李莉，博士，中国科学院海洋研究所实验海洋生物学重点实验室研究员，青岛海洋科学与技术试点国家实验室研究员，国家贝类产业技术体系岗位科学家。1997年毕业于聊城大学生物系，2000年获南开大学动物学硕士学位，2003年获中国科学院海洋研究所海洋生物学博士学位，分别在美国新泽西州立大学(Rutgers University)和美国弗吉尼亚州立大学 (Virginia Commonwealth University) 完成博士论文和进行博士后研究。
l 研究领域
多年来致力于贝类资源的保护与可持续利用，围绕牡蛎等贝类的经济与生态服务功能，利用基因组学、遗传学与分子生物学手段，结合海洋生态学以及进化等多学科，开展牡蛎等贝类重要经济性状的遗传解析与分子育种以及适应进化与牡蛎资源保护等研究。
l 招生专业及方向
海洋生物，水产养殖
l 联系方式
研究室：实验海洋生物学重点实验室
山东省青岛市南海路7号，中国科学院海洋研究所实验海洋生物学重点实验室（6号楼3楼）。邮编：266071；E-mail: lili@qdio.ac.cn, 电话：0532-8289 6728
l 承担的主要科研项目
主要在研项目：贝类耐高温低氧与抗病性状的遗传关联机制(国家重点研发计划)，贝类环境胁迫疾性疾病防控（农业部），长牡蛎野生群体适应性分化及其机制（自然基金），服务于“美丽海洋”的生物调控技术与示范（中科院先导专项）等多项国家级与省部级课题。
l 研究成果及奖励
共发表SCI论文100余篇，其中近五年发表SCI论文65篇，第一或通讯作者SCI论文40余篇；授权发明专利15项；获贝类新品种授权1项、山东省自然科学奖1项。代表性成果发表在Nature（并列第一作者，IF：43.07，第4位），Nature Ecology & Evolution（IF：10.97，并列第一作者，第1位）, Cell Death & Disease(IF=5.965，并列通讯作者)和Molecular Ecology Resources（IF=7.049，并列通讯作者 ) 等国际期刊，代表性成果分别荣获2016年度和2018“海洋与湖沼十大科技进展”。近5年SCI论文他引1691次，单篇最高他引799次。
l 代表性论文及著作
10篇代表性论文(* 通迅作者；#作者贡献相同)
1）Li Li#, Ao Li#, Kai Song#, Jie Meng#, Ximing Guo#, Shiming Li#, Chunyan Li, Pierre De Wit, Huayong Que, Fucun Wu, Wei Wang, Haigang Qi, Fei Xu, Rihao Cong, Baoyu Huang, Yingxiang Li, Ting Wang, Xueying Tang, Sheng Liu, Busu Li, Ruihui Shi, Youli Liu, Chen Bu, Chi Zhang, Weiming He, Shancen Zhao, Hongjun Li, Shoudu Zhang, Linlin Zhang and Guofan Zhang？*. Divergence and plasticity shape adaptive potential of the Pacific oyster. Nature Ecology & Evolution, 2018. 2(11): p. 1751-1760.
2）Guofan Zhang#*, Xiaodong Fang#, Ximing Guo#*, Li Li#, Ruibang Luo#, Fei Xu#, Pengcheng Yang#, Linlin Zhang#, Xiaotong Wang#, Haigang Qi, Zhiqiang Xiong, Huayong Que, Yinlong Xie, Peter W. H. Holland, Jordi Paps, Yabin Zhu, Fucun Wu, Yuanxin Chen, Jiafeng Wang, Chunfang Peng, Jie Meng, Lan Yang, Jun Liu, Bo Wen, Na Zhang, Zhiyong Huang, Qihui Zhu, Yue Feng, Andrew Mount, Dennis Hedgecock, Zhe Xu, Yunjie Liu, Tomislav Domazet-Loso, Yishuai Du, Xiaoqing Sun, Shoudu Zhang, Binghang Liu, Peizhou Cheng, Xuanting Jiang, Juan Li, Dingding Fan, Wei Wang, Wenjing Fu, Tong Wang, Bo Wang, Jibiao Zhang, Zhiyu Peng, Yingxiang Li, Na Li, Jinpeng Wang, Maoshan Chen, Yan He, Fengji Tan, Xiaorui Song, Qiumei Zheng, Ronglian Huang, Hailong Yang, Xuedi Du, Li Chen, Mei Yang, Patrick M. Gaffney, Shan Wang, Longhai Luo, Zhicai She, Yao Ming, Wen Huang, Shu Zhang, Baoyu Huang, Yong Zhang, Tao Qu, Peixiang Ni, Guoying Miao, Junyi Wang, Qiang Wang, Christian E. W. Steinberg, Haiyan Wang, Ning Li, Lumin Qian, Guojie Zhang, Yingrui Li, Huanming Yang, Xiao Liu, Jian Wang, Ye Yin*, Jun Wang*. The oyster genome reveals stress adaptation and complexity of shell formation. Nature, 2012. 490(7418): p. 49-54.
3）Ao Li, Li Li*, Wei Wang and Guofan Zhang. Evolutionary trade-offs between baseline and plastic gene expression in two congeneric oyster species. Biology Letters, 2019. 15(6), **.
4）Xingyu Liu, Li Li*, Ao Li, et al. Transcriptome and Gene Coexpression Network Analyses of Two Wild Populations Provides Insight into the High-Salinity Adaptation Mechanisms of Crassostrea ariakensis. Marine Biotechnology (NY), 2019. doi:10.1007/s10126-019-09896-9.
5）Youli Liu, Li Li*, Baoyu Huang, Wei Wang and Guofan Zhang. RNAi based transcriptome suggests genes potentially regulated by HSF1 in the Pacific oyster Crassostrea gigas under thermal stress. BMC Genomics, 2019. 20(1): p. 639.
6）Jiafeng Wang, Haigang Qi, Li Li*, Huayong Que, Di Wang, Guofan Zhang*. Discovery and validation of genic single nucleotide polymorphisms in the Pacific oyster Crassostrea gigas. Molecular Ecology Resources, 2015. 15(1): p. 123-135.
7）Baoyu Huang, Linlin Zhang, Yishuai Du, Fei Xu, Li Li*, Guofan Zhang*. Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates. Scientific Reports, 2017. 7: p. 13.
8）Busu Li, Kai Song, Jie Meng, Li Li*, Guofan Zhang*. Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas. BMC Genomics, 2017. 18: p. 14.
9）Yingxiang Li, Linlin Zhang, Tao Qu, Xueying Tang, Li Li*, Guofan Zhang*. Conservation and divergence of mitochondrial apoptosis pathway in the Pacific oyster, Crassostrea gigas. Cell Death & Disease, 2017. 8: p. 13.
10）Zhicai She, Li Li*, Jie Meng, Zhen Jia, Huayong Que, Guofan Zhang*. Population resequencing reveals candidate genes associated with salinity adaptation of the Pacific oyster Crassostrea gigas. Scientific Reports, 2018. 8.