苏颖
博士，教授
邮箱：suying@ouc.edu.cn
电话：
地址：中国海洋大学鱼山校区达尔文馆219室
教育经历
1997.09-2001.07 清华大学，生物科学与技术系，学士
2001.09-2006.07 清华大学，生物科学与技术系，博士
工作经历
2006.10-2011.12 美国Cleveland Clinic, Lerner Research Institute, 博士后
2011.12-2014.09 美国Cleveland Clinic, Lerner Research Institute, Research Associate
2014.11-2015.12 美国布朗大学，Dept. MCB，Assistant Professor (Research)
2016.03-至今 中国海洋大学，海洋生命学院/海洋生物多样性与进化研究所，青年英才工程第一层次****
研究方向
动物胚胎发育过程中信号通路的转导机制及功能解析
利用斑马鱼和果蝇模式动物，针对 Hedgehog、Wnt、TGF?等重要信号通路，开展新调控因子的筛选、鉴定、及相关作用机制的研究，相应的研究结果已在Cell、Science、Science Signaling、Development Cell、eLife、Cell Communication and Signaling等发育生物学领域的国际知名学术期刊上发表。
目前主要在研方向包括：
1）血细胞发育及谱系发生的调控机理；
2）蛋白质翻译后修饰在发育信号转导途径中的功能解析；
3）诱导细胞死亡的JNK信号通路的新调控因子的鉴定及相关机制研究。

代表性学术成果
*通讯作者/^#共同一作
1. Chi C., Wang L., Lan W., Zhao L., Su Y.* (2018) PpV, acting via the JNK pathway, represses apoptosis during normal development of Drosophilawing. Apoptosisdoi: 10.1007/s10495-018-1479-2.
2. Zhao L., Wang L., Chi C., Lan W.,Su Y.*(2017) The emerging roles of phosphatases in Hedgehog pathway. Cell Communication and Signaling15: 35.
3. Liu M.,Li Y.,LiuA.,LiR.,SuY.,DuJ.,LiC., ZhuA.J. (2016) The exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development.eLife5: e17200.
4. DuJ.,ZhangJ.,HeT.,LiY.,SuY.,TieF.,LiuM.,HarteP., ZhuA.J. (2016) Stuxnet Facilitates the Degradation of Polycomb Protein during Development.Developmental Cell37: 507-19.
5. Geisbrecht E. R., Sawant K., Su Y., Liu Z.C., Silver D.L., Burtscher A., Wang X., Zhu A.J., McDonald J.A. (2013) Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration. Developmental Dynamics242: 414-31.
6. Zhang J., Liu M., Su Y., Du J., Zhu A.J. (2012) A targeted in vivo RNAi screen reveals deubiquitinases as new regulator of Notch signaling.G3: Genes, Genomes, Genetics 2: 1563-75.
7. Su Y., Ospina J.K., Zhang J., Michelson A., Schoen A.M., Zhu A.J. (2011) Sequential phosphorylation of Smoothened transduces graded Hedgehog signaling. Science Signaling4: ra43.
8. Du J., Zhang J., Su Y., Liu M., Ospina J.K., Zhu A.J. (2011) in vivoRNAi Screen reveals neddylation genes as novel regulators of Hedgehog signaling. PLoS ONE6: e24168.
9. Su Y., Zhang L., Gao X., Meng F., Wen J., Zhou H., Meng A., Chen Y. (2007) The evolutionally conserved activities of Dapper2 in antagonizing TGF-? signaling. FASEB Journal21: 682-90.
10. Lin X.^#, Duan X.^#, Liang Y.^#, Su Y.^#, Wrighton K.H., Long J., Hu M., Davis C.M., Wang J., Brunicardi F.C., Shi Y., Chen Y., Meng A., Feng X. (2006) PPM1A functions as a Smad phosphatase to terminate TGF? signaling.Cell125: 915-28.
11. Zhang L.^#, Zhou H.^#, Su Y.^#, Sun Z., Zhang H., Zhang L., Zhang Y., Ning Y., Chen Y., Meng A. (2004) Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of Nodal receptors. Science306: 114-7.
12. Zhao C., Shi K., Su Y., Liang L., Yan Y., Postlethwait J., Meng A. (2003) Two variants of zebrafish p100are expressed during embryogenesis and regulated by Nodal signaling. FEBS Letters543: 190-5.
13. Zhao C., Zhang Y., Su Y., Meng A. (2002) Somite-specific expression of a novel fibronectin variant FN3 is negatively regulated by SHH. Chinese Science Bulletin47: 1807-11.
14. Sun Z., Shi K.,Su Y.,Meng A.(2002) A novel zinc finger transcription factor resembles krox-20in structure and in expression pattern in zebrafish. Mechanisms of Development 114: 133-5.
15. Su Y.and Meng A. (2002) The expression of gbx-2during zebrafish embryogenesis. Mechanisms of Development113: 107-10.
16. Li M., Su Y., Meng A. (2002) Induction of cranial and posterior trunk neural crest by exogenous retinoic acid in zebrafish.Chinese Science Bulletin47: 1105-8.