蒋小华 主任医师，副教授
硕士招生类型：学术型；专业型
硕士招生专业：外科学（普外科）
博士招生类型：专业型
博士招生专业：外科学（普外科）
所在院系：附属东方医院
联系方式：jiangxiaohuash@163.com
课题组链接：
研究方向
主要任职
科研业绩

胃癌和结直肠癌的基础和临床研究 basic and clinical research for gastric and colorectal cancer
美国外科学院院士（FACS）
中华医学会外科分会外科营养学组委员
中国医师协会外科外科医师分会临床营养医师委员会委员
中国抗癌协会肿瘤支持治疗专业委员会委员
中国医师协会结直肠肿瘤医师分会青委会委员
中国医师协会结直肠肿瘤医师分会MDT委员会委员
中国医师协会结直肠肿瘤医师分会单孔腹腔镜委员会委员
中华医学会消化分会炎症性肠病学组青年委员
中华医学会肠外肠内营养专业委员会胃肠病与营养学组委员
世界内镜医师协会委员
国际胃癌学会会员
欧洲消化外科学会会员
欧洲消化道肿瘤学会会员
《世界华人消化杂志》编委
《Translational Surgery》 编委
Fellow of American College of surgery (FACS)
Member, surgical nutrition group, surgical branch, Chinese Medical Association
Member of the Committee of clinical nutritionists, surgical surgeon branch, Chinese Medical Doctor Association
Member of cancer support and treatment Committee of China Anti Cancer Association
Member of the Youth Committee of colorectal cancer doctors branch, Chinese Medical Association
Member of MDT Committee of colorectal cancer doctors branch of Chinese Medical Doctor Association
Member of single port laparoscopy Committee, colorectal cancer physicians branch, Chinese Medical Association
Young member of inflammatory bowel disease group, digestive branch, Chinese Medical Association
Member of Gastroenterology and nutrition group of parenteral and Enteral Nutrition Committee of Chinese Medical Association
Member of the World Association of endoscopists
Member of the international society of gastric cancer
Member of the European Society of digestive surgery
Member of the European Society of gastrointestinal oncology
Editorial board member of World Chinese digest Journal
Editorial board member of translational surgery
论文发表（Publications）:1.Jiang X, Li N, Li YX, et al. Intestinal permeability in patients after surgical trauma and the role of enteral nutrition versus parenteral nutrition. World J Gastroenterol 2003; 9: 1878-1880. ( IF 2.092 )
2.Jiang X, Li N, Zhu WM, et al. Role of postoperative immune enhancing enteral nutrition on immune, inflammatory response and clinical outcome. Chin M J 2004; 117(6) :835-839. ( IF 0.952 )
3.Jiang X, Zhu WM, Li N, et al. Effects of continuous enteral L-Arginine supplementation on intestinal adaptation in a rat model of short bowel syndrome. Asian Pacific Journal of Clinical Nutrtion. Asia Pac J Clin Nutr 2007;16 (3):554-560. ( IF 1.214 )
4.Jiang X, Zhang W, Kayed H, et al. Loss of ONECUT1 expression in human pancreatic cancer cells. Oncology Reports 2008;19(1):157-163. ( IF 1.588 )
5.Jiang X, Abiatari I, Kong B, et al. Pancreatic Islet and Stellate Cells Are the Main Sources of Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Pancreatic Cancer. Pancreatology 2009;13;9(1-2):165-172. ( IF 2.195 )
6.Jiang X, Gillen S, Esposito I, et al. Reduced expression of the membrane skeleton protein beta1-spectrin (SPTBN1) is associated with worsened prognosis in pancreatic cancer. Histol Histopathol. 2010;25(12):1497-506. ( IF 2.404 )
7.Jiang X, Rieder S, Giese NA, et al. Reduced alpha-Dystroglycan Expression Correlates with Shortened Patient Survival in Pancreatic Cancer. J Surg Res. 2011;171(1):120-6. ( IF 2.176 )
8.Jiang X, Hiki N, Nunobe S, et al. Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer. Surg Endosc. 2011 Apr;25(4):1182-6. ( IF 3.307 )
9.Jiang X, Hiki N, Yoshiba H, et al. Laparoscopy-assisted gastrectomy in patients with previous endoscopic resection for early gastric cancer. Br J Surg. 2011 Mar;98(3):385-90. ( IF 4.077 )
10.Jiang X, Hiki N, Nunobe S, et al. Laparoscopy-assisted subtotal gastrectomy with very small remnant stomach: A novel surgical procedure for selected early gastric cancer in the upper stomach. Gastric Cancer. 2011 Jun;14(2):194-9. ( IF 2.614 )
11.Jiang X, Hiki N, Nunobe S, et al. Postoperative Outcomes and Complications after Laparoscopy-assisted Pylorus-preserving Gastrectomy for Early Gastric Cancer. Ann Surg. 2011 May;253(5):928-33. ( IF 7.9 )
12.Jiang X, Hiki N, Nunobe S, et al. Postoperative Pancreatic Fistula and the Risk Factors of Laparoscopy-Assisted Distal Gastrectomy for Early Gastric Cancer. Ann Surg Oncol. 2012 Jan;19(1):115-21. (IF 4.18)
13.Jiang X, Hiki N, Nunobe S, et al. Prognostic importance of the inflammation-based Glasgow prognostic score in patients with gastric cancer. Br J Cancer. 2012;107(2):275-9. (IF 5.042)
14.Pan Z, Jiang XH, Zhou JH, Ji ZL. Transumbilical single-incision laparoscopic appendectomy using conventional instruments: the single working channel technique. Surg Laparosc Endosc Percutan Tech. 2013 Apr;23(2):208-11. (Co-first author) (IF 0.876 )
15.Jiang W, Zhao S, Jiang X, et al. The circadian clock gene Bmal1 acts as a potential anti-oncogene in pancreatic cancer by activating the p53 tumor suppressor pathway. Cancer Lett. 2016;371(2):314-25. (Co-first author) (IF 6.491)
16.Zhang S, Du T, Jiang X, Song C. Laparoscopic Appendectomy in Children With Perforated Appendicitis: A Meta-Analysis. Surg Laparosc Endosc Percutan Tech. 2017 Aug;27(4):262-266. （IF 0.986 correspondance author）
17.Chen B, Li Q, Zhou Y, Wang X, Zhang Q, Wang Y, Zhuang H, Jiang X, Xiong W. The long coding RNA AFAP1-AS1 promotes tumor cell growth and invasion in pancreatic cancer through upregulating the IGF1R oncogene via sequestration of miR-133a. Cell Cycle. 2018;17(16):1949-1966. （IF 3.304 co-correspondance author）
18.Zhang S, Yang Y, Yan D, Yuan B, Jiang X, Song C. Internet videos and colorectal cancer in mainland China: a content analysis. BMC Med Inform Decis Mak. 2018 Dec 4;18(1):129. （IF 2.134 co-correspondance author）
19.Jiang X, Li Q, Zhang S, Song C, Zheng P. long noncoding rna gihcg induces cancer progression and chemoresistance and indicates poor prognosis in colorectal cancer. OncoTargets and Therapy 2019:12 1059–1070（IF 2.656 correspondance author）
获取科研资助情况：1.国家自然科学基金青年基金：胰星状细胞促进胰腺癌侵袭和转移及其分子机制研究（项目号：**）。2010.1 – 2012.12项目负责人
2.教育部留学归国基金 ：胰星状细胞在胰腺癌生长和转移中的作用及其分子机制的实验研究。 2010.10 – 2013.10项目负责人
3.江苏省医学重点人才：胰腺肿瘤微环境在胰腺癌发展和转移中的中的作用及其分子机制 (RC**) 2011-2015年 项目负责人
4.江苏省临床医学科技专项：胆囊息肉微创治疗新技术的创建及其推广应用研究(BL**) 2012.9-2015.8 共同负责人
5.国家重点基础研究计划（973）：纳米材料调控自噬在肿瘤诊疗中的应用2013-2017子项目第二负责人
6.上海市自然基金： microRNA-155促进炎症相关性结直肠癌发生发展及其相关机制的研究 (14ZR**) 2014.7-2017.6项目负责人
7.浦东新区卫生系统学科带头人（PWRD2014-04）： 2014.10-2018.9 项目负责人
8.上海市人才发展基金资助项目：IL-15 mutant/Fc对炎症性肠病肠粘膜T细胞分化和凋亡的调控作用及机制研究（201561）项目负责人
9.国家自然基金面上项目：Onzin在肠炎至结直肠癌转变中的作用及机制研究(**) 2017.1-2020.12项目负责人
10.浦东新区卫生系统特色专病：胃癌的微创治疗（PWZzb2017-05）2017.9-2020.6 项目负责人
Research grant：1. NSFC Youth Fund: pancreatic stellate cells promote the invasion and metastasis of pancreatic cancer and its molecular mechanism (Project No.: **). Project leader from January 2010 to December 2012
2.Ministry of Education Fund for returned students: Experimental Study on the role of pancreatic stellate cells in the growth and metastasis of pancreatic cancer and its molecular mechanism. 2010.10 – 2013.10
3.Key medical talents in Jiangsu Province: the role of pancreatic tumor microenvironment in the development and metastasis of pancreatic cancer and its molecular mechanism (rc**) project leader, 2011-2015
4.Jiangsu Province clinical medical science and technology project: the establishment and promotion of new minimally invasive treatment technology for gallbladder polyps (bl**) Co director, 2012.9-2015.8
5.National key basic research program (973): application of nanomaterials to regulate autophagy in cancer diagnosis and treatment
6.Shanghai Natural Science Foundation: Research on microRNA-155 promoting the occurrence and development of inflammation related colorectal cancer and its related mechanism (14zr**), project leader, July 2014-june 2017
7.Discipline leader of health system in Pudong New Area (pwrd2014-04): project leader from October 2014 to September 2018
8. Shanghai Talent Development Fund funded project: regulatory effect and mechanism of IL-15 mutant / FC on intestinal mucosal T cell differentiation and apoptosis in inflammatory bowel disease (201561)
9.NSFC general program: Research on the role and mechanism of onzin in the transformation from enteritis to colorectal cancer (**), project leader, January 2017 to December 2020
10. Special disease of health system in Pudong New Area: minimally invasive treatment of gastric cancer (pwzzb2017-05) project leader, September 2017-june 2020