杨斌 副主任医师，副教授
硕士招生类型：学术型；专业型
硕士招生专业：外科学（泌尿外科）
博士招生类型：专业型
博士招生专业：外科学（泌尿外科）
所在院系：附属第十人民医院
联系方式：yangbnju@gmail.com ; yangbin710@163.com
课题组链接：
研究方向
主要任职
科研业绩

前列腺癌的基础与临床研究：
前列腺癌早期诊断的融合靶向精准穿刺活检；
前列腺癌循环内皮祖细胞检测与临床意义;
前列腺癌微创手术的优化;
前列腺癌手术中扩大淋巴结清扫的临床意义;
寡转移前列腺癌的减瘤手术及其临床意义;
PSMA-PET/CT在前列腺癌精准诊治中的应用，前列腺癌的基因检测与精准治疗；
前列腺癌的耐药机制研究等
中国抗癌协会泌尿男生殖系统肿瘤精准医学学组委员；
中华医学会泌尿外科学分会泌尿男科工程学组委员；
中华医学会泌尿外科学分会青年委员会肿瘤学组委员；
中华医学会泌尿外科学分会青年委员会科学普及与传播组成员；
上海市医学会男科分会青年委员；
中国医药教育协会盆腔肿瘤专业委员会委员；
亚洲男科学协会青年委员
作为主持人承担各级科研项目10项，累计科研经费逾150万，包括国家自然科学基金2项，入选上海市浦江人才计划等。以第一作者和通讯作者发表学术论文二十余篇，多次国际会议口头发言，获中国发明专利授权两项，为多本SCI收录杂志审稿专家，参加多项全国多中心临床研究。作为主要参与者获教育部科学技术进步奖一等奖1项，华夏医学科技奖三等奖1项。
1.代表性论文（JCR2019影响因子）：1)Guo Y#, Mao S#, Zhang A#, Zhang J, Wang L, Wang R, Zhang W, Zhang Z, Wu Y, Cao X, Yang B*, Yao X*. Survival Significance of Patients With Low Prostate-Specific Antigen and High-Grade Prostate Cancer After Radical Prostatectomy, External Beam Radiotherapy, or External Beam Radiotherapy With Brachytherapy. Front Oncol. 2019 Jul 19;9:638. doi: 10.3389/fonc.2019.00638. eCollection 2019. (Article, Co-Corresponding author, IF=4.848)
2)Guo Y#, Mao S#, Zhang A#, Wang R, Zhang Z, Zhang J, Wang L, Zhang W, Wu Y, Ye L, Yang B*, Yao X*. Prognostic Significance of Young Age and Non-Bone Metastasis at Diagnosis in Patients with Metastatic Prostate Cancer: a SEER Population-Based Data Analysis. J Cancer, 2019;10(3):556-567. (Article, Co-Corresponding author, IF=3.565)
3)Zhou L#, Xia J#, Wang P, Jia R, Zheng J, Yao X, Chen Y, Dai Y*, Yang B*. Autologous Smooth Muscle Progenitor Cells Enhance Regeneration of Tissue-Engineered Bladder. Tissue Eng Part A. 2018 Jul;24(13-14):1066-1081. (Article, Corresponding author, IF=3.496)
4)Liu G, Wu R, Yang B, Deng C, Lu X, Walker SJ, Ma PX, Mou S, Atala A, Zhang Y. Human Urine-Derived Stem Cell Differentiation to Endothelial Cells with Barrier Function and Nitric Oxide Production. Stem Cells Transl Med, 2018;7(9):686-698. (Article, IF=6.429).
5)Guo C#, Gu W#, Liu M, Peng Bo, Yao X, Yang B*, Zheng J*. Efficacy and safety of testosterone replacement therapy in men with hypogonadism: A meta-analysis study of placebo-controlled trials. Exp Ther Med, 2016;11(3):853-863. (Meta-analysis Article, Co-Corresponding author, IF=1.785)
6)Gu W#, Sun W#, Guo C, Yan Y, Liu M, Yao X, Yang B*, Zheng J*. Culture and characterization of circulating endothelial progenitor cells in patients with renal cell carcinoma. The Journal of urology, 2015;194(1):214-222. (Article, Co-Corresponding author, IF= 5.925)
7)Zhou L, Xia J, Qiu X, Wang P, Jia R, Chen Y, Yang B*, Dai Y*. In vitro evaluation of endothelial progenitor cells from adipose tissue as potential angiogenic cell sources for bladder angiogenesis. PLoS One, 2015;10(2):e**. (Article, Co-Corresponding author, IF=2.740)
8)Yang B#, Zhou L#, Peng B, Sun Z, Dai Y*, Zheng J*. In vitro comparative evaluation of recombinant growth factors for tissue engineering of bladder in patients with neurogenic bladder. The Journal of surgical research, 186(1):63-72, 2014. (Article, IF= 1.841)
9)Zhou L#, Yang B#, Sun C, Qiu X, Sun Z, Chen Y, Zhang Y*, Dai Y*. Coadministration of platelet-derived growth factor-BB and vascular endothelial growth factor with bladder acellular matrix enhances smooth muscle regeneration and vascularization for bladder augmentation in a rabbit model. Tissue engineering Part A, 19(1-2):264-276, 2013. (Article, Co-first author, IF= 3.496)
10)Bharadwaj S#, Liu G#, Shi Y, Wu R, Yang B, He T, Fan Y, Lu X, Zhou X, Liu H, Atala A, Rohozinski J, Zhang Y*. Multipotential differentiation of human urine-derived stem cells: potential for therapeutic applications in urology. Stem cells, 31(9):1840-1856, 2013. (Article, IF= 6.022)
11)Yang B, Zheng JH, Zhang YY*. Myogenic differentiation of mesenchymal stem cells for muscle regeneration in urinary tract. Chinese medical journal, 126(15):2952-2959, 2013. (Invited Review, IF= 1.585)
12)Guo C#, Yang B#, Gu W, Peng B, Xia S, Yang F, Wen D, Geng J, Zhang Y, Zheng J*. Intravesical resiniferatoxin for the treatment of storage lower urinary tract symptoms in patients with either interstitial cystitis or detrusor overactivity: a meta-analysis. PLoS One, 8(12):e82591,2013. (Meta-analysis Article, Co-first author, IF=2.740)
13)Yang B, Zhou L, Peng B, Dai Y, Zheng J*. Stem cells in a tissue-engineered human airway. Lancet, 379(9825):1487, 2012. (Correspondence, IF= 60.392).
14)Yang B#, Gu W#, Peng B*, Xu Y, Liu M, Che J, Geng J, Zheng J*. High level of circulating endothelial progenitor cells positively correlates with serum vascular endothelial growth factor in patients with renal cell carcinoma. The Journal of urology, 188(6):2055-2061, 2012. (Article, IF=5.925).
15)Yang B, Peng B, Zheng J*. Cell-based tissue-engineered urethras. Lancet, 378(9791):568-569, 2011. (Correspondence, IF=60.392).
16)Zhang YF, Guan YB, Yang B, Wu HY, Dai YT, Zhang SJ, Wang JP, Anoopkumar-Dukie S, Davey AK, Sun ZY*. Prognostic value of Her-2/neu and clinicopathologic factors for evaluating progression and disease-specific death in Chinese men with prostate cancer. Chinese medical journal, 124(24):4345-4349, 2011. (Article, IF=1.585).
17)Yang B, Zhou L, Sun Z, Yang R, Chen Y, Dai Y*. In vitro evaluation of the bioactive factors preserved in porcine small intestinal submucosa through cellular biological approaches. Journal of biomedical materials research Part A, 93(3):1100-1109, 2010. (Article, IF= 3.525).
18)Yang B, Zhang Y, Zhou L, Sun Z, Zheng J, Chen Y, Dai Y*. Development of a porcine bladder acellular matrix with well-preserved extracellular bioactive factors for tissue engineering. Tissue engineering. Part C, Methods, 16(5):1201-1211, 2010. (Article, IF=2.608).
19)郭亚东，杨斌，毛士玉，姚旭东. 减瘤手术在寡转移前列腺癌的临床应用及研究进展. 临床泌尿外科杂志. 2018, 33(4):280-284.
20)杨斌，顾闻宇，郑军华 姚旭东. 前列腺癌诊断标志物的研究进展. 现代泌尿外科杂志. 2016, 21(11):881-885.
21)周六化，杨斌，戴玉田. 组织工程膀胱的研究进展. 中华泌尿外科杂志. 2014, 35(11):876-878.
22)周六化，杨斌，夏佳东，王鹏基，陈赟，戴玉田. CM-DiI标记兔外周血平滑肌祖细胞可行性分析. 南京大学学报(自然科学). 2014, 50(1):1-8.
23)周六化，杨斌，王鹏基，夏佳东，章宜芬，陈赟，戴玉田. 异源性膀胱脱细胞基质移植修复兔膀胱缺损的局部和全身安全性评价. 中国修复重建外科杂志. 2013, 27(8):935-944.
24)郑军华*，顾闻宇，杨斌. 肿瘤新生血管抑制在前列腺癌治疗中的研究进展. 上海医学, 35(5):363-366, 2012.
25)顾闻宇， 杨斌，彭波，车建平，郑军华*. Xp11.2 易位/TFE3 基因融合相关性肾癌1例报道及文献复习. 临床泌尿外科杂志. 27(6):417-420, 2012.
26)杨斌，孙则禹，兰厚金，朱伟东，戴玉田*.从膀胱癌患者分离并培养人膀胱平滑肌细胞. 临床泌尿外科杂志, 25(4):299-302, 2010.
27)杨斌，陈贇，周六化，孙则禹，戴玉田*. 同时分离和培养兔外周血平滑肌祖细胞和内皮祖细胞. 南京大学学报 (自然科学版) , 46(1):92-99,2010.
2.国际会议摘要(口头发言)：1)Yang B, Cao X, Yang G, Guo Y, Mao S, Yao X. Evaluating the prognostic value of radical prostatectomy and radiation therapy on survival of patients with neuroendocrine prostate cancer: A retrospective study based on SEER database. European Urology Supplements, 2019;18(1):e1575. (2019 EAU Annual Meeting, Abstract).
2)Yang B, Gu W, Sun W, Guo C, Yao X, Zheng J. Quantification, culture and characterization of circulating endothelial progenitor cells in patients with renal cell carcinoma. European Urology Supplements, 2016;15(3);e219. (2016 EAU Annual Meeting, Abstract).
3)Yang B, Gu W, Guo C, Sun W, Che J, Liu M, Yao X, Zheng J. Tumour-derived vascular endothelial growth factor mobilizes circulating endothelial progenitor cells and contributes to vasculogenesis of renal cell carcinoma. European Urology Supplements, 2016;15(3);e220. (2016 EAU Annual Meeting, Abstract).
4)Yang B, Zhou L, Zheng J, Sun Z, Dai Y. Improvements of smooth muscle regeneration and vascularization in tissue-engineered bladder using autologous endothelial progenitor cells and exogenous bioactive factors. European Urology Supplements, 2010; 9(2):108-109. (2010 EAU Annual Meeting, Abstract).
3. 科技奖励：1)郑军华、许青、彭波、王光春、杨斌、李泉林、许云飞、刘敏、刘颖、李智、彭屹峰、刘彦君；泌尿系肿瘤的生物学行为研究和个体化策略治疗，教育部，科学技术进步奖一等奖，2013年1月。
2)郑军华、许青、彭波、王光春、许云飞、李泉林、杨斌、车建平；泌尿系肿瘤个体化治疗关键技术体系的建立和临床应用与推广，华夏医学科技奖三等奖，2013年12月
4.发明专利：1)杨斌，孙则禹，周六化，戴玉田 多孔的保留有生物活性因子的膀胱无细胞基质及制备方法 , 2012.07.25, 中国 , 专利号 ZL8.0。
2)杨斌，孙则禹，戴玉田 一种检测无细胞基质中保留的生物活性因子的方法， 2010.12.08, 中国，专利号 ZL9.5。