李宪凯 副主任医师
硕士招生类型：学术型、专业型
硕士招生专业：内科学（心血管内科学）
博士招生类型：
博士招生专业：
所在院系：附属第十人民医院
联系方式：lixiankai@tongji.edu.cn
课题组链接：
研究方向
主要任职
科研业绩

冠状动脉粥样硬化
腹主动脉瘤基础研究




1. 中国医师协会介入分会心脏介入委员
2. 中国医师协会心血管内科分会代谢性心血管疾病专业委员会委员
3. 中国老年学学会心血管病精准医疗专家委员会青年委员
4. 中国老年医学会高血压分会青年委员
5. 中国肺栓塞救治团队联盟专家委员
6. 上海市医师协会会员



Publications
[1] Jiang D, Zhuang J, Peng W, Lu Y, Liu H, Zhao Q,Chi C, Li X, Zhu G, Xu X, Yan C, Xu Y, Ge J, Pang J.Phospholipase Cγ1 Mediates Intima Formation Through Akt-Notch1 SignalingIndependent of the Phospholipase Activity. J Am Heart Assoc. 2017 Jul11;6(7).
[2] Jianhui Zhuang, Yang Han, Dachun Xu, Guofu Zhu, Shekhar Singh,Luoman Chen, Mengyun Zhu, Wei Chen, Yawei Xu, Xiankai Li. Comparisonof circulating dendritic cell and monocyte subsets at different stages ofatherosclerosis: insights from optical coherence tomography. BMC CardiovascDisord. 2017 Oct 18;17(1):270. doi:10.1186/s12872-017-0702-3. (通讯作者)
[3] Luoman Chen, Jianhui Zhuang, Shekhar Singh, Kai Wang, MengtingXiong, Dachun Xu, Wei Chen, Jinjiang Pang, Yawei Xu and Xiankai Li.XAV939 inhibits intima formation by decreasing VSMC proliferation and migrationthrough blocking Wnt signaling. J Cardiovasc Pharmacol. 2016Dec;68(6):414-424. (通讯作者)
[4] ZhaoM, Li X, Zheng L, Zhang J, Zhang L, Nguyen T, Sun Y, Li J.Optimal Blood Pressure in Patients after Stroke in Rural Areas of China. JStroke Cerebrovasc Dis. 2016 Feb;25(2):270-80. （共为第一作者）
[5] JianhuiZhuang, Guofu Zhu, Xiankai Li, Yawei Xu. Comparison ofcirculating dendritic cells and monocyte subsets at different stages ofatherosclerosis. JACC. 2014;63(12):A52-53.( suppl A) (Correspondingauthor)
[6] LiangC, Li X, Xu Y, Chen Q, Wu Y, Wang W, Li W, Qiu M. KCNE1 rs**Polymorphism Increases the Risk of Atrial Fibrillation: A Meta-Analysis of 10Studies. PLoS One. 2013 Jul 18;8(7):e68690.doi: 10.1371/journal.pone.**. Print 2013. (共为第一作者)
[7] Xu D,Chen W, Li X, Zhang Y, Li X, Lei H, Wei Y, Li W, Hu D, Wedick NM,Wang J, Xu Y, Li J, Ma Y. Factors associated with blood pressure control inhypertensive patients with coronary heart disease: evidence from the ChineseCholesterol Education Program. PLoS One. 2013 May 15;8(5):e63135. doi:10.1371/journal.pone.**. Print 2013. (共为第一作者)
[8] XiankaiLi,Joseph W. Villard, Yongjian Ouyang, Joel E. Michalek, Refat Jabara, Dan Sims,Nate Kemp, Tim Glynn, Christopher Banas, Steven R. Bailey, Marc D. Feldman.Safety and efficacy of frequency domain optical coherence tomography. Eurointervention.2011;7(4):497-504.
[9] LiX, Luo Y, Xu Y, Li J, and HuD. Relationship of Ankle-brachial Index with All-cause Mortality andCardiovascular Mortality after 3 years Follow up：The China Ankle-brachial Index CohortStudy. J Hum Hypertens. 2010;24(2):111-116.
[10]Xiankai Li, Yawei Xu, Jue Li, Dayi Hu. The Gender Differences inBaseline Characters and Statins Intervention among Outpatients with CoronaryHeart Disease in China: the China Cholesterol Education Program (CCEP). Clincardiol. 2009; 32(6):308-314.
[11]YingyiLuo, Xiankai Li, Jue Li, Xiaoming Wang, Yuanxi Xu, Yongxia Qiao,Dayi Hu. Peripheral arterial disease, chronic kidney disease, andmortality-----The Chinese Ankle Brachial Index Cohort Study. Vascularmedicine. 2009;15(2):107-112. (共为第一作者)
[12] Xiankai Li，Jue Li, Thach Nguyen,Mingzhong Zhao, Liqiang Zheng, Buaijiaer Hasimu, Jinming Yu, Yingyi Luo, DayiHu. Effect of statins and calcium channel blockers on all-cause mortality andcardiovascular and cerebrovascular disease mortality in 958 Chinesehospitalized patients with peripheral arterial disease after 13 months offollow-up. J Health Sci. 2007;53(2):226-233.
参编书籍
1. Chapter 7, < >, Jack Chen, Xiankai Li, Thach Nguyen, Phan NamHung, Tejas Patel, Shigeru Saito. In < > Edited by Thach N.Nguyen, Dayi Hu,Shaoliang Chen, Moo-Hyun Kim, Shigeru Saito, Cindy Grines, C.Michael Gibson,Steven R.Bailey. Wiley-BlackWell. ISSN：；Publishing House: Wiley-Blackwell; 2012.
2. Chapter 14, < >, Xiankai Li, Tuan D. Nguyen, Sim Kui Hian,and Thach Nguyen, in < > edited by Dayi Hu, Thach N. Nguyen, Moo-Hyun Kim, TakaoKwan, Shigeru Saito. ISSN：；Publishing House: PMPH-USA Limited; 2010.
3. Chapter 12, < >, Deepak Joshi, Rajasekhar Nekkanti, Mavin H. Eng, MadhuiRoberts. Ngoc Quang Nguyen, Xiankai Li and Michael Rinaldi in< > editedby Thach N. Nguyen, Dayi Hu, Shaoliang Chen, Moo-Hyun Kim, Cindy Grines. ISBN:；Publishing House: Wiley-BlackWell; 2016.

主持课题
1. 上海市科委科研项目,《西藏日喀则市人民医院“胸痛中心”建设》
2. 西藏自然科学基金，治疗性红细胞单采术治疗慢性高原病合并肺动脉高压的疗效和机制探讨
3. 上海市第十人民医院国家自然科学基金院内培养项目，Caspase4/11介导的炎症反应在腹主动脉瘤形成中的作用和机制探讨
4. 上海市卫计委面上项目，Wnt信号通路在支架内再狭窄中的作用机制
5. 国家自然科学基金青年科学基金项目，新型纳米颗粒靶向检测动脉粥样硬化斑块中的巨噬细胞
6. 上海市卫生局青年科研项目，采用纳米颗粒和OCT检测动脉硬化斑块中的巨噬细胞
上海市优秀青年医师培养计划，《光学相干断层成像术和流式细胞术评估冠状动脉斑块》