摘要/Abstract

摘要： 氟代脱氧葡萄糖正电子发射体摄影技术 -计算机体层摄影技术（ 18F-fluoro-deoxyglucose positron emission tomography-computed tomography， 18F-FDG PET/CT，简称 PET/CT）已成为淋巴瘤分期及预后评估的重要影像学方法。因淋巴瘤各亚型的生物学特性、治疗反应和预后差异较大，该文主要对 PET/CT在霍奇金淋巴瘤（Hodgkin lymphoma，HL）、弥漫大 B细胞淋巴瘤（diffused large B-cell lymphoma，DLBCL）中的预后评估进展进行综述，阐述了治疗中期 PET/CT在 HL预后评估中的积极意义，以及在 DLBCL预后评估作用中存在的争议，并论述了半定量法在未来应用的前景。
关键词: 氟代脱氧葡萄糖正电子发射体摄影技术 -计算机体层摄影技术, 淋巴瘤, 霍奇金淋巴瘤, 弥漫大 B细胞淋巴瘤, 预后评估, 半定量法
Abstract:
18F-fluoro-deoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) has been used as a crucial imaging modality for staging and prognosis evaluation in the patients with lymphoma. Since biological characteristics, treatment responses and prognosis vary in different subtypes of lymphoma, this review mainly focused on progress of 18F-FDG PET/CTevaluationin prognosis of Hodgkin lymphoma (HL)and diffused large B-cell lymphoma (DLBCL). The significance in prognostic evaluation of interim 18F-FDG PET/CT in HL is well-known, but it still remains controversy in DLBCL. Moreover, the semi-quantitative method of 18F-FDG PET/CT evaluation in lymphoma has bright future.
Key words: 18F-fluoro-deoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT), lymphoma, Hodgkin lymphoma (HL), diffusedlarge B-cell lymphoma (DLBCL), prognostic evaluation, semi-quantitative method


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