhang*,Na Su.A highly selective 7-hydroxy-3-methyl-benzoxazinone based fluorescent probe for instant detection of thiophenols in environmental samples. Tetrahedron Letters, 2016, 57, 3039-3042.
5.Ruibing An, Datong Zhang,*, Yan Chen, Yue-zhi Cui.A“turn-on”?uorescentandcolorimetricsensor forselectivedetection ofCu2+ in aqueous media and living cells.Sensors and Actuators B: Chemical, 222 (2016) 48–54.
6. Peng Wei, Datong Zhang*, Zhigang Gao, Wenqing Cai, Weiren Xu, Lida Tang, GuilongZhao*.Iodine Monochloride(ICl) as a Highly Efficient, GreenOxidant for the Oxidation of Alcohols to CorrespondingCarbonyl Compounds.Synthetic Commun.,2015,45(12):1457-1470.
7. Datong Zhang*, Yuntong Ma, Ruibing An. New colorimetric chemosensor based on rhodamine hydrazide to detect Cu2+ ions by naked eye.Res Chem Intermed., 2015, 41(8): 5059-5069.
8. Gao Zhigang, Zhang Datong*, Wei Peng, Wang Zhe, Xie Yafei, Liu Yuqiang, Xu Weiren, Tang Lida, Zhao Guilong*. A facile convergent synthetic procedure for 3-deoxydapagliflozin as SGLT2 inhibitor. Chin. J. Org. Chem, 2014, 34, 1829-1939..
9. Datong Zhang, Yuntong Ma, Yu Liu and Zhao-Peng Liu. Synthesis of sulfonylhydrazone- and acylhydrazone- substituted 8-ethoxy-3-nitro-2H-chromenes as potent antiproliferative and apoptosis inducing agents. Arch. Pharm. Life Sci. 2014, 347, 576-588.
10. Datong Zhang*, Lingyan Huo, Laichun Lu, Qiong Yu, Jianwu Wang, Yanyan Yang. Synthesis and preliminary antibacterial evaluation of hydroxamic acid and N-formyl hydroxylamine derivatives bearing oxazole ring. Medicinal Chemistry Research, 2013, 22(3):1426-1437.
11. Datong Zhang*,Guangtian Wang, Guilong Zhao,Weiren Xu, Lingyan Huo. Synthesis andCytotoxic Activity of Novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives. European Journal of Medicinal Chemistry, 2011,46 (12):5868-5877.
12.Datong Zhang*, Guangtian Wang, Chubing Tan*, Weiren Xu, Yuan Pei and Lingyan Huo. Synthesis and biological evaluation of 3-(1H-indol-3-yl)pyrazole-5-carboxylic acid derivatives. Archives of Pharmacal research, 2011, 34(3):343-355.
13.Datong Zhang*, Jiong Jia, Lijuan Meng, Weiren Xu, Lida Tang, and Jianwu Wang. Synthesis and Preliminary Antibacterial Evaluation of 2-Butyl Succinate-based Hydroxamate Derivatives Containing Isoxazole Rings.Archives of Pharmacal research, 2010, 33(6):831-842.
14. Datong Zhang, Zongheng Wang, Weiren Xu, Fanggang Sun, and Jianwu Wang. Design,Synthesis and Antibacterial Activity of Novel Actinonin Derivatives Containing Benzimidazole Heterocycles. European Journal of Medicinal Chemistry, 2009,44 (5)，2202-2210

目前承担和参与项目：
先后主持和参与了山东省自然科学基金、山东省中青年科学家奖励基金和济南市高校院所自主创新计划，并承担多项企事业单位横向课题。


社会兼职：中国化学会会员。现为Bioorganic& medicinal chemistry letter、European journal of medicinal chemistry、Journal of heterocyclic chemistry, Medicinal Chemistry Research等期刊审稿专家。