学历
博士

职称
副教授

所属部门
生物化学与分子生物学系

招生专业


联系方式
电话: -8444 E-mail: zhuchunyuan@sdau.edu.cn

个人简介

朱春原，女，博士，副教授。2009年毕业于中国海洋大学海洋药物教育部重点实验室药物化学专业，获医学博士学位，其间在美国佐治亚州立大学化学系学习一年。2009年至2011年于山东大学微生物技术国家重点实验室从事博士后研究，专业为结构生物学。2011年7月起在山东农业大学生命科学学院生物化学与分子生物学系任教，为生物化学与分子生物学国家级教学团队成员。

教学工作

承担本科生《分子生物学》、《生物化学实验》及研究生《现代分子生物学》课程的教学工作。

研究方向

重要蔬菜致病菌关键蛋白结构与功能研究

科研项目

1.国家自然科学基金青年基金《辣椒疫霉菌效应蛋白RxLR23晶体结构及转运机制研究》（No. **）
2. 山东省优秀中青年科学家科研奖励基金《辣椒疫霉菌效应蛋白RxLR12的晶体结构及转运机制研究》（No. BS2015SW009）
3. 中国博士后科学基金《硒代小分子衍生物在测定蛋白质结构中的应用研究》（No. ）
4. 山东省博士后创新项目专项资金《硒代小分子衍生物在解决相关蛋白质晶体结构相位问题中的应用研究》（No. ）

研究专利

谷立川，朱春原，许素娟，陈颖，李冰清，一种c-di-GMP 的分离纯化方法，2014. 3，中国，ZL 2011 1 **.X

发表论文

1. Chunyuan Zhu#, Xiaoyan Yang#, Rong Lv#, Zhuang Li, Xiaomeng Ding, Brett M. Tyler, Xiuguo Zhang. Phytophthora capsici homologue of the cell cycle regulator SDA1 is required for sporangial morphology, mycelial growth and plant infection. Molecular Plant Pathology, 2016, 17(3), 369-387.
2. Li Fu#, Chunyuan Zhu#, Xiaomeng Ding#, Xiaoyan Yang, Paul F. Morris, Brett M. Tyler, Xiuguo Zhang*. Characterization of cell-death-inducing members of the pectate lyase gene family in Phytophthora capsici and their contributions to infection of pepper, Molecular Plant-Microbe Interactions, 2015, 28, 7, 766-775.
3. Guijun Shang#, Deyu Zhu#, Ning Li#, Junbing Zhang#, Chunyuan Zhu, Defen Lu, Cuilan Liu, Qian Yu, Yanyu Zhao, Sujuan Xu, Lichuan Gu*. Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP, Nature Structural & Molecular Biology, 2012, 19(7), 725-727.
4. Chunyuan Zhu, Yan-Tuan Li*, Zhi-Yong Wu, Yu-Lan Song. Synthesis, crystal structure and antibacterial activity of a new binuclear copper(II) complex with N,N'-bis(N-hydroxyethylaminopropyl) oxamido as a bridging ligand, J. Coord. Chem., 2007, 60, 465-472
5. Chunyuan Zhu, Yan-Tuan Li*, Jian-Dong Wu, Zhi-Yong Wu, Xia Wu. Tris[(3-aminopropyl) dimethylammonium] decavanadate(V) hexahydrate, Acta Cryst. E63, 2007, m1777-m1778.
6. Chunyuan Zhu, Yan-Tuan Li*, Zhi-Yong Wu, Ning-Yu Xiao. Tris(N,N-dimethylethane-1,2-diammonium) decavanadate(V) pentahydrate, Acta Cryst. E63, 2007, m547-m549.
7. Chunyuan Zhu, Yan-Tuan Li*, Zhi-Yong Wu, Wei Sun. N,N’-Bis(2-ammonioethyl) oxamide diaquabis(oxalato-κ2O,O’)cuprate(II) dehydrate, Acta Cryst. E62, 2006, m3585-m3587.
8. Chunyuan Zhu, Yan-Tuan Li*, Zhi-Yong Wu, Man Jiang. Tris-(propane-1,3-diammonium) decavanadate 5.5-hydrate, Acta Cryst. E62, 2006, m3092-m3095.
9. Yan-Tuan Li*, Chunyuan Zhu, Zhi-Yong Wu, Man Jiang, Cui-Wei Yan. Synthesis, crystal structure, antibacterial activities and DNA-binding studies of a new μ-oxamido-bridged binuclear copper(II) complex, J. Coord. Chem., 2009, 62, 3795-3809.
10.Yan-Tuan Li*, Chunyuan Zhu, Zhi-Yong Wu, Man Jiang, Cui-Wei Yan. Synthesis, crystal structures and anticancer activities of two decavanadate compounds, Transition Met. Chem., 2010, 35, 597-603.
11.Yan-Tuan Li*, Chunyuan Zhu, Guo-Qiang Li, Cui-Wei Yan, Gui-Yun Xu. Synthesis and magnetism of copper(II)-lanthanide(III)-copper(II) heterotrinuclear complexes with N,N’-bis[2-(dimethylamino)ethyl] oxamidocopper(II), Transition Met. Chem., 2005, 30, 850-855.
12.Yan-Tuan Li*, Chunyuan Zhu, Cui-Wei Yan, Jian-Min Dou, Da-Qi Wang. Synthesis, characterization and magnetic studies of oxamido-bridged copper(II)-iron(III) heterobinuclear complexes, Polish J. Chem., 2005, 79, 1265-1273.
13.Shan Jin, Chunyuan Zhu, Minyong Li, Binghe Wang*. Identification of the first fluorescent α-amidoboronic acids that change fluorescent properties upon sugar binding, Bioorg. Med. Chem. Lett., 2009, 19, 1596-1599.
14.Shan Jin, Chunyuan Zhu, Yunfeng Cheng, Minyong Li, Binghe Wang*. Synthesis and carbohydrate binding studies of fluorescent α-amidoboronic acids and the corresponding bisboronic acids, Bioorg. Med. Chem., 2010, 18, 1449-1455.
15.Shan Jin, Minyong Li, Chunyuan Zhu, ViLinh Tran, Binghe Wang*. Computer-based de novo design, synthesis, and evaluation of boronic acid-based artificial receptors for selective recognition of dopamine, Chembiochem, 2008, 9, 1431-1438.