唐伦先 主任医师，副教授
硕士招生类型：学术型；专业型
硕士招生专业：急诊医学
博士招生类型：学术型；专业型
博士招生专业：急诊医学
所在院系：附属东方医院
联系方式：456tlx@163.com
课题组链接：
研究方向
主要任职
科研业绩


急性呼吸窘迫综合征的分子发病机制与临床
The potential molecular mechanism andclinical aspects of ARDS
脓毒症的免疫功能障碍
Theimmunological dysfunction of sepsis






中国中西医结合学会灾难分会创伤学组常委
Member of the standing committee of society of disaster and trauma of Chinesetraditional Chinese Medicine
中国医学救援协会重症医学分会委员
Committee member of society of Criticalcare branch of Chinese salvage medicine
上海市中西医结合学会急危重症、抗感染分会委员
Committee member of society of Criticalcare and Emergency/ anti-inflammatory branch of Shanghai traditional ChineseMedicine
同济大学附属东方医院急诊内科南院执行主任
Executive chief of Internal EmergencyMedicine in south branch of East Hospital/Tongji
University




美国布朗大学访问****，一直致力于急性肺损伤/急性呼吸窘迫综合征的基础和临床研究，第一作者发表论文30余篇，其中SCI论文10篇。先后完成科委，卫计委课题2项，新区优秀学科带头人1项，国际自然科学基金1项。目前主持国家自然科学基金面上项目1项、省部级自然基金重点项目1项和浦东新区领先人才计划1项，科研经费近200万元。培养硕士研究生9名，毕业5名。博士在读1名。
Visiting doctor of Brown Universityin USA. Research interests include projects looking at the potential molecular mechanismand clinical aspects of ARDS. More than 30 papersof 1^st author hadbeen published including 10 SCI papers. Two grants had been accomplished. Twogrants from NSFC and key programs of provincial grants and Leading talents ofHealth Bureau of Pudong New District are now in progress.
附主要SCI论文：
1. Liu X, Jiang S, Zhang Q, Xu S, Bao X, Cao W, Bai J, Tang L*（唐伦先）.Tim-3Regulates
Tregs'Ability to Resolve the Inflammation and Proliferation of Acute Lung Injury byModulating Macrophages Polarization.Shock. 2018;50(4):455-464. (IF 3.113)
2.Tang L（唐伦先）, Zhang H, Wang C, Li H, Zhang Q, Bai J. M2a and M2c
macrophagesubsets ameliorate inflammation and fibroproliferation in acute lung
injurythrough interleukin 10 pathway. Shock 2017(1);48:119-129. (IF 3.113)
3.TangL（唐伦先）, Bai J, Chung CS,Lomas-Neira J, Chen Y, Huang X, Ayala A*. Active
players inresolution of shock/sepsis induced indirect lung injury:
immunomodulatoryeffects of Tregs and PD-1.JLeukoc Biol. 2014; 96(5):
809-820. (IF4. 304)
4.Tang L（唐伦先）, Bai J, ChungCS, Lomas-Neira J, Chen Y, Huang X, Ayala A*. PD-L1
regulatesthe Tregs' capacity to repress shock/sepsis induced indirect lung injury (iALI)by recruiting phosphatase SHP-1.Shock.2015;43(1):47-54.(IF 3.113)
5.Bai J, Tang L(唐伦先，共同第一作者), Lomas-Neira J, Chen Y, McLeish KR,Uriarte SM, Chung CS, Ayala A*. TAT-SNAP-23treatment inhibits the priming of neutrophil functionscontributing to shock and/or sepsis-induced extra-pulmonary acute lung injury .Innate Immun. 2015;21(1):42-54. (IF 2.83)6.Zhou Y, Tang L(唐伦先，共同第一作者), Lin M, Xu S, Bai J*, Song H*.Expression of Cytotoxic T-LymphocyteAntigen 4 on CD4+ and CD8+ T Cells Is Increased in Acute Lung Injury. DNA CellBiol.2013,32(12): 722-726. (IF 2.574 )7. Tang L（唐伦先）, Li Q, Bai J*, Zhang H, LuY, Ma S. Severe pneumonia mortality in elderlypatients is associated with downregulation of Toll-like receptors 2 and 4 onmonocytes. Am J Med Sci. 2014;347(1):34-41. (IF 1.515)8. Song H, Tang L(唐伦先，共同第一作者), Xu M, Li H, Xu S, Li G, Bao X, Sun B, ChengT, Yang Q, Bai J*. CD86polymorphism affects pneumonia-induced sepsis bydecreasing gene expression in monocytes. Inflammation.2015;38(2):879-885. (IF 2.618)9.包晓玮，孙宏，杨倩，刘显东，陈春香，白建文，唐伦先（通讯作者）^*.共刺激分子程序性死亡配体-1在急性肺损伤中的作用及机制初探.中华危重病急救医学. 2016,28(6):498-50310.孙宏，刘显东，吕迪宇，包晓玮，白建文，唐伦先（通讯作者）^*.转化生长因子-β/Smad信号通路对急性肺损伤小鼠免疫平衡的影响.中华危重病急救医学. 2016,28(11):967-972