导师姓名： 周滟 专业代码： 100207
性别： 女 专业名称： 影像医学与核医学
培养单位： 附属仁济医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市浦建路160号仁济医院放射科
邮编： 200127 邮箱地址： clare1475@hotmail.com

研究方向 (点击浏览详细信息)
脑肿瘤及精神疾病等的脑功能成像

社会任职
上海市医学会放射科专科分会委员会委员
上海医学会放射科专科分会神经组 副组长
上海市图形图像学学会 理事
中国神经科学学会会员
中国医师协会中国放射医师分会神经专委会委员
北美放射学会会员，欧洲放射学会会员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
U** 多元医学影像数据智能分析交换技术与系统应用 国家自然科学基金联合基金项目 重点支持项目 2020-01~2023-12 250万元 课题参与人
PYIV-17-003 基于MR机器学习探索SVCI风险预测的前瞻性临床研究 上海交通大学医学院附属仁济医院临床科研创新培育基金计划 2018-01~2020-12 15万元 课题负责人
** 前瞻性探索SVCI的评价新指标—NAWM的显微病变 上海交通大学高峰高原“双百人”计划 2017-07~2020-06 100万元 课题负责人
** 探索血管性认知功能障碍病情和预后的新指标-正常表观白质的微改变 上海市科委西医引导项目 2017-06~2020-06 20万元 课题负责人
** 青少年网络游戏成瘾认知行为治疗的调节机制探索 国家自然基金 2016-01~2019-12 67.4万元 课题负责人
** 脑小血管病认知障碍的多模式磁共振研究 上海市科委西医引导项目 2014-01~2016-06 10万元 课题参与人
** 创伤后应激障碍“闪回”症状的脑功能网络纵向研究 国家自然科学基金 2014-01~2017-12 60万元 课题参与人
13QA** 创伤性应激障碍脑网络基础前瞻性研究 上海市科委“启明星”计划 2013-07~2015-06 20万元 课题参与人
** 融合多模态神经影像信息的青少年网络游戏成瘾特定结构和功能网络研究 国家自然基金 2012-01~2015-12 58万元 课题负责人
114119a0900 青少年网络成瘾奖赏系统融合多模态神经影像信息的脑功能研究 上海市科委医学引导项目 2011-01~2013-06 10万元 课题负责人
** 青少年首发抑郁执行功能、DTI、FMRI变化及其病理机制研究 国家自然基金 2010-01~2012-12 30万元 课题参与人
06ZR14122 缺血性脑白质病变与血管性痴呆的关系-功能磁共振研究 上海市科委,自然基金 2006-09~2008-08 8万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Lin F, Han X, Wang Y, Ding W, Sun Y, Zhou Y, Lei H. （通讯作者） Sex-specific effects of cigarette smoking on caudate and amygdala volume and resting-state functional connectivity. Brain Imaging and Behavior 2020 Jan 2. doi: 10.1007/s11682-019-00227-z.
Yao Wang, Danyang Tu, Jing Du, Xu Han, Yawen Sun, Qun Xu, Guangtao Zhai, Yan Zhou. （通讯作者） A Deep Learning-Based Model for Classification of Different Cognitive Performances in Subcortical Ischemic Vascular Disease with MRI Data. Frontiers in Neuroscience 2019 19;13:627.
Sun Yawen,Wang Yao,Han Xu,Jiang Wenqing,Ding Weina,Cao Mengqiu,Du Yasong Lin Fuchun,Xu Jianrong,Zhou Yan Zhou Yan Sex differences in resting-state cerebral activity alterations in Internet gaming disorder. Brain Imaging and Behavior 2019 13(5):1406-1417.
Xiaowei Wu, Xin Ge, Jing Du, Yao Wang, Yawen Sun, Xu Ha, Weina Ding, Mengqiu Cao, Qun Xu, Yan Zhou. （通讯作者） Characterizing the penumbras of white matter hyperintensities and their associations with cognitive function in patients with subcortical vascular mild cognitive impairment. Frontiers on neurology. 2019 12;10:348.
Du J, Wang Y, Zhi N, Geng J, Cao W, Yu L, Mi J, Zhou Y （通讯作者）, Xu Q, Wen W, Sachdev P. Structural brain network measures are superior to vascular burden scores in predicting early cognitive impairment in post stroke patients with small vessel disease. NeuroImage: Clinical 2019 22.102712
Cao M, Ding W, Han X, Suo S, Sun Y, Wang Y, Qu J, Zhang X, Zhou Y. （通讯作者） Brain T1p mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study. J Neurooncol. 2019 141(1):245-252
Xu Han,Yao Wang,Wenqing Jiang,Xiaochen Bao,Yawen Sun, Weina Ding,Mengqiu Cao,Xiaowei Wu,Yasong Du,Yan Zhou （通讯作者） Resting-State Activity of Prefrontal-Striatal Circuits in Internet Gaming Disorder: Changes With Cognitive Behavior Therapy andPredictors of Treatment Response Front Psychiatry. 2018 2018, 3;9:341.
Hao Hu, Yawen Sun, Shanshan Su, Yao Wang, Yongming Qiu, Xi Yang, Yan Zhou （通讯作者）, Zeping Xiao, Zhen Wang. Cortical surface area reduction in identification of subjects at high risk for post-traumatic stress disorder: A pilot study. Aust N Z J Psychiatry. 2018 1:57.
Xu Han , Xiaowei Wu , Yao Wang, Yawen Sun, Weina Ding , Mengqiu Cao , Yasong Du, Fuchun Lin, Yan Zhou. （通讯作者） Alterations of resting-state static and dynamic functional connectivity of the dorsolateral prefrontal cortex in subjects with internet gaming disorder. Front Hum Neurosci. 2018 6;12:41.
Mengqiu Cao, Shiteng Suo, Xu Han, Ke Jin, Yawen Sun, Yao Wang, Jianxun Qu, Xiaohua Zhang, Yan Zhou （通讯作者） Application of a Simplified Method for Estimating Perfusion Derived from Diffusion-Weighted MR Imaging in Glioma Grading. Front Aging Neurosci. 2018 8;9:432.
Yao Wang,Wenwei Cao, Yawen Sun, Xue Chen, Weina Ding, Yan Zhou* （通讯作者）, Qun Xu, Jianrong Xu, Shiteng Suo. White Matter Integrity in Subcortical Vascular Cognitive Impairment: A Multimodal Structural MRI Study Current Alzheimer Research 2017 14, 1-9
Xu Han, Shiteng Suo, Yawen Sun, Jinyan Zu, Yan Zhou* （通讯作者）, Zengai Chen,Jianrong Xu. Apparent Diffusion Coefficient (ADC) Measurement in Glioma: Influence of Region-of-Interest Determination Methods on ADC Values, Interobserver Variability, Time Efficiency and Diagnostic Ability. Magnetic Resonance Imaging 2017 45(3):722-730.
Mengqiu Cao, Lijun Qian, Xuebin Zhang, Xinjun Suo, Qing Lu, Huilin Zhao, Jialin Liu, Jianxun Qu, Yan Zhou （通讯作者）, Jianrong Xu, Shiteng Suo Monitoring Leiomyoma Response to Uterine Artery Embolization Using Diffusion and Perfusion Indices from Diffusion-Weighted Imaging. BioMed Research International 2017 2017:**
Yawen Sun, Xin Ge, Xu Han, Wenwei Cao, Yao Wang, Weina Ding, Mengqiu Cao, Yong Zhang, Qun Xu, Yan Zhou* （通讯作者）, Jianrong Xu. Characterizing brain iron deposition in patients with subcortical vascular mild cognitive impairment using quantitative susceptibility mapping: A potential biomarker. Frontiers in Aging Neuroscience 2017 30;9:81.
Wen-wei Cao, Yao Wang, Quan Dong, Xue Chen, Yan-sheng Li,Yan Zhou （通讯作者）, Gao, Ye Deng, Qun Xu Deep microbleeds and periventricular white matter disintegrity are independent predictors of attention/executive dysfunction in non-dementia patients with small vessel disease. International Psychogeriatric Association 2017 29(5):793-803
Yawen Sun,Wenwei Cao,Weina Ding,Yao Wang,Xu Han,Yan Zhou* （通讯作者）,Qun Xu,Yong Zhang,Jianrong Xu. Cerebral blood flow alterations as assessed by 3D ASL in cognitive impairment in patients with subcortical vascular cognitive impairment: A marker for disease severity. Frontiers in Aging Neuroscience 2016 31;8:211
Hu H, Zhou Y （共同第一作者）, Wang Q, Su S ,Qiu Y, Ge J, Wang Z, Xiao Z。 Association of abnormal white matter integrity in the acute phase of motor vehicle accidents with post-traumatic stress disorder. J Affect Disord 2016 15;190:714-22
汪耀,孙雅文,徐群,陈雪,丁伟娜,周滟 （通讯作者）,唐辉,董荃,许建荣 皮质下血管性认知障碍的脑功能网络研究 中华行为医学与脑科学杂志 2015 24(8):698-70
Wei H, Dibb R, Zhou Y, Sun Y, Xu J, Wang N, Liu C. Streaking Artifact Reduction for Quantitative Susceptibility Mapping of Sources with Large Dynamic Range. NMR in Biomedicine 2015 DOI: 10.1002/nbm.3383
Ruoyang Shi, Qiuying Yao, Lianming Wu, Qinyi Zhou, Qing Lu, Runlin Gao, Jiani Hu, Leslie Kao, Ashika Bains, Yan Zhou （通讯作者）, Jianrong Xu T2* mapping at 3.0 tesla MRI for the differentiation of papillary thyroid carcinoma from benign thyroid nodules. Journal of Magnetic Resonance Imaging 2015 2015 Sep 21. doi: 10.1002/jmri.25041
李磊,陈雪,孙锦华,孙雅文,庄治国,丁伟娜,周滟 （通讯作者）,许建荣,杜亚松 青少年网络游戏成瘾脑灌注的改变 中国医学计算机成像杂志 2015 21（1）：11-16
Wang Y, Yin Y, Sun YW, Zhou Y （通讯作者）, Chen X, Ding WN, Wang W, Li W, Xu JR, Du YS. Decreased prefrontal lobe interhemispheric functional connectivity in adolescence with Internet gaming disorder: A primary study using resting-state fMRI. PLoS One. 2015 4;10(3):e**. doi: 10.1371/journal.pone.**.
Ding W, Cao W, Wang Y, Sun Y, Chen X, Zhou Y （通讯作者）, Xu Q ,Xu J. Altered functional connectivity in patients with subcortical vascular cognitive impairment—a resting-state functional magnetic resonance imaging study. Plos One 2015 16;10(9):e**. doi: 10.1371/journal.pone.**
Sun YW, Hu H, Wang Y, Ding WN, Chen X, Wan JQ, Zhou Y （通讯作者）, Wang Z*, Xu JR. Inter-hemispheric functional and anatomical connectivity abnormalities in traffic accident-induced PTSD: a study combining fMRI and DTI. J Affect Disord. 2015 188:80-8.
Ding W, Cao W, Wang Y, Sun Y, Chen X, Zhou Y* （通讯作者）, Xu Q ,Xu J Altered functional connectivity in patients with subcortical vascular cognitive impairment—a resting-state functional magnetic resonance imaging study. Plos One 2015 16;10(9):e**.
陈雪,丁伟娜,孙雅文,周滟 （通讯作者）,庄治国,徐群,唐辉,许建荣 血管性认知功能障碍分数低频振幅的fMRI研究 实用放射学杂志 2015 31(2):177-181
Ding WN, Sun JH, Sun YW, Chen X, Zhou Y （通讯作者）, Zhuang ZG, Li L, Zhang Y, Xu JR, DuYS. Trait impulsivity and impaired prefrontal impulse inhibition function in adolescents with internet gaming addiction revealed by a Go/No-Go fMRI study. Behav Brain Funct. 2014 30;10(1):20. doi: 10.1186/1744-9081-10-2
Sun Y, Sun J, Zhou Y （通讯作者）, Ding W, Chen X, Zhuang Z, Xu J, Du Y. Assessment of in vivo microstructure alterations in gray matter using DKI in internet gaming addiction. Behav Brain Funct. 2014 2014 24;10(1):37. DOI:10/1186/ 1744- 9081- 10-37
Xue Chen, Yao Wang, Yan Zhou （通讯作者）, Yawen Sun, Weina Ding, Zhiguo Zhuang, Jianrong Xu, Yasong Du. Different resting-state functional connectivity alterations in smokers and non-smokers with Internet gaming addiction. BioMed Research International 2014 Volume2014,Article ID 825787,9 pages http://dx.doi.org/10.1155/ 2014/ 825787
Wee CY, Zhao Z, Yap PT, Wu G, Shi F, Price T, Du Y, Xu J, Zhou Y, Shen D Wee CY, Zhao Z, Yap PT, Wu G, Shi F, Price T, Du Y, Xu J, Zhou Y, Shen D. Disrupted brain functional network in internet addiction disorder:a resting-state functional magnetic resonanceimaging study. PLoS One. 2014 Sep 16;9(9):e107306. doi: PLoS One. 2014 16;9(9):e107306.
Qi Feng, Xue Chen, Jinhua Sun, Yan Zhou* （通讯作者）, Yawen Sun, Weina Ding, Yong Zhang, Zhiguo Zhuang, Jianrong Xu ,Yasong Du. Voxel-level comparison of arterial spin-labeled perfusion magnetic resonance imaging in adolescents with internet gaming addiction Behav Brain Funct. 2013 12;9(1):33.. doi: 10.1186/1744-9081-9-33
丁伟娜,孙锦华,孙雅文,李磊,周滟 （通讯作者）,杜亚松,许建荣. 青少年网络游戏成瘾奖赏系统的fMRI研究. 临床放射学杂志, 2013 .9:1226-1229
Yawen Sun, Zhen Wang, Weina Ding, Jieqing Wan, Zhiguo Zhuang, Yong Zhang, Yijun Liu ,Yan Zhou* （通讯作者）, Jianrong Xu. Alterations in white matter microstructure as vulnerability factors and acquired signs of traffic accident-induced PTSD. PLoS ONE 2013 8(12):e83473. doi: 10.1371/journal.pone.
Ding WN, Sun JH, Sun YW, Zhou Y* （通讯作者）, Li L, Xu JR, Du YS Altered Default Network Resting-State Functional Connectivity in Adolescents with Internet Gaming Addiction. PLoS ONE 2013 2013,8(3):e59902. doi:10.1371/journal.po
李磊,孙雅文,王振,秦玲娣,苏珊珊,万杰清,周滟 （通讯作者）,许建荣. 创伤后应激障碍患者创伤暴露后不同时期静息脑功能初探. 放射学实践 2013 3:256-259
孙雅文,王振,秦玲娣,苏珊珊,路青,周滟* （通讯作者）,许建荣. 运用VBM方法检测创伤后应激障碍患者发病前脑灰质容积的改变. 临床放射学杂志 2012 30(1):764-768
Yan Zhou, Zhen Wang, Ling-di Qin , Jie-qing Wan, Ya-wen Sun, Shan-shan Su , Wei-na Ding , Jian-rong Xu. Early altered resting-state functional connectivity predicts the severity of post-traumatic stress disorder symptoms in acutely traumatized subjects. PLOS ONE 2012 7(10):e46833. doi:10.1371/jo urnal.pone.
Fuchun Lin, Yan Zhou （共同第一作者）, Yasong Du, Lindi Qin2, Zhimin Zhao, Jianrong Xu, Hao Lei Abnormal White Matter Integrity in Adolescents with Internet Addiction Disorder: A Tract-Based Spatial Statistics Study. PLoS ONE 2012 7(1):30253-30253
Ling-di Qin, Zhen Wang, Ya-wen Sun, Jie-qing Wan, Shan-shan Su , Yan Zhou* （通讯作者）, Jian-rong Xu. A preliminary study of alterations in default network connectivity in posttraumatic stress disorder patients following recent trauma. Brain Research 2012 1484(12):50-56.
Zhou Y, Qin LD, Chen J, Qian LJ, Tao J, Fang YR, Xu JR. Brain microstructural abnormalities revealed by diffusion tensor images in patients with treatment-resistant depression compared with major depressive disorder before treatment. Eur J Radiol 2011 80(2):450-454
秦玲娣,周滟* （通讯作者）,赵志民,路青,戈欣,李磊,杜亚松,许建荣. 静息态脑功能成像在青少年网络成瘾中的初步研究. 临床放射学杂志 2011 30(1):7-10
Sun YW, Qin LD, Zhou Y* （通讯作者）, Xu Q, Qian LJ, Tao J, Xu JR. Abnormal Functional Connectivity in Patients with Vascular Cognitive Impairment, No Dementia: A Resting-State Functional Magnetic Resonance Imaging Study. Behaviour brain research 2011 223(2):388-394
Zhou Y, Xu Q, Qin LD, Qian LJ, Cao WW, Xu JR. A primary study of diffusion tensor imaging-based histogram analysis in vascular cognitive impairment with no dementia. Journal of Clin Neurol Neurosurg 2011 113(2):92-97
Xu Q*, Zhou Y* （共同第一作者）, Li YS, Cao WW, Lin Y, Pan YM, Chen SD Diffusion Tensor Imaging Changes Correlate with Cognition Better than Conventional MRI Findings in Patients with Subcortical Ischemic Vascular Disease. Dement Geriatr Cogn Disord. 2010 30(4):317-326
Zhou Y, Lin FC, Du YS, Qin LD, Zhao ZM, Xu JR, Lei H. Gray matter abnormalities in Internet addiction: A voxel-based morphometry study. Eur J Radiol 2009 doi:10.1016/ j.ejrad. 2009.10.025
周滟,秦玲娣,徐群,曹玮文,路青,李磊,戈欣,柴伟明,许建荣. 运用DTI直方图分析血管性认知功能障碍患者正常表现白质损害与认知功能的关系 临床放射学杂志 2009 28(8):1060-1064.
秦玲娣,周滟 （通讯作者）,陈俊,朱炯,陶静,钱黎俊,许建荣. 难治性抑郁症患者静息状态默认网络改变的初步研究. 中国医学影像技术 2009 25(12):2182-2185
Zhou Y, Lin FC, Zhu J, Zhuang ZG, Li YS, Tao J, Qian LJ, Xu JR, Lei H Whole brain diffusion tensor imaging histogram analysis in vascular cognitive impairment. ournal of the Neurological Sciences 2008 268（1-2）:60-64
周滟 （共同第一作者）,林富春,朱炯,李焰生,钱黎俊,陶静, 许建荣. 运用MRI及DTI直方图分析评价皮质下白质病变与血管性认知功能障碍的关系 医学影像学杂志， 2008 18(6):557-581
周滟,陶静,林富春,朱炯,钱黎俊,路青,李磊,戈欣,许建荣,雷皓. 无痴呆的血管性认知功能损害全脑DTI直方图分析 放射学实践 2008 23(3):254-257
周滟,林富春,朱炯,陶静,李磊,路青,戈欣,许建荣,雷皓 血管性认知功能损害的全脑DTI直方图分析。 实用放射学杂志 2007 23(10):971-974
周滟,林富春,朱炯,陶静,李磊,路青,戈欣,范瑜,许建荣,雷皓. 皮质下血管性痴呆的全脑DTI直方图分析_初步探索 中国医学影像技术 2007 23(4):479-481