职称教授
硕士生导师科学学位专业名称生物医学工程
博士生导师科学学位专业名称生物医学工程
所在院系医学院
联系办法上海市四平路1239号，同济大学医学院702室。电话：021-65985003
研究方向/主要特长多能干细胞神经定向分化
主要任职
同济大学特聘教授，国家重大科学研究计划973项目首席科学家
科研业绩
1．WangZB,BoisvertE,ZhangX-Q,GuoM,FashoyinA,DuZW,ZhangSCandLiXJ.(2011)Fezf2regulatestelencephalicprecursordifferentiationfrommouseembryonicstemcells.CerebCortex.EpubAheadofPrint.2．ZhangX-Q,HuangTC,ChenJ,PankratzTM,XiJ-J,LiJ,YangY,LaVauteMT,LiX-J,AyalaM,BondarenkoIG,DuZ-W,JinY,GolosGTandZhangS-C.(2010)Pax6isahumanneuroectodermcellfatedeterminant.CellStemCell.7(1):90-100.3．HuB-Y,WeickJP,YuJ,MaL-X,ZhangX-Q,ThomsonJA,ZhangS-C.(2010)Neuraldifferentiationofhumaninducedpluripotentstemcellsfollowsdevelopmentalprinciplesbutwithvariablepotency.ProcNatlAcadSciUSA.107(9):4335-40.4．ZhangX-Q,ZhangS-C.(2010):Differentiationofneuralprecursorsanddopaminergicneuronsfromhumanembryonicstemcells.MethodsMolBiol.584:355-66.5．LiX-J,ZhangX-Q（共同第一）,JohnsonMA,WangZ-B,LavauteT,ZhangS-C.(2009)CoordinationofsonichedgehogandWntsignalingdeterminesventralanddorsaltelencephalicneurontypesfromhumanembryonicstemcells.Development.136(23):4055-63.6．ZhangX-Q,ZhangG,ZhangH,KarinM,BaiH,CaiD-S.(2008):HypothalamicIKKbeta/NF-kappaBandERstresslinkovernutritiontoenergyimbalanceandobesity.Cell.135(1):61-73.7．WangF-F,ChenX-Q,ZhangX-Q,MaL.(2008):Phosphorylationstateofmu-opioidreceptordeterminesthealternativerecyclingofreceptorviaRab4orRab11pathway.MolEndocrinol.22(8):1881-92.8．ZhangX-Q,WangF-F,ChenX-Q,ChenY-J,MaL.(2008):Post-endocyticfatesofdelta-opioidreceptorareregulatedbyGRK2-mediatedreceptorphosphorylationanddistinctbeta-arrestinisoforms.JNeurochem.106(2):781-92.9．ZhangX-Q,WangF-F,ChenX-Q,LiJ-L,XiangB,LiB-M,ZhangY-Q,MaL.(2005):Beta-arrestin1andbeta-arrestin2aredifferentiallyrequiredforphosphorylation-dependentandindependentinternalizationofdelta-opioidreceptors.JNeurochem.95(1):169-78.10．KangJ-H,ShiY-F,XiangB,QuB,SuW-J,ZhuM,ZhangM,BaoG-B,WangF-F,ZhangX-Q,YangR-X,FanF-G,GangP,MaL.(2005):Anuclearfunctionofbeta-arrestin1inGPCRsignaling:regulationofhistoneacetylationandgenetranscription.Cell.123(5):833-47.11．LiJ-L,XiangB,SuW-J,ZhangX-Q,MaL.(2003):Agonistinducedformationofopioidreceptor-GRK-GbetagammacomplexinmembraneisrequiredforGRK2functionsinvivo.JBiolChem.278(32),30219-26.12．FanX-L,ZhangJ-S,ZhangX-Q,YueW,MaL.(2003):Differentialregulationofbeta-arrestin1andbeta-arrestin2geneexpressioninratbrainbymorphine.Neuroscience.117(2):383-9.13．FanX-L,ZhangJ-S,ZhangX-Q,MaL.(2003):Chronicmorphinetreatmentandwithdrawalinduceup-regulationofc-JunN-terminalkinase3geneexpressioninratbrain.Neuroscience.122(4):997-1002.14．FanX-L,ZhangJ-S,ZhangX-Q,YueW,MaL.(2002):AcuteandchronicmorphinetreatmentsandmorphinewithdrawaldifferentiallyregulateGRK2andGRK5geneexpressioninratbrain.Neuropharmacology43(5):809-16.
