【基本信息】
姓名：牛庆芬
职称：副教授/硕士研究生导师
单位：齐鲁工业大学化学与制药工程学院，山东省分子工程重点实验室522
地址：济南市长清区大学路3501号
邮箱：niujing1216@126.com
【研究方向】
1、有机合成化学及有机合成新方法
2、高效有机光伏材料的设计、合成及性能研究
3、新型高性能分子荧光探针的构建，包括可见光、近红外和双光子荧光探针的设计合成及应用研究
4、生物医学成像研究，包括活细胞、活组织及动物活体荧光成像研究
【教育工作背景】
2014年，齐鲁工业大学，副教授
2013年，山东大学，有机化学，博士
2008年，山东师范大学，化学，学士
【教研科研项目】
1. 校级研究生教育优质课程建设项目《合成化学》，2018，主持
2. 校级教研项目《化学化工“大类招生、分类培养”模式的实践与探索》，2015，主持
3. 山东省自然科学基金-- A-π-D-π-A型有机光伏给体材料的设计、合成及其性能研究，2017，主持
4. 山东省教改项目，2019，主持
【代表性学术论文】（发表SCI论文55余篇，被引频次1021次，H指数为22）
2019年
1. Zongrang Guo, Tingting Hu, Xingjian Wang, Tao Sun, Tianduo Li,* Qingfen Niu*, Highly sensitive and selective fluorescent sensor for visual detection of Cu²⁺in water and food samples based on oligothiophene derivative, Journal of Photochemistry and Photobiology A: Chemistry37 (2019) 50-58.
2. Yang Li, Qingfen Niu*, Tao Wei, Tianduo Li*, Novel thiophene-based colorimetric and fluorescent turn-on sensor for highly sensitive and selective simultaneous detection of Al³⁺and Zn²⁺in water and food samples and its application in bioimaging, Analytica Chimica Acta1049 (2019) 196-212.
3. Zongrang Guo, Tingting Hu, Tao Sun, Tianduo Li*, Hong Chi, Qingfen Niu*, A colorimetric and fluorometric oligothiophene-indenedione-based sensor for rapid and highly sensitive detection of cyanide in real samples and bioimaging in living cells, Dyes and Pigments 163 (2019) 667–674.

4. Zongrang Guo, Qingfen Niu*, Tianduo Li, Tao Sun, Hong Chi, A fast, highly selective and sensitive colorimetric and fluorescent sensor for Cu²⁺and its application in real water and food samples, Spectrochimica Acta Part A：Molecular and biomolecular spectroscopy 213 (2019) 97–103.

5. Zongrang Guo,Qingfen Niu*, Qingxin Yang, Tianduo Li, Hong Chi, A highly selective and sensitive dual-mode sensor for colorimetric and turn-on fluorescent detection of cyanidein water, agro-products and living cells, Analytica Chimica Acta1065 (2019) 113-123.
6. Junjie Wang, Tao Wei, Feng Ma, Tianduo Li*,Qingfen Niu*, A novel fluorescent and colorimetric dual-channel sensor for the fast, reversible and simultaneous detection of Fe³⁺and Cu²⁺based on terthiophene derivative with high sensitivity and selectivity, Journal of Photochemistry and Photobiology A: Chemistry383 (2019)111982.
7. Zhenyu Zuo*, Xiaomei Song, Dongyan Guo, Zongrang Guo, Qingfen Niu*, A dual responsive colorimetric/fluorescent turn-on sensor for highly selective, sensitive and fast detection of Fe³⁺ions and its applications, Journal of Photochemistry and Photobiology A: Chemistry382 (2019)111876.
8. Zongrang Guo, Qingfen Niu*,Tianduo Li, Enhua Wang, Highly chemoselective colorimetric/fluorometric dual-channel sensor with fastresponse and good reversibility for the selective and sensitive detection of Cu²⁺,Tetrahedron 75 (2019) 3982–3992.
9. Junjie Wang, Qingfen Niu*, Tingting Hu, Tianduo Li, Tao Wei, A new phenothiazine-based sensor for highly selective, ultrafast, ratiometric fluorescence and colorimetric sensing of Hg²⁺: Applications to bioimaging in living cells and test strips, Journal of Photochemistry and Photobiology A: Chemistry384 (2019)112036.
10. Chunpeng Li, Qingfen Niu*, Shanshan Zhang, Tianduo Li, Qingxin Yang, Synthesis, photophysical and electrochemical properties of a new star-shaped molecule with a 1,3,5-triethynylbenzene core and diketopyrrolopyrrole arms, RSC Advances 9 (2019) 28357–28363.
11. Pengcheng Yin,Qingfen Niu*, Qingxin Yang, Linxin Lan, Tianduo Li, A new “naked-eye” colorimetricand ratiometric fluorescentsensor forimaging Hg²⁺inliving cells, Tetrahedron, 75 (2019) 130687.
12. Pengcheng Yin, Qingfen Niu,* Tao Wei, Tianduo Li,Yang Li, Qingxin Yang, A new thiophene-based dual functional chemosensor for ultrasensitive colorimetricdetection ofCu²⁺in aqueous solution and highly selective fluorimetricdetection of Al³⁺in living cells, Journal of Photochemistry and Photobiology A: Chemistry 2019, in press.
2018年
1. Tao Sun, Qingfen Niu*, Yang Li, Tianduo Li, Tingting Hu, Enhua Wang, Haixia Liu, A novel oligothiophene-based colorimetric and fluorescent “turn on” sensor for highly selective and sensitive detection of cyanide in aqueous media and its practical applications in water and food samples, Sensors and Actuators B: Chemical258(2018) 64-71.2. Qingfen Niu*, Linxin Lan, Tianduo Li, Zongrang Guo, Tao Jiang, Zhiyi Zhao, Zhenshuai Feng, Jinying Xi, A highly selective turn-on fluorescent and naked-eye colorimetric sensor for cyanide detection in food samples and its application in imaging of living cells,Sensors and Actuators B: Chemical276(2018) 13-22.3. Qingfen Niu*, Tao Sun, Tianduo Li*, Zongrang Guo, He Pang, Aggregation induced emission characteristics for multiple targets of copper, zinc and cyanide ions sensing and its practical application in water and food samples, Sensors and Actuators B: Chemical266(2018) 730-743.4. Tao Sun¹, Yang Li¹, Qingfen Niu*, Tianduo Li, Yan Liu, Highly selective and sensitive determination of Cu²⁺ in drink and water samples based on a 1,8-diaminonaphthalene derived fluorescent sensor, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy195(2018) 142-147.5. Chuantao Gu, Deyu Liu, Junyi Wang, Qingfen Niu*, Chunyang Gu, Bilal Shahid, Bing Yu, Hailin Cong*, Renqiang Yang*, Alkylthienyl substituted asymmetric 2D BDT and DTBT-based polymer solar cells with a power conversion efficiency of 9.2%, J. Mater. Chem. A 6 (2018) 2371.6. Zongrang Guo, Qingfen Niu*, Tianduo Li, Highly sensitive oligothiophene-phenylamine-based dual-functional fluorescence “turn-on” sensor for rapid and simultaneous detection of Al³⁺and Fe³⁺in environment and food samples, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy200(2018) 76-84.7. Linxin Lan, Qingfen Niu*, Tianduo Li, A highly selective colorimetric and ratiometric fluorescent probe for instantaneous sensing of Hg²⁺in water, soil and seafood and its application on test strips, Analytica Chimica Acta 1023 (2018) 105-114.
8. Linxin Lan, Tianduo Li, Tao Wei, He Pang, Tao Sun, Enhua Wang, Haixia Liu, Qingfen Niu*, Oligothiophene-based colorimetric and ratiometric fluorescence dual-channel cyanide chemosensor: Sensing ability, TD-DFT calculations and its application as an efficient solid state sensor, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 193 (2018) 289–296.
9. Shanshan Zhang, Tao Sun, Dejun Xiao, Fang Yuan, Tianduo Li, Enhua Wang, Haixia Liu, Qingfen Niu*, A dual-responsive colorimetric and fluorescent chemosensor based on diketopyrrolopyrrole derivative for naked-eye detection of Fe³⁺and its practical application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 189 (2018) 594–600.
10. Tao Sun, Qingfen Niu*, Tianduo Li, Zongrang Guo, Haixia Liu, A simple, reversible, colorimetric and water-soluble fluorescent chemosensor for the naked-eye detection of Cu²⁺in ~ 100% aqueous media and application to real samples, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 188 (2018) 411–417.

2017年
1. Shanshan Zhang, Qingfen Niu*, Linxin Lan, Tianduo Li*, Novel oligothiophene-phenylamine based Schiff base as a fluorescent chemosensor for the dual-channel detection of Hg²⁺and Cu²⁺ with high sensitivity and selectivity, Sensors and Actuators B: Chemical240(2017) 793-800.2. Linxin Lan,Qingfen Niu*, Zongrang Guo, Haixia Liu, Tianduo Li*, Highly sensitive and fast responsive “turn-on” fluorescent sensor for selectively sensing Fe³⁺and Hg²⁺in aqueous media based on an oligothiophene derivative and its application in real water samples, Sensors and Actuators B: Chemical244(2017) 500-508.3. Tao Sun, Qingfen Niu*, Yang Li, Tianduo Li*, Haixia Liu, Novel oligothiophene-based dual-mode chemosensor: “Naked-Eye” colorimetric recognition of Hg²⁺and sequential off-on fluorescence detection of Fe³⁺and Hg²⁺in aqueous media and its application in practical samples, Sensors and Actuators B: Chemical248(2017) 24-34.
4. Shanshan Zhang, Qingfen Niu*, Tao Sun, Yang Li, Tianduo Li, Haixia Liu, The synthesis and properties of linear A–π–D–π–A type organic small molecule containing diketopyrrolopyrrole terminal units, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 183 (2017) 172–176.
5. Shanshan Zhang, Xingxing Wu, Qingfen Niu*, Zongrang Guo, Tianduo Li, Haixia Liu, Highly Selective and Sensitive Colorimetric and Fluorescent Chemosensor for Rapid Detection of Ag⁺, Cu²⁺and Hg²⁺ Based on a Simple Schiff Base, Journal of Fluorescence27 (2017) 729–737.
6. Tao Sun,Qingfen Niu*, Zongrang Guo, Tianduo Li, A simple highly sensitive and selective turn-on fluorescent chemosensor for the recognition of Pb²⁺, Tetrahedron Letters 58 (2017) 252-256.
7. Shanshan Zhang, Tao Sun, Zhen Xu, Tianduo Li, Yang Li, Qingfen Niu*, Haixia Liu, Novel biphenylene-diketopyrrolopyrrole-based A-π-D-π-A molecule: Synthesis, optical, electrochemical and electronical properties, Tetrahedron Letters 58 (2017) 2779-2783.
2016年1. Xingxing Wu, Qingfen Niu*, Tianduo Li, Novel one-pot synthesis of symmetrically substituted ureas, Synthetic Communications 46 (2016).2. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Xiaoyan Li, Highly selective, sensitive and fast-responsive fluorescent sensor for Hg²⁺, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 163 (2016) 45–48.
3. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Qiuchen Su, A Phenylamine-Oligothiophene-Based Fluorescent Chemosensor for Selective Detection of Hg(II), Journal of Fluorescence26 (2016) 1053–1058.
4. Xingxing Wu, Qingfen Niu*, Tianduo Li*, A novel urea-based “turn-on” fluorescent sensor for detection of Fe³⁺/F^?ions with high selectivity and sensitivity, Sensors and Actuators B: Chemical222(2016) 714-720.5. Xingxing Wu, Qingfen Niu*, Tianduo Li, Yuezhi Cui, Shanshan Zhang, A highly sensitive, selective and turn-off fluorescent sensor based on phenylamine-oligothiophene derivative for rapid detection of Hg²⁺, Journal of Luminescence 175 (2016) 182–186.
6. Qingfen Niu, Shumiao Zhang, Xiaoyan Li, Hongjian Sun*, Olaf Fuhr, Dieter Fenske, Synthesis and Characterization of Diorganocobalt Chlorides by Aliphatic Vinylic C–Cl Bond Activation, Zeitschrift für anorganische und allgemeine Chemie642 (2016) 866-869.7. Qingfen Niu*, Xingxing Wu, Shanshan Zhang, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A highly selective and sensitive fluorescent sensor for the rapid detection of Hg²⁺ based on phenylamine-oligothiophene derivative, Spectrochimica Acta Part A Molecular and biomolecular spectroscopy 153 (2016) 143-146.
8. Xingxing Wu, Shanshan Zhang,Qingfen Niu*, Tianduo Li*, A novel urea-derived fluorescent sensor for highly selective and sensitive detection of Fe³⁺, Tetrahedron Letters 57 (2016) 3407-3411.
9. Qiuchen Su,Qingfen Niu*, Tao Sun, Tianduo Li, A simple fluorescence turn-on chemosensor based on Schiff-base for Hg²⁺-selective detection, Tetrahedron Letters 57 (2016) 4297-4301.
2015年1. Shanshan Zhang, Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A Fast-Responsive Fluorescent Sensor for Hg²⁺with High Selectivity and Sensitivity in Aqueous Media, Journal of Fluorescence25 (2015) 1543–1548.
2. Qingfen Niu,Xiaohan Zhang, Shumiao Zhang, Xiaoyan Li, Hongjian Sun*, Activation of vinylic carbon-chlorine bond by nickel complexes supported with phosphine ligands, Inorganica Chimica Acta 426 (2015) 165-170.
2014-2012年

1.Qingfen Niu,Hongjian Sun, Lin Wang, Qingping Hu*,Xiaoyan Li*, Reactivity of mer-hydrido(2-mercaptobenzoyl)-tris(trimethylphosphine)cobalt( III ) complex, Dalton Trans. 43 (2014) 4059?4066.

2.Qingfen Niu, Hongjian Sun, Xiaoyan Li*, Synthesis, photophysical and thin-film self-assembly properties of novel fluorescent molecules with carbon–carbon triple bonds, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 133 (2014) 229–240.

3. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Xutang Tao*, Novel phenyl-oligothiophene derivatives containing acetylenic spacers for thin film materials: Synthesis, photophysical and morphology properties, Dyes and Pigments 97 (2013) 184?197.

4. Qingfen Niu, Hongjian Sun, Xiaoyan Li*, H.-F. Klein, Ulrich Flo?rke, Synthesis and Catalytic Application in Hydrosilylation of the Complex mer-Hydrido(2-mercaptobenzoyl)tris-(trimethylphosphine)cobalt(III), Organometallics 32 (2013) 5235?5238.

5. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Novel planar and star-shaped molecules: Synthesis, electrochemical and photophysical properties, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 107 (2013) 377–385.

6. Qingfen Niu, Xiaofeng Xu, Hongjian Sun, Xiaoyan Li*, Synthesis of 2-Mercaptobenzaldehyde, 2-Mercaptocyclohex-1-enecarboxaldehydes and 3-Mercaptoacrylaldehydes, Chin. J. Chem. 30 (2012) 2495–2500.
【学术兼职】
中国化学会会员；山东省化工协会会员；担任《Nanoscale》、《Current Organic Chemistry》、《Journal of Hazardous Materials》、《Sensors and Actuators B: Chemical》、《Analytical Chemistry》、《Analytica Chimica Acta》、《Analyst》、《Analytical Methods》、《Talanta》、《New Journal of Chemistry》、《Spectrochimica Acta Part A》、《Polymer Chemistry》、《RSC Advances》、《ACS Omega》、《ACS Sustainable Chemistry and Engineering》、《ACS Applied Materials& Interfaces》、《Dalton Transactions》、《Applied Organometallic Chemistry》、《Journal of Photochemistry and Photobiology A: Chemistry》、《Sensors》、《Food Chemistry》、《Inorganica Chimica Acta》、《Chemical Research in Toxicology》、《Small》、《Journal of the Chinese Chemical Society》等国际知名期刊的审稿专家。
【奖励与荣誉】
1. 山东省研究生优秀创新成果三等奖，共同指导教师，2019
2. 山东省优秀硕士学位论文2篇，共同指导教师，2019
3. 国家级研究生奖学金，共同指导教师，2019
4. 山东省省级教学成果二等奖，2018
5. 山东省研究生优秀科技创新成果三等奖，共同指导教师, 2018
6. 齐鲁工业大学研究生优秀硕士学位论文，共同指导教师，2018
7. 齐鲁工业大学研究生优秀创新成果二等奖，共同指导教师, 2018
8. 齐鲁工业大学研究生优秀创新成果一等奖，共同指导教师, 2017
9. 齐鲁工业大学研究生优秀创新成果三等奖，共同指导教师, 2017
10. 齐鲁工业大学大学生创新创业训练计划，指导教师, 2018
11. 国家级大学生创新创业训练计划，指导教师, 2019
12. 国家级大学生创新创业训练计划，指导教师, 2017
13. 国家级大学生创新创业训练计划，指导教师，2015
【教学经历】
1. 本科生课程：学术班《无机化学》、《无机化学实验》、《化学专业综合实验》及《毕业论文》
2. 硕士生课程：《现代有机合成化学》、《合成化学》
【研究生培养】
目前，培养研究生10名，已毕业研究生5名，其中1人考入中国科技大学攻读博士学位；1人进入山东中医药大学在编教师；1人从事高中教师职业；3人次获国家级研究生奖学金，多人获校级奖学金。