徐建雄
职称：教授
所属学科：动物营养与饲料科学
研究方向：
（1）分子营养
（2）氧化应激与动物健康
（3）生态养殖
电话：
E-mail：jxxu1962@sjtu.edu.cn
联系地址：上海交通大学农业与生物学院A楼3-307室

个人简介：
徐建雄，1962年生，中共党员，博士，教授，博士生导师。中国农业大学畜牧专业毕业获学士学位，中国农业科学院动物营养学硕士学位，南京农业大学博士学位；美国国立卫生研究院（NIH）细胞生物学实验室访问****。上海市曙光****，上海市技术预见专家，中国畜牧兽医学会动物营养学分会理事，国家科学技术奖、教育部科学技术奖和国家自然科学基金评审专家。主要从事肠道营养、氧化应激和健康、生态养殖研究以及新型饲料添加剂研发。先后完成国家自然科学基金、国家科技攻关项目、公益性行业（农业）科研专项、国家重点研发计划项目以及其他省部级科研项目30余项，在Am J Physiol Cell Physiol，Journal of Animal Science，Oxidative Med Cell Longev，Nutrition，Food andNutrition Research，动物营养学报，畜牧兽医学报等发表论文120多篇，获省部级科技进步奖二等奖3项和三等奖6项，上海市优秀发明一等奖1项，获国家发明专利12项。
主要成果：
近期代表性论文：
1. Zhen Luo, Xue Xu, Takami Sho, Jing Zhang, Weina Xu, Jianbo Yao, and Jianxiong Xu. ROS-induced autophagy regulates porcine trophectoderm cell apoptosis,proliferation, and differentiation. Am J Physiol Cell Physiol 2019 316:C198-C209
2. Zhen Luo, Xue Xu, Takami Sho, Wenli Luo, Jing Zhang, Weina Xu, Jianbo Yao, and Jianxiong Xu. Effects of n-acetyl-cysteine supplementation in late gestational diet on maternal-placental redox status, placental NLRP3 inflammasome, and fecal microbiota in sows. J.Anim.Sci.2019.97:1757–1771 doi:10.1093/jas/skz058
3. W. L. Luo , Z. Luo,X. Xu,S. Zhao,S. H. Li,T. Sho,J. Yao,J. Zhang,W. N. Xu,and J. X. Xu The Effect of Maternal Diet with Fish Oil on Oxidative Stress and Inflammatory Response in Sow and New-Born Piglets Oxidative Medicine and Cellular Longevity 2019, Article ID **, https://doi.org/10.1155/2019/**
4. Zhen Luo, Xue Xu, Sen Zhao, Takami Sho, Wenli Luo, Jing Zhang, Weina Xu, Kong Hon and Jianxiong Xu. Inclusion of microbe-derived antioxidant during pregnancy and lactation attenuates high-fat diet-induced hepatic oxidative stress, lipid disorders, and NLRP3 inflammasome in mother rats and offspring. Food & Nutrition Research 2019, 63: 3504 - http://dx.doi.org/10.29219/fnr.v63.3504
5. Z. Luo, S. Yu, Y. Zhu, J. Zhang, W. Xu & J. Xu.Effect of various levels of isoflavone aglycone-enriched fermented soybean meal on redox status, serum hormones and milk quality in ewes. S. Afr. J. Anim. Sci. 2018 48(4) 673-682
6. Q. Guo, Z.Luo, L. Zhu,X. Cai,C. Xu, J. Zhang, W. Xu & J.Xu. Weaning induced cell cycle arrest through up-regulation of p21 and p27 in the jejunum of piglets. S.Afr.J.Anim.Sci. 2018，48：1099-1100
7. Takami Sho JianXiong Xu. Role and mechanism of ROS scavengers in alleviating NLRP3‐mediated inflammation. Biotechnology and Applied Biochemistry.2018 66,(1):4–13
8. Zhen Luo, Wenli Luo, Shaohua Li, Sen Zhao, Takami Sho, Xue Xu, Jing Zhang, Weina Xu,Jianxiong Xu. Reactive oxygen species mediated placental oxidative stress, mitochondrial content, and cell cycle progression through mitogen-activated protein kinases in intrauterine growth restricted pigs Reproductive Biology 18 (2018) 422–431
9. Xuan Cai, Lihui Zhu, Xiaolian Chen,Yongshuai Sheng, Qi Guo, Jian Bao &Jianxiong Xu X. XO or H2O2 induced IPEC-J2 cell as a new in vitro model for studying apoptosis in post-weaning piglets. Cytotechnology .2016. 68:713–724
10. Zhen Luo, Wei Zhu, Qi Guo,Wenli Luo, Jing Zhang, Weina Xu, and Jianxiong Xu. Weaning Induced Hepatic Oxidative Stress, Apoptosis, and Aminotransferases through MAPK Signaling Pathways in Piglets. Oxidative Med Cell Longev, 2016, Article ID **, 10 pages
11. Qi Guo, Xuan Cai, Congcong Xu, Zhen Luo, Yongshuai Sheng, Jian Bao,Xiaolian Chen & Jianxiong Xu. Effects of dietary supplementation with Nacetyl cysteine on antioxidant capacities and the expression of inflammatory cytokines in weaned Piglets. Italian Journal of Animal Science, 2016 .15(4): 634–641
12. Jianxiong Xu , Congcong, Xiaolian Chen, Xuan Cai,Shoufeng Yang, Yongshuai Sheng, Tian Wang. Regulation of an antioxidant blend on intestinal redox status and major microbiota in early weaned piglets. Nutrition. 2014.30:584–589
13. C. C. Xu, S. F. Yang, L. H. Zhu, X. Cai, Y. S. Sheng, S. W. Zhu and J. X. Xu. Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets. J. Anim. Sci. 2014.92:1504-1511
14. L. H. Zhu, J. X. Xu, S. W. Zhu, X. Cai, S. F. Yang, X. L. Chen and Q. Guo. Gene expression profiling analysis reveals weaning-induced cell cycle arrest and apoptosis in the small intestine of pigs. J. Anim. Sci. 2014.92 :996-1006
15. Xuan Cai, Xiaolian Chen,Xiaochun Wang,Congcong Xu,Qi Guo ,Lihui Zhu,Shuwen Zhu, Jianxiong Xu. Pre-protective effect of lipoic acid on injury induced by H2O2 in IPEC-J2 cells. Molecular and Cellular Biochemistry. 2013 378:73-81
16. Lihui Zhu, Xuan Cai1, Qi Guo, Xiaolian Chen, Suwen Zhu and Jianxiong Xu. Effectof N-acetylcysteine on enterocyte apoptosis and intracellular signalling pathways response to oxidative stress in weaned piglet. British Journal of Nutrition, 2013.110, 1938–1947
17. L. H. Zhu, K. L. Zhao, X. L. Chen and J. X. Xu. Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs. J. Anim. Sci.2012.90:2581–2589
18. X. L. Chen, L. Z. Gong and J. X. Xu Preventive effect of probiotics on sperm damage induced by diet Oxidative stress in rats. Animal, 2012.1 of 6
代表性授权发明专利：
1. 徐建雄猪用营养性抗应激生物修复组合物及其制备方法 ZL.5
2. 徐建雄陈小连提高雄性动物精液品质的复合抗氧化剂ZL 8.3
3. 徐建雄 抗氧化保健鸡蛋的生产方法及其使用的复合抗氧化剂ZL 2.2
4. 徐建雄李龙复合益生菌发酵饲料的制备方法ZL 8.5
5. 徐建雄 猪双低菜籽粕复合饲料添加剂ZL1.2
6. 徐芳张闻中徐建雄 王举德纳米沸石组装体固载植酸酶复合饲料添加剂的制备方法 ZL 9.4
7. 徐建雄刘永德 叶陈梁抗仔猪细菌性疫病复合卵黄抗体制剂的制备方法ZL9.3
8. 刘永德;徐建雄;叶陈梁;汪 毅卵黄抗体饲料添加剂的制备方法ZL 2.3