付强，男，医学博士。副教授、免疫学硕士研究生导师、药学硕士研究生导师。山东省免疫学会生殖免疫学会副主任委员、中国免疫学会会员、山东省高校优秀青年人才、国家自然科学基金评审专家、多个国际权威期刊的审稿人。现正在主持国家自然科学基金面上项目1项。已经主持完成国家自然科学基金面上项目、山东省自然科学基金重点项目、山东省自然科学基金和校级课题各1项；参与4项国家自然科学基金项目和多项省部级课题研究。获得山东省高等学校优秀中青年骨干教师国际合作访学项目的资助，在美国北卡罗莱纳大学微生物学和免疫学系做访问****；并在UNC Lineberger肿瘤研究中心开展了博士后的课题研究合作。在J EXP MED, Oncogene等国际杂志上共发表SCI收录的文章20余篇，JCR一区和二区文章6篇，总影响因子大于100。
教育经历
2011/09-2014/07，复旦大学，博士
2001/09-2004/07，青岛大学，硕士
1996/09-2001/07，青岛大学，学士
工作经历
2016/07-2017/05，美国北卡罗莱纳大学，博士后
2015/12-2016/06，美国北卡罗莱纳大学，访问****
2013/01-至今，滨州医学院，副教授
2004/07-2012/12，滨州医学院，讲师

主持的科研项目
1、国家自然科学基金面上项目， STATs调控蜕膜NK细胞功能性发育的分子机制、2016/1-2019/12、55万元、在研、主持。
2、国家自然科学基金面上项目， LAIRs调节人早孕期蜕膜NK细胞功能的分子机制、2014/01-2017/12、70万元、已结题、主持。
3、山东省自然科学基金重点项目，JAK-STAT 信号通路对蜕膜NK细胞功能表型的调控作用、2015/7-2016/12、30万、已结题、主持。
4、山东省自然科学基金项目，感染对蜕膜NK细胞和DC功能以及相互作用影响的分子机制研究、2011/09-2014/08、6万元、已结题、主持。

SELECTED PUBLICATIONS (* Corresponding author ¹Co-first author)
(1) Qiang Fu*, Xuejing Man, Xin Wang, Nannan Song, Yuanbin Li, Jiangnan Xue, Yufei Sun, Wei Lin*. CD83⁺CCR7⁺ NK cells induced by interleukin 18 by dendritic cells promote experimental autoimmune uveitis. Journal of Cellular and Molecular Medicine. DOI: 10.1111/jcmm.14081.2018
(2) Qing Zhang, Jinjing Xu, Jiage Ding, Hongyan Liu, Huizhong Li, Hailong Li, Mengmeng Lu, Yangna Miao, Zhenzhen Wang, Qiang Fu*, Junnian Zheng*. Bortezomib improves adoptive carbonic anhydrase IX-specific chimeric antigen receptor-modified NK92 cell therapy in mouse models of human renal cell carcinoma. ONCOLOGY REPORTS. 40: 3714-3724. 2018
(3) Xuebiao Wu, Xiaoli Li, Fu Q¹, Qianhua Cao, Xingyu Chen, Mengjie Wang, Jie Yu, Jingpei Long, Jun Yao, Huixin Liu, Danping Wang, Ruocen Liao, and Chenfang Dong*. AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program. Journal of Experimental Medicine. 214 (4): 1065-1079. 2017 (IF: 11.99)
(4) Liu Y,Ye X,Zhang JB,Ouyang H,Shen Z,Wu Y,Wang W,Wu J,Tao S,Yang X,Qiao K,Zhang J,Liu J,Fu Q*,Xie Y*. PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation. Oncogene. 34(44):5524-35. 2015 (IF: 8.549)
(5) Fu Q*, Yufei Sun, Yu Tao, Hailan Piao, Xiaoqiu Wang, Xiying Luan, Meirong Du, Dajin Li*. Involvement of the JAK-STAT pathway in collagen regulation of decidual NK cells. Am J Reprod Immunol. 78(6). 2017 (IF:2.75)
(6) Lin W*, Man X, Li P, Song N, Yue Y, Li B, Li Y, Sun Y, Fu Q*. NK cells are negatively regulated by sCD83 in experimental autoimmune uveitis. Scientific Reports. 7(1): 12895. 2017 (IF:4.259)
(7) Fu Q, Liu P, Sun X, Huang S, Han F, Zhang L, Xu Y, Liu T*. Ribonucleic acid interference knockdown of IL-6 enhances the efficacy of cisplatin in laryngeal cancer stem cells by down-regulating the IL-6/STAT3/HIF1 pathway. Can Cel Int. 17:79-92. 2017(IF:3.96)
(8) Fu Q, Man X, Yu M, Chu Y, Luan X, Piao H, Xue J, Jin C* Human decidua mesenchymal stem cells regulate decidual NK cell function via interactions between collagen and leukocyte-associated immunoglobulin-like receptor 1. Mol Med Rep. 16: 2791-8. 2017 (IF:1.922)
(9) Tingyan Liu, Pengruofeng Liu, Yuan Li, Caixia Cui1, Lili Dai, Xuehua Zhou, Changzhu Jin, Fu Q*. Inhibition of STAT3 with shRNA enhances the chemosensitization of cisplatin in laryngeal carcinoma stem cells. Int J Clin Exp Pathol. 10 (6):6512-6519. 2017(IF:1.4)
(10) Yang DX, Yuan W, Lv CJ, L NE, Liu TS, Wang L, Sun YF, Qiu XS*, Fu Q*. Dihydroartemisinin supresses inflammation and fibrosis in bleomycine-induced pulmonary fibrosis in rats. Int J Clin Exp Pathol. 8(2):1270-1281. 2015 (IF: 2.242)
(11) Dong MH, Zhang Q, Wang YY, Zhou BS, Sun YF, Fu Q*. Euphorbia fischeriana Steud inhibits melanoma via modulation of the PI3K/Akt signaling pathway. EXP THER MED11(4):1475-1480. 2016 (IF: 1.269)
(12) Fu Q, Tao Y, Piao H, Du MR, Li DJ*. Trophoblasts and Decidual Stromal Cells Regulate Decidual NK Cell Functions Via Interaction between Collagen and LAIR-1. Am J Reprod Immunol. 71(4): 368-378, 2014 (IF: 3.05)
(13) Yuan W, Liu W, Li J, Li X, Sun X, Xu F, Man X*, Fu Q*. Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes. Int J Clin Exp Pathol. 7(7):3957-65. 2014 (IF: 2.242)
(14) Xu X, Fu Q¹, Zhang Q, Zhao M, Gao Z, Liu X, Liu Y, Hu X*. Changes of human decidual natural killer cells cocultured with YFP-Toxoplasma gondii: implications for abnormal pregnancy. Fertil Steril. 99(2):427-32. 2013 (IF: 4.295)
(15) Hu T*, Fu Q¹, Liu X, Zhang H, Dong M. Increased acetylcholinesterase and capase-3 expression in the brain and peripheral immune system of focal cerebral ischemic rats. J Neuroimmunol. 211(2):84-91, 2009 (IF: 2.901)
(16) Jie Mei, WenJie Zhou, XiaoYong Zhu, Han Lu, Ke Wu, HuiLi Yang, Qiang Fu,
ChunYan Wei, KaiKai Chang, LiPing Jin, Jian Wang, YongMing Wang, DaJin Li, Ming-Qing Li. Suppression of autophagy and HCK signaling promotes PTGS2high FCGR3? NK cell differentiation triggered by ectopic endometrial stromal cells. Autophagy 14 (8):1376–1397. 2018 (IF: 11.1)
(17) Juanjuan Zhao, Liang Cheng, Hongbo Wang, Haisheng Yu, Bo Tu, Fu Q, Guangming Li, Qi Wang, Yanling Sun, Xin Zhang, Zhenwen Liu, Weiwei Chen, Liguo Zhang, Lishan Su, Zheng Zhang. Infection and depletion of CD4+ group-1 ILC by HIV via type-1 interferon pathway. PLOS Pathogens.14(1). 2018(IF: 6.608)
(18) Li Y, Zhang J, Zhang D, Hong X, Tao Y, Wang S, Xu Y, Piao H, Yin W, Yu M, Zhang Y, Fu Q, Li D, Chang X, Du M. Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss. Science Signaling. 10 (498). 2017 (IF:6.378)
(19) Zhang Q, Tian K, Xu J, Zhang H, Li L, Fu Q, Chai D, Li H, Zheng J. Synergistic effects of cabozantinib and EGFR-specific CAR-NK-92 cells in renal cell carcinoma. Journal of Immunology Research. 4:**. 2017 (IF:3.298)
(20) Piao HL, Wang SC, Tao Y, Fu Q, Du MR.CXCL12/CXCR4 signal involved in the regulation of trophoblasts on peripheral NK cells leading to Th2 bias at the maternal-fetal interface.Eur Rev Med Pharmacol Sci. 19(12):2153-61, 2015 (IF: 1.213)
(21) Li YH, Zhou WH, Tao Y, Wang SC, Jiang YL, Zhang D, Piao HL, Fu Q, Li DJ, Du MR. The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy. Cell Mol Immunol. 13(1):73-81. 2016 (IF: 4.185)
(22) Du MR, Guo PF, Piao HL, Wang SC, Sun C, Jin LP, Tao Y, Li Y, Zhang D, Zhu R, Fu Q, Li DJ*. Embryonic Trophoblasts Induce Decidual Regulatory T cell Differentiation and Maternal-Fetal Tolerance through Thymic Stromal Lymphopoietin Instructing Dendritic Cells. J Immunol. 192(4):1502-11. 2014 (IF: 5.362)
(23) Tao Y, Li YH, Piao HL, Zhou WJ, Zhang D, Fu Q, Wang SC, Li DJ, Du MR*.CD56^brightCD25⁺NK cells are preferentially recruited to the maternal/fetal interface in early human pregnancy. Cell Mol Immunol. 12(1):77-86. 2015 (IF: 4.185)
(24) Wang SC, Tang ChL, Piao HL, Zhu R, Sun Ch, Tao Y, Fu Q, Li DJ, Du MR. Cyclosporine A promotes in vitro migration of human first-trimester trophoblasts via MAPK/ERK1/2-mediated NF-κB and Ca²⁺/calcineurin/NFAT signaling. Placenta. 34(4):374-80.2013 (IF: 3.285)
(25) Piao HL, Tao Y, Zhu R, Wang SC, Tang CL, Fu Q, Du MR*, Li DJ*. The CXCL12/CXCR4 axis is involved in the maintenance of Th2 bias at the maternal/fetal interface in early human pregnancy. Cell Mol Immunol. 9:423-30. 2012 (IF: 4.185)
(26) Piao HL, Wang SC, Tao Y, Zhu R, Sun C, Fu Q, Du MR, Li DJ*. Cyclosporine A enhances Th2 bias at the maternal-fetal interface in early human pregnancy with aid of the interaction between maternal and fetal cells. PLoS One. 7(9): e45275. 2012 (IF: 3.534)
(27) Zhang H, Hu X, Liu X, Zhang R, Fu Q, Hu X*. The Treg/Th17 imbalance in Toxoplasma gondii-infected pregnant mice. Am J Reprod Immunol. 67:112-121. 2012 (IF: 3.05)
(28) Zhang R, Zhang H, Liu X, Fu Q, Xu X, Hu X*. The immunoprotective role of interleukin-10 in abnormal pregnancy outcome induced by Toxoplasma gondii infection. Gynecol Obstet Invest. 73(3):223-9. 2012 (IF: 1.03)
(29) Xue J, Zhang X, Zhao H, Fu Q, Cao Y, Wang Y, Feng X, Fu A. Leukocyte-associated immunoglobulin-like receptor-1 is expressed on human megakaryocytes and negatively regulates the maturation of primary megakaryocytic progenitors and cell line. Biochem Biophys Res Commun. 405: 128-33. 2011 (IF: 2.58)