肖建
USER　ID: 100377
性　　别: 男
出生日期: 1981-06-03
工作单位:
职　　务: 无
研究方向:

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肖建，男，教授，硕士研究生导师。1981年6月生，山东昌乐人，中共党员。2005年硕士毕业于南开大学元素有机化学研究所，2009 年博士毕业于新加坡南洋理工大学化学与生物化学系，师从著名有机化学家Teck-PengLoh教授（南洋理工大学化学与生物化学系创建者，中国科技大学****学者，师从哈佛大学诺贝尔奖得主E.J.Corey教授），从事新型手性催化剂的设计、合成及不对称催化反应在药物合成中的研究。2009 年至2010 年在南洋理工大学从事博士后研究。2010年至2012年在中国科学院大连化学物理研究所任副研究员。2013年至2014年在美国加利福尼亚州世界顶尖研究所The Scripps Research Institute做高级访问研究, 师从著名生物学家和化学家、有机小分子催化和抗体药物领域的先驱Carlos F. Barbas III教授。2012年9月起为青岛农业大学化学与药学院教授，有机化学学科带头人，功能有机分子实验室负责人，不对称催化与有机合成团队负责人。迄今为止，肖建博士在AngewandteChemie International Edition、Organic Letters、Chemical Communications、Advanced Synthesis & Catalysis等国际一流杂志上发表SCI论文36篇，其中第一作者或通讯作者30篇，影响因子5.0以上13篇，总引用次数超过400次，其中单篇引用超过100次，多篇被国际著名评论杂志Synfacts收录并作为亮点介绍。现为美国化学会Organic Letters, ACS catalysis, Journal of Organic Chemistry和英国皇家化学会Chemical Communications,RSC Advance等杂志的特约审稿人并多次被约稿。2014年受邀请为Current Organic Chemsitry(IF:3.039)，Current Organocatalysis等杂志的特约编辑。受邀在南开大学，山东大学，中国石油大学等高校做报告。受邀在2014年第十届中美华人教授会议以及第五届全球科技催化大会等国际会议上做特邀报告。授权美国专利2项，主持和参与多项国家自然科学基金，海外基金，山东省中青年科学家奖励基金，青岛市青年科技专项以及青岛农业大学高层次人才启动基金等项目。热烈欢迎优秀的本科生报考本课题组研究生以及在本课题组进行科研工作！办公电话：**。邮箱：xj9698@163.com。Education and Academic Career2012-now Professor, Team LeaderQingdao Agricultural University2013-2014 Research Associate The Scripps Research Institute (Carlos F. Barbas III)2010-2012 Associate Professor Dalian Institute of Chemical Physics, CAS2009-2010 Research AssociateNanyang Technological University (Prof Teck-Peng Loh)2005-2009Ph.D Nanyang Technological University (Prof Teck-Peng Loh)2002-2005Master Nankai University (Prof Jin-Shan Li)1998-2002 BachelorQufu Normal UniversityHonors and Awards2004南开大学陈茹玉奖学金2010Best Poster Award, 8th Asian-European Symposium on Metal-Mediated Efficient Organic Synthesis(AES-MMEOS 2010)2012中国科学院大连化物所科技创新奖2013 山东省高校科研成果奖2015 Asian Core Program Lectureship Award（Singapore）2015 The Advisory Board，Merck IndexOnlineInvited Lectures2015年National University of Singapore（Singapore）2015年Nanyang Technological University（Singapore）2014年The 10th SINO-US Chemistry Professors Conference(Jinan）2014年The 5th Annual Global Congress of Catalysis 2014 (GCC-2014，Qingdao)2013年Shandong University,School of Pharmaceutical Sciences（Prof. Lei Liu）2013年China University of Petroleum, College of Science（Dr.Zhihua Peng）2012年Taizhou University,School of Pharmaceutical and Chemical Engineering（Prof. Qizhong Zhou）2011年 Qufu Normal University, School of Chemical Science and Chemical Engineering（Prof. Jinmao You）2011年Nankai University, College of Chemistry（Prof. Weidong Li）2010年University of Science and Technology of China, School of Chemistry and Materials Science（Prof. Guanwu Wang）Publications：35.Xu Lubin, Shao Zhuzhou, Wang Liang，Xiao Jian*, “Tandem sp3 C-H Activation/Decarboxylation of 2-Alkyl Azaarenes withCoumarin-3-Carboxylic Acid”, Org. Lett.2014, 16, 796. (IF = 6.36)34.Wang Liang, Xiao Jian*, “New Advancement of Cascade [1,5]-Hydrogen Transfer/Cyclization: A Method for Direct Functionalization of Inactive C(sp3)-H Bonds” 2014, Adv. Syn. Catal. 2014, 356, 1137. (IF = 5.66)33.Xiao Jian,*Chen Yuye, Zhu Shuai，Wang Liang, Xu Lubin, Wei Hongtao, “Diversified Construction of Chromeno[3,4-c]pyridin-5-one and Benzo[c]chromen-6-one Derivatives by Domino Reaction of 4-alkynyl-2-oxo-2H-chromene-3-carbaldehydes”, Adv. Syn. Catal.2014, 356, 1835. (IF = 5.66)32.Wang Liang,Xiao Jian*,LohTeck-Peng*, “Organocatalyticβ-Functionalization of Saturated Carbonyl Compounds---The State of the Art”, ChemCatChem, 2014, 6, 1183.(IF = 4.56)31.Shao Zhuzhou, Xu Lubin, Wang Liang,Wei Hongtao, Xiao Jian,* “Catalyst-free Tandem Michael Addition/Decarboxylation of (thio)coumarin-3-carboxylic Acids with Indoles: Facile Synthesis of Indole-3-substituted 3,4-dihydro(thio)coumarins”, Org. Biomol.Chem.2014, 12,2185. (IF = 3.56)30.Wang Liang,Chen Yuye, Xiao Jian*, “AlkylideneindoleniniumIons and Alkylideneindolenine: Key Intermediates for Asymmetric Synthesis of 3-Substituted Indoles”, Asian J.Org.Chem. 2014, 3，1036. (IF = 3.32)29.Xiao Jian *, Shao Zhuzhou, Xu Lubin, Wang Liang, “Catalyst-Free Three Component Reaction of 2-Methyl Azaarenes, Aromatic Aldehyes with 4-Hydroxyl-courmains for Facile Synthesis of Azaarene Functionalized Coumarin Derivatives via sp3 C-H Functionalization”2014, submitted. 28. Shao Zhuzhou, Wang Liang,Xu Lubin, Zhao Huaili and Xiao Jian *,“Facile Synthesis of Azaarene-2-substituted Chromanone Derivatives via Tandem sp3 C?H Functionlization/Decarboxylation of Azaarenes with 4-oxo-4H-chromene-3-carboxylic acid”RSC Advances2014,4, 53188. (IF = 3.84)27. Xu Lubin,Shao Zhuzhou,Wang Liang, Zhao Huaili and Xiao Jian *,” Catalyst-Free Synthesis of (Z)-2-Alkenylquinoline Derivatives via C(sp3)-H Functionalization of 2-Methylquinolines” Tetrahedron Lett.2014, 55， 6856. (IF = 2.38)26. Yu Xinzhang, Yu Songjie, Xiao Jian, Wan Boshun, Li Xingwei*, “Rhodium(III)-Catalyzed Azacycle-Directed Intermolecular Insertion of Arene C?H Bonds into α?Diazocarbonyl Compounds”, J. Org. Chem., 2013, 78, 5444.(IF = 4.72)25.Xiao Jian*, “Merging Organocatalysis with Transition Metal Catalysis: HighlyStereoselective Alkylation of Aldehydes”,Org. Lett.2012, 14, 1716. (IF = 6.36)0Highlighted by Synfacts 2012, 8, 0749.24.Xiao Jian*,“Oxidative Enamine Catalysis: Direct Catalytic Enantioselective β-Functionalization of Aldehydes”, ChemCatChem2012, 4, 612. (IF = 4.56)23.Liang Tao,Xiao Jian*, XiongZhiyi，Li Xingwei*, “Organocatalytic Asymmetric 1,4 Addition of Aldehydes to Acridiniums Catalyzed by a DiarylprolinolSilyl Ether”, J. Org. Chem.2012, 77, 3583. (IF = 4.72)22.NiuRui, Xiao Jian*, Liang Tao, Li Xingwei*, “Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-Oxindoles via Bronsted Acid-Catalyzed sp3C-H Functionalization”, Org. Lett.2012, 14, 676. (IF = 6.36)21.Xiao Jian, Zhao Kai, LohTeck-Peng*,“The OrganocatalyticEnantioselective Acid Free Alkylation of Aldehydes in Fluorinated Alcohols”,Chem. Comm. 2012, 48, 3548.(IF = 6.83)20.Huang Fen, XuLubin,Xiao Jian*, “OrganocatalyticEnantioselectiveDehydrogenative α-Alkylation of Aldehydes with Benzylic Compounds”, Chin. J. Chem.2012, 30, 2721. (InvitedSpecial Issue of "Asymmetric Synthesis", one of the most accessed papers from 11/2012 to 10/2013).19.NiuRui, Yang Shiying,Xiao Jian*, Liang Tao, Li Xingwei*, “Yb(OTf)3-Catalyzed Addition of 2-methylAzaarenesto Isatins via C-H Functionalization”, Chin. J. Catal.2012, 33, 1636. 18.Wang Xiaowei, Li Xuting, Xiao Jian, Jiang Yi, Li Xingwei*, “Rh(III)-Catalyzed Oxidative Olefination of N-(Naphthalen-1-yl)amides”, Synlett 2012, 1649. (IF = 2.42)17.Xiao Jian, Zhao Kai, LohTeck-Peng*,“Highly Enantioselective Intermolecular Alkylation of Aldehydes with Alcohols by Cooperative Catalysis of DiarylprolinolSilyl Ether with Br?nsted Acid”, Chem. Asian J. 2011, 6, 2890. (IF = 4.59)16.Xiao Jian and Li Xingwei*, “Gold ?-Oxo Carbenoids in Catalysis: Catalytic O-Atom Transfer to Alkynes”, Angew. Chem. Int. Ed. 2011, 50, 7226. (IF = 11.26)15.Xiao Jian, Lu, Yun-Peng, Liu, Yan-Ling, Wong, Poh-Shen, Loh, Teck-Peng*, “A New Class of Structurally Rigid Tricyclic Chiral Secondary Amine Organocatalyst: Highly EnantioselectiveOrganocatalytic Michael Addition of Aldehydes to Vinyl Sulfones”, Org. Lett.2011, 13, 876.(IF = 6.36)14.Xiao Jian, Xu, Feng-Xia, Lu,Yun-Peng, Liu, Yan-Ling, Loh, Teck-Peng*, “Highly Efficient and Modularly Tuned Bicyclic Organocatalyst for the Enantioselective Michael Addition of Aldehydes to Nitroalkenes”, Synthesis-Stuttgart, 2011, 1292. (IF = 2.69)13.XiaoJian,XuFeng-Xia, Lu Yun-Peng, LohTeck-Peng*, “Chemzymes: A New Class of Structurally Rigid Tricyclic Amphibian Organocatalyst Inspired by Natural Product”, Org. Lett.2010,12, 1220.(IF = 6.36)Highlighted by Synfacts 2011, 5, 0561.12.XiaoJian, Wong Zhen-Zhou, Lu Yun-Peng, LohTeck-Peng*, “Hexahydropyrrolo[2,3-b]indoles: A New Class of Structurally Rigid Tricyclic Skeleton for Oxazaborolidine-Catalyzed Asymmetric Borane Reduction”, Adv. Synth. Catal.2010, 352, 1107. (IF = 5.66)11.Xiao Jian and LohTeck-Peng*,“The OrganocatalyticEnantioselective Michael Addition of Aldehydes to Vinyl Sulfones in Water”, Synlett2010, 2029. (IF = 2.42)10.XiaoJianand LohTeck-Peng*, “Design, Synthesis and Optical Resolution of New Bifunctional Ligand: 1,1′-Dimethyl-octahydro-8,8′-Biquinoline-7,7′-diol”, Org. Lett.2009, 11, 2876. (IF = 6.36)9.XiaoJianand LohTeck-Peng*, “Unexpected Domino Ring Closure: Highly Stereoselective Construction of a Tetracyclic Indole Alkaloid Ring System”, Tetrahedron Lett. 2008, 49, 7184. (IF = 2.38)8.XiaoJianand LohTeck-Peng*, “Design and Synthesis of a Water-Tolerant Chiral Indium Complex: Application to One-Pot Three-Component Mannich-Type Reactions in Water”, Synlett 2007, 815. (IF = 2.42)7.LohTeck-Peng* andXiaoJian“Process for Preparation of Octahydrobiquinoline Compounds”, PCT International Patent Application, 2010, 59pp. Patent Number: WO **.LohTeck-Peng* andXiao Jian“Preparation of Tricyclic Chiral Compounds and Their Use in Asymmetric Catalysis”, PCT International Patent Application, 2010, 141pp. Patent number: WO**.XiaoJian, Lu Yong-Na, Wang Guo-Cang, Li Jin-Shan et al., “3-(3H-Inden-1-ylmethyl)-2,2'-bis(methoxymethoxy)1,1'-binaphthalenyl”ActaCrystallographica Section E 2005, 61, O1501. 4.Wang Guo-Cang, Xiao Jian, Lu Yong-Na, et al., “Synthesis, Crystal Structures and in Vitro Antitumor Activities of Some Arylantimony Derivatives of Analogues of Demethylcantharimide”, J. Organomet. Chem.2004, 689, 1631. (IF = 2.17)3.Wang Guo-Cang, Xiao Jian, Lu Yong-Na, et al., “Synthesis, Characterization and in Vitro Cytotoxicity Screening of Some Triarylbismuth(V) di(N-salicylidene) Amino Carboxylates and the Crystal Structure of (2-HOC6H4CH=NCH2CO2)2Bi(C6H5)3”, Appl. Organomet. Chem.2005, 19, 113. (IF = 2.25)2.Wang Guo-Cang, Lu Yong-Na, Xiao Jian, et al., “Synthesis, Crystal Structures and in Vitro Antitumor Activities of Some Organoantimony Arylhydroxamates”J. Organomet. Chem.2005, 690, 151. (IF = 2.17)1.GuoQun-Sheng, Lu Yong-Na, Liu Bing, Xiao Jian, Li Jin-Shan, “A Facile Synthesis of 3 or 3,3′-Substituted Binaphthols and Their Applications in the Asymmetric Addition of Diethylzinc to Aldehydes” , J. Organomet. Chem. 2006, 691, 1282. (IF = 2.17)